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    Annual Reports in Medicinal Chemistry

    AvJohn E. Macor

    Häftad, Engelska, 2008

    Del 43 i serien Annual Reports in Medicinal Chemistry

    1 827 kr

    Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

    Beskrivning

    Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies.

    • Covers findings related to cardiovascular, inflammation, and pulmonary diseases
    • Examines issues in oncology, from mTor inhibitors to drug targets
    • Incorporates up-to-date information on drug design and discovery, including delivery to market

    Produktinformation

    • Utgivningsdatum:2008-12-17
    • Mått:165 x 240 x undefined mm
    • Vikt:1 040 g
    • Format:Häftad
    • Språk:Engelska
    • Serie:Annual Reports in Medicinal Chemistry
    • Antal sidor:584
    • Förlag:Elsevier Science
    • ISBN:9780123743442

    Utforska kategorier

    • Tillverkningsteknik inom Naturvetenskap och teknik

    Innehållsförteckning

    • Part I. Central Nervous System Diseases ¨C ROBICHAUDChapter 1Recent Advances in Corticotropin Releasing Factor Receptor AntagonistsCarolyn D. Dzierba; Richard A. Hartz; Joanne J. BronsonChapter 2Recent Advances on the 5-HT5A, 5-HT6 and 5-HT7 ReceptorsBrock T. Shireman, Pascal Bonaventure and Nicholas I. CarruthersChapter 3Recent Advances in Voltage Gated Sodium Channel Blockers: Therapeutic Potential as Drug Targets in the CNSAndreas Termin, Esther Martinborough and Dean WilsonChapter 4Medication Development for the Treatment of Substance AbuseBrian Fulton Part II. Cardiovascular and Metabolic Diseases - STAMFORDChapter 5GPR40 (FFAR1) ModulatorsJulio C. Medina and Jonathan B. HouzeChapter 6Rho-Kinase Inhibitors for Cardiovascular DiseaseRobert A. StavengerChapter 7LXR Agonists for the Treatment of Atherosclerosis - Recent HighlightsJonathan Bennett, Andrew Cooke, Heather J. McKinnon and Olaf NimzChapter 8Glucagon Receptor Antagonists for Type II Diabetes DuaneE. DeMong, Michael W. Miller and Jean LachowiczPart III. Inflammation / Pulmonary / GI ¨C BARRISHChapter 9Advances Towards Dissociated Non-Steroidal Glucocorticoid Receptor AgonistsJohn Regan, Hossein Razavi, David ThomsonChapter 10Advances in the Discovery of IkB Kinase InhibitorsWilliam J. Pitts and James KempsonChapter 11Protease Inhibitors for the Potential Treatment of Chronic Obstructive Pulmonary Disease and Asthma Weimin Liu and Eugene HickeyPart IV. Oncology - MYLESChapter 12mTor Inhibitors in OncologyJeroen Verheijen, Ker Yu and Arie ZaskChapter 13Oncology Drug Targets in the Sphingomyelin Signaling PathBill Garland, Amy Cavalli and Genevi¨¨ve HansenPart V. Infectious Diseases - PrimeauChapter 14Inhibitors of Respiratory Syncytial Virus Malcolm Carter and G. Stuart Cockerill Chapter 15Recent Developments in ¦Â-Lactamases and InhibitorsTarek S. Mansour, Patricia A. Bradford and Aranapakam M. VenkatesanChapter 16Recent Development in the Treatment of Clostridium Difficile Associated Disease (CDAD)Xicheng Sun, Joseph Guiles and Nebojsa JanjicChapter 17Recent Advances in the Discovery of Hybrid Antibacterial AgentsMike BarbachynPart VI. Topics in Biology - LOWEChapter 18Recent Renaissance of Prostaglandin ResearchRobert BurkChapter 19Human Exposure and Dose ProjectionsPunit H. Marathe, Christine Huang and A. David RodriguesChapter 20Modeling Networks of Glycolysis, Overall Energy Metabolism and Drug Metabolism under a Systems Biology ApproachZoltan Sarnyai and Laszlo G. Boros Part VII. Topics in Drug Design and Discovery ¨C DESAIChapter 21Contrasting the Gastrointestinal Tracts of Mammals: Factors that Influence AbsorptionJohn DeSesso and Amy Lavin WilliamsChapter 22The Emerging Utility of Co-Crystals in Drug Discovery and DevelopmentNicholas MeanwellChapter 23Pregnane X Receptor: Prediction and Attenuation of Human CYP3A4 Enzyme Induction and Drug-Drug Interactions Michael W. SinzChapter 24Formulation in Drug Discovery Robert StrictlyPart VIII. To Market, To MarketChapter 25To Market, To Market - 2007Shridhar Hegde and Michelle Schmidt
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