Fundamentals of Preparative and Nonlinear Chromatography

Inbunden, Engelska, 2006

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Beskrivning

Fundamentals of Preparative and Nonlinear Chromatography, Second Edition is devoted to the fundamentals of a new process of purification or extraction of chemicals or proteins widely used in the pharmaceutical industry and in preparative chromatography. This process permits the preparation of extremely pure compounds satisfying the requests of the US Food and Drug Administration. The book describes the fundamentals of thermodynamics, mass transfer kinetics, and flow through porous media that are relevant to chromatography. It presents the models used in chromatography and their solutions, discusses the applications made, describes the different processes used, their numerous applications, and the methods of optimization of the experimental conditions of this process.

Produktinformation

Utgivningsdatum:2006-02-10
Mått:170 x 246 x 42 mm
Vikt:1 900 g
Format:Inbunden
Språk:Engelska
Antal sidor:990
Upplaga:2
Förlag:Elsevier Science
ISBN:9780123705372

Utforska kategorier

Analytisk kemi inom Naturvetenskap och teknik

Mer om författaren

Professor Guiochon has been a Distinguished Scientist at the University of Tennessee and Oak Ridge National Laboratory since 1987. Born and educated in France, he was a Professor of chemistry at Ecole Polytechnique and at the University of Paris until 1984 when he moved to the USA. He has been working on nolinear and preparative chromatography since 1984. He has been awarded the 1978 Silver Medal of C.N.R.S.; Honarary Doctorates by the Technical University of Budapest (Hungary) in 1991 and by the University of Pardubice (Czech Republic) in 1999; the 1991 Separation Sciences Award and the 1998 Chromatography Award of the American Chemical Society; and the EAS Award in Separation Sciences in 2001. In 1994 he received an Alexander von Humboldt Award as a Senior American Scientist.

Innehållsförteckning

1. Introduction, Definitions, Goal2. The Mass Balance Equation of Chromatography and Its General Properties3. Single-Component Equilibrium Isotherms4. Competitive Equilibrium Isotherms5. Transfer Phenomena in Chromatography6. Linear Chromatography7. Band Profiles of Single-Components with the Ideal Model8. Band Profiles of Two Components with the Ideal Model9. Band Profiles in Displacement Chromatography with the Ideal Model10. Single-Component Profiles with the Equilibrium Dispersive Model11. Two-Component Band Profiles with the Equilibrium-Dispersive Model12. Frontal Analysis, Displacement and the Equilibrium-Dispersive Model13. System Peaks with the Equilibrium-Dispersive Model14. Kinetic Models and Single-Component Problems15. Gradient Elution Chromatography under Nonlinear Conditions16. Kinetic Models and Multicomponent Problems17. Simulated Moving Bed Chromatography18. Optimization of the Experimental Conditions