Oligomerization in Health and Disease

Dr.Jesús Giraldo currently teaches at Universitat Autònoma de Barcelona in Barcelona, Spain. Dr. Francisco Ciruela currently teaches at University of Barcelona, Barcelona, Spain.

Praise for the series:"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal

• Section I. Structural, Physico-Chemical, and Evolutionary Aspects of Protein Oligomerization Evolutionary, Physico-Chemical and Functional Mechanisms of Protein HomooligomerizationStructural, Evolutionary and Assembly Principles of Protein OligomerizationPhysico-Chemical Principles of Protein AggregationStructural Aspects of Amyloid FormationSection II. Oligomerization in Seven-Transmembrane ReceptorsQuaternary Structure Predictions and Structural Communication Features of GPCR DimersChallenges in the Development of Heteromer-GPCR-Based DrugsOligomerization of GPCRs in Health and Disease on "Di/Oligomerisation of GPCRS; Mechanisms and Functional Significance"G Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric DisordersDisease-Specific Heteromerization of G Protein-Coupled Receptors that Target Drugs of AbuseSection III. Oligomerization in Ion ChannelsSocial Networking among Voltage-Gated Potassium ChannelsOligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer TherapyConsequences of Dimerization of the Voltage Gated Proton ChannelReceptor Heteromeric Assembly, How it Works and Why it Matters - The Case of Ionotropic Glutamate ReceptorsSection IV. Oligomerization in EnzymesThe Structural Basis for the Allosteric Regulation of Ribonucleotide ReductaseOligomerization of Dynamin Superfamily Proteins in Health and DiseaseMultimerization of the Dnmt3a DNA Methyltransferase and its Functional ImplicationsOligomerization in Endoplasmic Reticulum Stress SignalingSection V. Oligomerization in Regulatory ProteinsToll-IL-1-Receptor-Containing Adaptor Molecule-1 (TICAM-1), a Signaling Adaptor Linking Innate Immunity to Adaptive ImmunityAssembly of Gamma-Tubulin Ring Complexes: Implications for Cell Biology and DiseaseChemokine Oligomerization in Cell Signaling and MigrationOligomerization of Rab/Effector Complexes in the Regulation of Vesicle Trafficking