Glycosylation and Cancer

• Utgivningsdatum: 2015-03-04
• Mått: 152 x 229 x 23 mm
• Vikt: 790 g
• Format: Inbunden
• Språk: Engelska
• Serie: Advances in Cancer Research
• Antal sidor: 418
• Förlag: Elsevier Science
• ISBN: 9780128013816

• Onkologi
• Medicinsk utrustning och medicinska tekniker

Dr. Drake is a Professor in the Department of Cell and Molecular Pharmacology and Experimental Therapeutics at the Medical University of South Carolina and SmartState Endowed Chair in Proteomics. He is an experienced protein biochemist and glycobiologist, with particular expertise in tumor biology and biomarker discovery from clinical fluids and tissues related to urological cancers and other cancers. He obtained his Ph.D. in Biochemistry at the University of Kentucky with Boyd Haley, generating multiple nucleotide sugar photoaffinity analogs for use in the study of glycosyltransferases. More extensive glycobiology training was done in post-doctoral work with Alan Elbein, and he began his academic career in Dr. Elbein’s department at the University of Arkansas for Medical Sciences. Currently, his research focus is on direct analysis of glycans and glycolipids in tissues using state-of-the-art MALDI mass spectrometry imaging approaches. Complementary glycopeptide mass spectrometry and metabolic labeling targeted approaches are being done to identify specific glycoproteins involved in the epithelial-to-mesenchymal transition.

Praise for the Serial"This classic and essential series presents critical overviews on select aspects of both cancerresearch and the basic underlying sciences." --American Scientist"Excellent, highly informative, in-depth reviews…expertly written, up-to-date, andwell-referenced." --Journal of Medicinal Chemistry"This is a series that has a long tradition of excellence in the field of cancer biology." --Doody’s Publishing Reviews

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