Clusterin, Part B

Inbunden, Engelska, 2009

Del 105 i serien Advances in Cancer Research

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Beskrivning

The biological function of clusterin (CLU, also known as ApoJ, SGP2, TRPM2, CLI) has been puzzling researchers since its discovery and characterization in the early 1980s. Approaches such as cloning, expression and functional characterization of the different protein products generated by the CLU gene have now produced a critical mass of information of tremendous biological importance that are teaching us an important lesson in molecular biology of gene expression regulation. This volume brings together the contributions of top researchers in the field, providing an overview and synthesis of the latest thought and findings relating to CLU.

Produktinformation

Utgivningsdatum:2009-11-24
Mått:152 x 229 x undefined mm
Vikt:470 g
Format:Inbunden
Språk:Engelska
Serie:Advances in Cancer Research
Antal sidor:350
Förlag:Elsevier Science
ISBN:9780123814296

Utforska kategorier

Onkologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Recensioner i media

"This classic and essential series presents critical overviews on select aspects of both cancer research and the basic underlying sciences." -- American Scientist"Excellent, highly informative, in-depth reviews...expertly written, up-to-date, and well-referenced." --Journal of Medicinal Chemistry"This is a series that has a long tradition of excellence in the field of cancer biology." --Doody's Publishing Reviews

Innehållsförteckning

1. CLU and prostate cancer.S. Bettuzzi and F. Rizzi2. The role of Clusterin (CLU) in malignant transformation and drug resistance in breast carcinomas Maximino Redondo; Teresa Tellez; María Jose Roldan.3. CLU and COLON CANCERThe dual face of CLU: from normal to malignant phenotypeMazzarelli P. Pucci S. Spagnoli L.G.4. Clusterin (CLU) and lung cancerF. Panico*, 2F. Rizzi*, 1L.M. Fabbri, and 2S. Bettuzzi°, 1F. Luppi°5. CLUSTERIN AND CHEMORESISTANCEJulie Y. Djeu and Sheng Wei6. CLU "in and out": looking for a linkPucci S.1 , Mazzarelli P. 1 , Nucci C. 2, Ricci F. 2, Spagnoli L.G. 17. Regulation of CLU gene expression by oncogenes and epigeneticfactors: Implications for tumorigenesisArturo Sala, 2 * Saverio Bettuzzi, 3 Sabina Pucci, 1 Olesya Chayka, 4 Michael Dews, and 4 Andrei Thomas-Tikhonenko8. CONCLUSIONS AND PERSPECTIVESSaverio Bettuzzi