Biology and Engineering of Stem Cell Niches

Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matrix interactions.The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro.A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type.- Includes the importance of Cell-Cell and Cell Matrix Interactions in each specific tissue and system- Authored and edited by authorities in this emerging and multidisciplinary field- Includes valuable links to 5-10 minute YouTube© author videos that describe main points