Human Reproductive Genetics

Juan García-Velasco is Director of IVI Madrid. He is also Professor of Obstetrics and Gynaecology at Rey Juan Carlos University, Madrid, Spain, where he is Director of their Master’s Degree Programme in Human Reproduction. He graduated from University Medical School, Madrid, in 1990 and received his Obstetrics and Gynecology certification from La Paz Hospital, Madrid, in 1995. He completed his PhD in Medicine from Autonoma University, Madrid, in 1995 and from 1997 to 1998 he studied at Yale University, New Haven, CT, under a Reproductive Endocrinology and Infertility Fellowship. His main research interests have been in IVF and endometriosis. He is the Principal Investigator of projects funded by the Ministry of Education and Ministry of Health, Spain, and has received awards from the Spanish Fertility Society, Spanish Society of Obstetrics and Gynecology, and the European Society of Human Reproduction and Embryology. He has published over 200 peer‐reviewed articles as well as 22 book chapters on human reproduction, endometriosis and hypo‐ and hyper‐ovarian stimulation response and is the author/editor of several books. Dr. Seli is Professor of Obstetrics, Gynecology, and Reproductive Sciences at Yale School of Medicine and Chief Scientific Officer at IVIRMA Global. He received his medical degree from the University of Istanbul and completed his Residency in Obstetrics and Gynecology at Yale University. His postdoctoral training included a fellowship in Reproductive Endocrinology and Infertility as well as a research fellowship in molecular biology, both at Yale University. As a physician-scientist, his primary focus is to understand and treat infertility. His laboratory characterized the mechanisms regulating translational activation of gene expression in the oocyte. Dr. Seli and his colleagues also made seminal contributions to our understanding of oocyte and embryo competence in IVF and the potential role of non-invasive diagnostic technologies in this context. Dr. Seli is the recipient of many National Institutes of Health (NIH) and pharmaceutical industry-sponsored research grants as well as numerous awards, including the Ira and Ester Rosenwaks New Investigator Award, American Society for Reproductive Medicine (ASRM) and the President’s Achievement Award from the Society for Reproductive Investigation (SRI).

"This is a wonderful first edition in a new and rapidly expanding field of human reproductive genetics. It is a useful book for its narrow-intended audience. It is an excellent resource for students, residents, and fellows. The wide range of contributors from across the globe adds to the book's fund of knowledge. I see this becoming an important resource to have in the future and I hope the authors will be able to keep it up to date given the evolving nature of the content." --Doody

• 1. Basic Genetics: Mitosis, Meiosis, Chromosomes, DNA, RNA and Beyond2. Identification of Genetic Causes of Gynecologic Disorders3. Cytogenetics4. Molecular biology approaches utilized in pre-implantation genetics: real time PCR, microarrays, next generation sequencing, karyomapping, and others5. Epigenetics and Imprinting In ART6. The Quest for Genetic Sequence Variants Conferring Risk of Endometriosis7. Genetics of PCOS8. Male Factor Infertility: Genetic and Epigenetic Aspects9. Mitochondrial Genetics10. Endometrial Receptivity and Genetics11. Genetics of Reproductive Aging and POF12. Prenatal Testing13. Carrier Testing in Reproductive Medicine14. PGT-A (PB, Day 3, Day 5…)15. Future Technologies for Pre-Implantation Genetic Applications16. Counseling: Psychology of Genetic Diagnoses17. Bioethics in Human Reproduction18. The Role of Genetic Counseling in the Infertile Patient