Alan Yeung is the Co-Founder, President, and CEO of Where2Net, a provider of multi-channel software development tools and web applications. Dr. Yeung regularly speaks about wireless technologies and innovations at conference and seminars and is a guest lecturer at San Jose State University, where he teaches courses on Wireless Computing. Dr. Yeung received his MBA from University of California at Berkeley, his Ph.D. and MSChE from Stanford University, and a BSChE degree from University of Wisconsin. Spencer B. King, III, MD Director, Interventional Cardiology Emory University School of Medicine Atlanta, GA

• Part 1. Knowledge Foundation Section 1. Anatomy for Interventional Cardiology 1. Coronary Artery Anatomy for the Interventionalist, add some bypass anatomy? 2. Cardiac Chamber Anatomy (emphasize atrial septum and appendage)2’. Valve Anatomy (emphasize aortic and mitral)3. Peripheral Anatomy for the Interventionalist add radial (upper arm) anatomy Should we add carotid?Section 2. Physiology 4. The Coronary Circulation, emphasize FFR based concept 5. Physiological Evaluation of Renal Artery Stenosis: A Hemodynamic Approach5’. Sympathetic nervous system physiology (enphasize renal)Section 3. Pathophysiology 6. Valvular Pathophysiology 7. Arterial Disease Separate Coronary atherosclerosis from Arterial Disease8. Ventricular Pathophysiology Part 2. Equipment: Construction and Performance 9. Equipment for Percutaneous Coronary Intervention 10. Design and Construction of Stents 11. Adjunctive Devices: Atherectomy, Thrombectomy, Embolic Protections, IUVS, Doppler, and Pressure Wires11”. Aortic valvuloplasty equipment11’’: TAVR Equipment11’’’: ?Renal Dernervation equipment11’’’’ Closure devices11’’’’’Equiptment for structural heart disease interventions (ASD PFO etc) --This may precede TAVI, renal etcPart 3. Principles and Catheter Laboratory Equipment 12. X-Ray Cinefluorographic Systems 13. Operational Radiation Management for Patients and Staff 14. 15. X-Ray Computed Tomography and Magnetic Resonance Imaging of the Coronary Arteries 16. Intracardiac Echocardiography, OTC and FFR in the Catheterization Laboratory 17. Cardiac Catheterization Laboratory Physiologic Recorders 18. Digital Image Formats and Archiving Practices Part 4. Pharmacology Major update in content 19. Antithrombin Therapies 20. Antiplatelet Therapies in Contemporary Percutaneous Coronary Intervention 21. Thrombolytic Therapy 22. Radiographic Contrast Media 23. Renal Complications of Contrast Media 24. Patient Sedation in the Cardiovascular Catheterization Laboratory Part 5. Procedures 25. Diagnostic Procedures: Special Considerations25’ Radial Approach 26. Diagnostic Procedures: Peripheral Angiography 27. Adjunctive Diagnostic Techniques 28. Coronary Guidewire Manipulation 29. Coronary Balloon Angioplasty 30. Coronary Stenting, Bare Metal Stents, and Drug-Eluting Stents plus Bioabsorbable stents30’: Drug eluting balloon31. Rotational Atherectomy: Concepts and Practice 32” Instent restenosis 33. Basic Wire-Handling Strategies for Chronic Total Occlusion 34. Percutaneous Intervention in Chronic Total Coronary Occlusions 36. Distal Embolic Protection Devices 37. Intervention in Venous and Arterial Grafts 38. Special Considerations: Acute Myocardial Infarction 39. Complex Lesion Intervention: Bifurcation, Left Main Coronary Artery, and Ostial Lesions 40. Special Considerations: Small Vessel and Diffuse Disease 41. Special Patient Subsets: Diabetic and Elderly 42. Inoue-Balloon Mitral Valvuloplasty 43. Aortic Valvuloplasty and Future Solutions to Aortic Valve Disease44. Two TAVR techniques44. Balloon Pulmonary Valvuloplasty 44’Mitral clip44’’Atrial appendage closure45. Percutaneous Closure of Atrial Septal Defect and Patent Foramen Ovale 46. Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy 47. Coronary Vein Device Insertion 48. Device Retrieval Systems 49. Percutaneous Treatment of Coronary Artery Fistulas 50. Renal Artery Angioplasty and Stenting 50’: Renal denervation51. Iliac Angioplasty and Stenting 52. Endovascular Abdominal Aortic Aneurysm Repair 53. Carotid and Vertebral Artery Intervention Part 6. Complications and Management More case based54. Risk Stratification in Interventional Cardiology 55. Acute Threatened Coronary Closure 56. Subacute Closure 57. Coronary Artery Perforation 58. Embolization and No-Reflow During Percutaneous Coronary Intervention 59. Emergency Surgery 60. Complications of Peripheral Procedures 60’ Emergency resuscitation measuresPart 7. Medical Management of Risk Factors 61. Lipid-Lowering Therapy and the Interventional Cardiologist 62. Hypertension 63. Diabetes and Cardiovascular Disease 64. Nontraditional Risk Factors for AtherosclerosisPart 7’ Procedure selection (AUC and the “Heart Team”)64’ Appropriateness criteria for coronary revascularization 64’’ Appropriateness criteria for other procedures if there are anyPart 8. Preclinical and Clinical Trials 65. Preclinical Laboratory Functions 66. The Core Laboratory: Quantitative Coronary Angiography and Intravascular Ultrasound 67. How to Read Clinical Trials Part 9. Reimbursement and Hospital Finance 68. Cost-Effectiveness 69. Quality Assurance and Quality Improvement in Interventional Cardiology69’ ACO Part 10. Principles of Innovation 70. Innovation and Interventional Cardiology: Looking Back, Thinking Ahead 71. Principles of Innovation: Transforming Clinical Needs into Viable Inventions 71’’’ Regulatory considerations71’. Web based learning71’’. Web based clinical careIndex

Alan Yeung is the Co-Founder, President, and CEO of Where2Net, a provider of multi-channel software development tools and web applications. Dr. Yeung regularly speaks about wireless technologies and innovations at conference and seminars and is a guest lecturer at San Jose State University, where he teaches courses on Wireless Computing. Dr. Yeung received his MBA from University of California at Berkeley, his Ph.D. and MSChE from Stanford University, and a BSChE degree from University of Wisconsin. Spencer B. King, III, MD Director, Interventional Cardiology Emory University School of Medicine Atlanta, GA

• Part 1. Knowledge Foundation Section 1. Anatomy for Interventional Cardiology 1. Coronary Artery Anatomy for the Interventionalist, add some bypass anatomy? 2. Cardiac Chamber Anatomy (emphasize atrial septum and appendage)2’. Valve Anatomy (emphasize aortic and mitral)3. Peripheral Anatomy for the Interventionalist add radial (upper arm) anatomy Should we add carotid?Section 2. Physiology 4. The Coronary Circulation, emphasize FFR based concept 5. Physiological Evaluation of Renal Artery Stenosis: A Hemodynamic Approach5’. Sympathetic nervous system physiology (enphasize renal)Section 3. Pathophysiology 6. Valvular Pathophysiology 7. Arterial Disease Separate Coronary atherosclerosis from Arterial Disease8. Ventricular Pathophysiology Part 2. Equipment: Construction and Performance 9. Equipment for Percutaneous Coronary Intervention 10. Design and Construction of Stents 11. Adjunctive Devices: Atherectomy, Thrombectomy, Embolic Protections, IUVS, Doppler, and Pressure Wires11”. Aortic valvuloplasty equipment11’’: TAVR Equipment11’’’: ?Renal Dernervation equipment11’’’’ Closure devices11’’’’’Equiptment for structural heart disease interventions (ASD PFO etc) --This may precede TAVI, renal etcPart 3. Principles and Catheter Laboratory Equipment 12. X-Ray Cinefluorographic Systems 13. Operational Radiation Management for Patients and Staff 14. 15. X-Ray Computed Tomography and Magnetic Resonance Imaging of the Coronary Arteries 16. Intracardiac Echocardiography, OTC and FFR in the Catheterization Laboratory 17. Cardiac Catheterization Laboratory Physiologic Recorders 18. Digital Image Formats and Archiving Practices Part 4. Pharmacology Major update in content 19. Antithrombin Therapies 20. Antiplatelet Therapies in Contemporary Percutaneous Coronary Intervention 21. Thrombolytic Therapy 22. Radiographic Contrast Media 23. Renal Complications of Contrast Media 24. Patient Sedation in the Cardiovascular Catheterization Laboratory Part 5. Procedures 25. Diagnostic Procedures: Special Considerations25’ Radial Approach 26. Diagnostic Procedures: Peripheral Angiography 27. Adjunctive Diagnostic Techniques 28. Coronary Guidewire Manipulation 29. Coronary Balloon Angioplasty 30. Coronary Stenting, Bare Metal Stents, and Drug-Eluting Stents plus Bioabsorbable stents30’: Drug eluting balloon31. Rotational Atherectomy: Concepts and Practice 32” Instent restenosis 33. Basic Wire-Handling Strategies for Chronic Total Occlusion 34. Percutaneous Intervention in Chronic Total Coronary Occlusions 36. Distal Embolic Protection Devices 37. Intervention in Venous and Arterial Grafts 38. Special Considerations: Acute Myocardial Infarction 39. Complex Lesion Intervention: Bifurcation, Left Main Coronary Artery, and Ostial Lesions 40. Special Considerations: Small Vessel and Diffuse Disease 41. Special Patient Subsets: Diabetic and Elderly 42. Inoue-Balloon Mitral Valvuloplasty 43. Aortic Valvuloplasty and Future Solutions to Aortic Valve Disease44. Two TAVR techniques44. Balloon Pulmonary Valvuloplasty 44’Mitral clip44’’Atrial appendage closure45. Percutaneous Closure of Atrial Septal Defect and Patent Foramen Ovale 46. Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy 47. Coronary Vein Device Insertion 48. Device Retrieval Systems 49. Percutaneous Treatment of Coronary Artery Fistulas 50. Renal Artery Angioplasty and Stenting 50’: Renal denervation51. Iliac Angioplasty and Stenting 52. Endovascular Abdominal Aortic Aneurysm Repair 53. Carotid and Vertebral Artery Intervention Part 6. Complications and Management More case based54. Risk Stratification in Interventional Cardiology 55. Acute Threatened Coronary Closure 56. Subacute Closure 57. Coronary Artery Perforation 58. Embolization and No-Reflow During Percutaneous Coronary Intervention 59. Emergency Surgery 60. Complications of Peripheral Procedures 60’ Emergency resuscitation measuresPart 7. Medical Management of Risk Factors 61. Lipid-Lowering Therapy and the Interventional Cardiologist 62. Hypertension 63. Diabetes and Cardiovascular Disease 64. Nontraditional Risk Factors for AtherosclerosisPart 7’ Procedure selection (AUC and the “Heart Team”)64’ Appropriateness criteria for coronary revascularization 64’’ Appropriateness criteria for other procedures if there are anyPart 8. Preclinical and Clinical Trials 65. Preclinical Laboratory Functions 66. The Core Laboratory: Quantitative Coronary Angiography and Intravascular Ultrasound 67. How to Read Clinical Trials Part 9. Reimbursement and Hospital Finance 68. Cost-Effectiveness 69. Quality Assurance and Quality Improvement in Interventional Cardiology69’ ACO Part 10. Principles of Innovation 70. Innovation and Interventional Cardiology: Looking Back, Thinking Ahead 71. Principles of Innovation: Transforming Clinical Needs into Viable Inventions 71’’’ Regulatory considerations71’. Web based learning71’’. Web based clinical careIndex

Alan Yeung is the Co-Founder, President, and CEO of Where2Net, a provider of multi-channel software development tools and web applications. Dr. Yeung regularly speaks about wireless technologies and innovations at conference and seminars and is a guest lecturer at San Jose State University, where he teaches courses on Wireless Computing. Dr. Yeung received his MBA from University of California at Berkeley, his Ph.D. and MSChE from Stanford University, and a BSChE degree from University of Wisconsin. Spencer B. King, III, MD Director, Interventional Cardiology Emory University School of Medicine Atlanta, GA

• Part 1. Knowledge Foundation Section 1. Anatomy for Interventional Cardiology 1. Coronary Artery Anatomy for the Interventionalist, add some bypass anatomy? 2. Cardiac Chamber Anatomy (emphasize atrial septum and appendage)2’. Valve Anatomy (emphasize aortic and mitral)3. Peripheral Anatomy for the Interventionalist add radial (upper arm) anatomy Should we add carotid?Section 2. Physiology 4. The Coronary Circulation, emphasize FFR based concept 5. Physiological Evaluation of Renal Artery Stenosis: A Hemodynamic Approach5’. Sympathetic nervous system physiology (enphasize renal)Section 3. Pathophysiology 6. Valvular Pathophysiology 7. Arterial Disease Separate Coronary atherosclerosis from Arterial Disease8. Ventricular Pathophysiology Part 2. Equipment: Construction and Performance 9. Equipment for Percutaneous Coronary Intervention 10. Design and Construction of Stents 11. Adjunctive Devices: Atherectomy, Thrombectomy, Embolic Protections, IUVS, Doppler, and Pressure Wires11”. Aortic valvuloplasty equipment11’’: TAVR Equipment11’’’: ?Renal Dernervation equipment11’’’’ Closure devices11’’’’’Equiptment for structural heart disease interventions (ASD PFO etc) --This may precede TAVI, renal etcPart 3. Principles and Catheter Laboratory Equipment 12. X-Ray Cinefluorographic Systems 13. Operational Radiation Management for Patients and Staff 14. 15. X-Ray Computed Tomography and Magnetic Resonance Imaging of the Coronary Arteries 16. Intracardiac Echocardiography, OTC and FFR in the Catheterization Laboratory 17. Cardiac Catheterization Laboratory Physiologic Recorders 18. Digital Image Formats and Archiving Practices Part 4. Pharmacology Major update in content 19. Antithrombin Therapies 20. Antiplatelet Therapies in Contemporary Percutaneous Coronary Intervention 21. Thrombolytic Therapy 22. Radiographic Contrast Media 23. Renal Complications of Contrast Media 24. Patient Sedation in the Cardiovascular Catheterization Laboratory Part 5. Procedures 25. Diagnostic Procedures: Special Considerations25’ Radial Approach 26. Diagnostic Procedures: Peripheral Angiography 27. Adjunctive Diagnostic Techniques 28. Coronary Guidewire Manipulation 29. Coronary Balloon Angioplasty 30. Coronary Stenting, Bare Metal Stents, and Drug-Eluting Stents plus Bioabsorbable stents30’: Drug eluting balloon31. Rotational Atherectomy: Concepts and Practice 32” Instent restenosis 33. Basic Wire-Handling Strategies for Chronic Total Occlusion 34. Percutaneous Intervention in Chronic Total Coronary Occlusions 36. Distal Embolic Protection Devices 37. Intervention in Venous and Arterial Grafts 38. Special Considerations: Acute Myocardial Infarction 39. Complex Lesion Intervention: Bifurcation, Left Main Coronary Artery, and Ostial Lesions 40. Special Considerations: Small Vessel and Diffuse Disease 41. Special Patient Subsets: Diabetic and Elderly 42. Inoue-Balloon Mitral Valvuloplasty 43. Aortic Valvuloplasty and Future Solutions to Aortic Valve Disease44. Two TAVR techniques44. Balloon Pulmonary Valvuloplasty 44’Mitral clip44’’Atrial appendage closure45. Percutaneous Closure of Atrial Septal Defect and Patent Foramen Ovale 46. Alcohol Septal Ablation for Obstructive Hypertrophic Cardiomyopathy 47. Coronary Vein Device Insertion 48. Device Retrieval Systems 49. Percutaneous Treatment of Coronary Artery Fistulas 50. Renal Artery Angioplasty and Stenting 50’: Renal denervation51. Iliac Angioplasty and Stenting 52. Endovascular Abdominal Aortic Aneurysm Repair 53. Carotid and Vertebral Artery Intervention Part 6. Complications and Management More case based54. Risk Stratification in Interventional Cardiology 55. Acute Threatened Coronary Closure 56. Subacute Closure 57. Coronary Artery Perforation 58. Embolization and No-Reflow During Percutaneous Coronary Intervention 59. Emergency Surgery 60. Complications of Peripheral Procedures 60’ Emergency resuscitation measuresPart 7. Medical Management of Risk Factors 61. Lipid-Lowering Therapy and the Interventional Cardiologist 62. Hypertension 63. Diabetes and Cardiovascular Disease 64. Nontraditional Risk Factors for AtherosclerosisPart 7’ Procedure selection (AUC and the “Heart Team”)64’ Appropriateness criteria for coronary revascularization 64’’ Appropriateness criteria for other procedures if there are anyPart 8. Preclinical and Clinical Trials 65. Preclinical Laboratory Functions 66. The Core Laboratory: Quantitative Coronary Angiography and Intravascular Ultrasound 67. How to Read Clinical Trials Part 9. Reimbursement and Hospital Finance 68. Cost-Effectiveness 69. Quality Assurance and Quality Improvement in Interventional Cardiology69’ ACO Part 10. Principles of Innovation 70. Innovation and Interventional Cardiology: Looking Back, Thinking Ahead 71. Principles of Innovation: Transforming Clinical Needs into Viable Inventions 71’’’ Regulatory considerations71’. Web based learning71’’. Web based clinical careIndex