Carlos Lopez-Otin is a Professor in the Biochemistry and Molecular Biology at the University of Oviedo, where he combines his teaching responsibilities with his research lines on Cancer and Aging Biology, as well as on the Functional Analysis of Genomes. His works have been collected in more than 350 articles in international journals and have been cited about 40,000 times to date. Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology.Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals:OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.

• 1. Mitochondria metabolism and agingMarina Vai2. MitohormesisPedro M. Quiros3. Mitochondrial dynamics in the aging stem cell compartmentRuth Slack4. Mitochondrial proteostasis and agingLuke Wiseman5. Mitochondrial DNA mutations and agingKonstanin Khrapko6. Mitochondrial sirtuins, NAD+, NADH and agingCarles Canto7. Mitophagy and agingNektarios Tavernarakis8. Mitochondria, calcium transport and agingPaolo Pinton