WSP/ICP – serie

Linus Pauling called haemoglobin the most interesting and important of molecules. This important volume shows how X-ray crystallography was used to determine its bewilderingly complex atomic structure and to unravel the stereochemical mechanisms of its respiratory functions. It introduces isomorphous replacement with heavy atoms which led to the first protein structures, haemoglobin and its simpler relative myoglobin. Later papers deal with the stereochemistry of the cooperative effects of haemoglobin, with the relationships between the structures and impaired functions of abnormal haemoglobin, with species adaptation of haemoglobin, and with its action as a drug receptor and as an oxygen sensor. The final papers deal with amino acid repeats which act as polar zippers and their role in certain inherited neurodegenerative diseases.

Linus Pauling called haemoglobin the most interesting and important of molecules. This important volume shows how X-ray crystallography was used to determine its bewilderingly complex atomic structure and to unravel the stereochemical mechanisms of its respiratory functions. It introduces isomorphous replacement with heavy atoms which led to the first protein structures, haemoglobin and its simpler relative myoglobin. Later papers deal with the stereochemistry of the cooperative effects of haemoglobin, with the relationships between the structures and impaired functions of abnormal haemoglobin, with species adaptation of haemoglobin, and with its action as a drug receptor and as an oxygen sensor. The final papers deal with amino acid repeats which act as polar zippers and their role in certain inherited neurodegenerative diseases.

This book is a revised and updated version of the most comprehensive text on nuclear and subnuclear physics, first published in 1995. It maintains the original goal of providing a clear, logical, in-depth, and unifying treatment of modern nuclear theory, ranging from the nonrelativistic many-body problem to the standard model of the strong, electromagnetic, and weak interactions. In addition, new chapters on the theoretical and experimental advances made in nuclear and subnuclear physics in the past decade have been incorporated.Four key topics are emphasized: basic nuclear structure, the relativistic nuclear many-body problem, strong-coupling QCD, and electroweak interactions with nuclei. New chapters have been added on the many-particle shell model, effective field theory, density functional theory, heavy-ion reactions and quark-gluon plasma, neutrinos, and electron scattering.This book is designed to provide graduate students with a basic understanding of modern nuclear and hadronic physics needed to explore the frontiers of the field. Researchers will benefit from the updates on developments and the bibliography.

Our Place in the Universe tells the story of our world, formation of the first galaxies and stars formed from great clouds containing the primordial elements made in the first few minutes; birth of stars, their lives and deaths in fiery supernova explosions; formation of the solar system, its planets and many moons; life on Earth, its needs and vicissitudes on land and in the seas; finally exoplanets, planets that surround distant stars. Interspersed in the text are short pieces on some of those who revealed these wonders to us.It is written in a very authoritative and readable form and contains more than 100 color prints of the marvelous galaxies, and nebula that have been taken from space-based and land-based telescopes carried by NASA missions, the European Space Agency, the European Southern Laboratory in Chile and many other sources.

Our Place in the Universe tells the story of our world, formation of the first galaxies and stars formed from great clouds containing the primordial elements made in the first few minutes; birth of stars, their lives and deaths in fiery supernova explosions; formation of the solar system, its planets and many moons; life on Earth, its needs and vicissitudes on land and in the seas; finally exoplanets, planets that surround distant stars. Interspersed in the text are short pieces on some of those who revealed these wonders to us.It is written in a very authoritative and readable form and contains more than 100 color prints of the marvelous galaxies, and nebula that have been taken from space-based and land-based telescopes carried by NASA missions, the European Space Agency, the European Southern Laboratory in Chile and many other sources.

The Nobel Prize, as founded in Alfred Nobel's will, was the first truly international prize. There is no other award with the same global scope and mission. The Nobel Prizes in Physics, Chemistry, Physiology or Medicine, Literature, Peace, and the Bank of Sweden Prize in Economic Sciences (from 1969) have not only captured the most significant contributions to the progress of mankind, they also constitute distinct markers of the major trends in their respective areas. The main reason for the prestige of the Prize today is, however, the lasting importance of the names on the list of Laureates and their contributions to human development.In celebration of the centennial of the Nobel Prize in 2001, this book offers a clear perspective on the development of human civilization over the past hundred years. The book serves to present the major trends and developments and also provide information about the life and philosophy of Alfred Nobel, the history of the Nobel Foundation, and the procedure for nominating and selecting Nobel Laureates.