Systems Biology in Toxicology and Environmental Health

Dr. Rebecca Fry is an Associate Professor in the Department of Environmental Sciences and Engineering at the Gillings School of Global Public Health at UNC-Chapel Hill. She also holds appointments in the Curriculum in Toxicology and the Lineberger Cancer Center. She is the Deputy Director of UNC’s Superfund Research Program funded by the National Institute of Environmental Health Sciences (NIEHS). She also serves as the Director of Graduate Studies in the Curriculum of Toxicology and Co-PI of an NIEHS-funded T32 training grant. Dr. Fry received her B.S. in Biology from William Smith College. She received her M.S. and Ph.D. in Biology from Tulane University and completed her post-doctoral training at MIT. Her research focuses on unraveling the biological mechanisms by which prenatal exposures to toxic metals impact infant health. A primary goal of Dr. Fry’s research is to increase awareness of the deleterious impacts of exposures during the prenatal period and to improve public health initiatives to address this issue.

"...begins with a review of the biochemical basics of genomics and proteomics to establish a foundation for exploring applied examples of systems biology in environmental health and toxicology…Score: 70 - 3 Stars" --Doody's

• Chapter 1: Introduction to systems biologyChapter 2: Biology basicsChapter 3: From the genome to epigenome: fundamental conceptsChapter 4: Tools and technologies used in systems biologyChapter 5: Environmental contaminantsChapter 7: Environmental contaminants, inflammation-associated pathways and diseaseChapter 8: Environmental contaminants, apoptosis-associated pathways and diseaseChapter 9: Environmental contaminants, DNA damage and repair pathways and diseaseChapter 10: Environmental contaminants and hormone response and disease Chapter 11: The systems perspective