Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Dr. Prashant Kesharwani is an Assistant Professor of Pharmaceutics at Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, India. His work focuses on translational nanomedicine, polymeric biomaterials, targeted drug delivery, nanoengineered drug delivery systems, and translational pharmaceutical research. He has contributed extensively to the scientific literature and has served as an editor of scholarly books. Dr. Kesharwani has received research funding from national agencies and has been recognized with awards and fellowships for his contributions to the field. His research interests include nanomedicine, targeted and stimuli-responsive drug delivery, polymeric nanocarriers, and related pharmaceutical applications. He is actively involved in scientific research, academic mentoring, and scholarly publishing. Dr. Kishore M. Paknikar is Professor Agharkar Chair and former Director of Agharkar Research Institute, Pune, India. He is a MSc in Microbiology (1980) and a PhD in Microbiology (1984) from the University of Poona, India. His work in the field of delivery systems focuses on the delivery of drugs, proteins, peptides, siRNA, and nutrients. He is also exploring systems like polymeric nanoparticles and dendrimers for delivery of bioactive molecules in the treatment of cancers, Alzheimer’s disease, candidiasis, etc. He has more than 120 publications in highly reputed journals and 33 patents to his credit. He was a visiting Professor at Louis Pasteur University (Strasbourg, France) and Wayne State University (School of Medicine, Detroit, USA). He also worked as a Research Advisor at National Nanotechnology Centre (Ministry of Science and Technology), Bangkok, Thailand. He has several fellowships and awards to his credit. Dr. Virendra Gajbhiye has been working in the field of nanomedicine for the last 15 years. He has a doctoral degree (Ph.D.) in Pharmaceutical Science with post-doctoral research experience at University of Wisconsin-Madison and Oregon Health and Sciences University. Since 2013 he is working as a Scientist in Nanomedicine at Agharkar Research Institute, Pune, India. He has worked extensively with polymeric nanoparticles specially dendrimers and mesoporous silica nanoparticles. His research interest lies in Nanomedicine, Targeted drug and siRNA delivery, Biomedical application of dendrimers, Biomaterials unimolecular micelles and imaging, Multifunctional polymeric nanoparticles, Nanoparticles in tissue engineering.

• 1. Current status and future challenges of various polymers as cancer therapeutics2. An overview of polymeric nanoparticles as potential cancer therapeutics3. Poly acrylate (e.g., poly methylacrylate, poly ethyl acrylate, etc.) nanoparticles as promising tool for anticancer therapeutics4. Poly (alkyl cyano acrylate) nanoparticles as promising tool for anticancer therapeutics5. Poly (α-hydroxy acids) based nanoparticles for Drug/Gene delivery for cancer therapy6. Poly (ester), Poly hydroxy alkanoate nanoparticles as promising tool for anticancer therapeutics7. Poly (phospho ester), Poly (phosphazene) nanoparticles as promising tool for anticancer therapeutics8. Poly (carbonate) nanoparticles as promising tool for anticancer therapeutics9. Poly (amino acid) nanoparticles as promising tool for anticancer therapeutics10. Poly ethylene glycol nanoparticles as promising tool for anticancer therapeutics11. Dendrimer (polyamidoamine, polypropylene imine, poly-L-lysine, carbosilane dendrimers, triazine dendrimers) as promising tool for anticancer therapeutics12. Conjugated polymer nanoparticles as promising tool for anticancer therapeutics13. Microbes based natural polymer (Xanthum gum, alginate, gellan gum, carrageenan) nanoparticles as promising tool for anticancer therapeutics14. Plant based natural polymer (Guar gum, pectin, starch, cellulose, cyclodextrins) nanoparticles as promising tool for anticancer therapeutics15. Animal based natural polymer (Gelatin, chitosan, albumin, hyaluronic acid, chondroitin sulphate) nanoparticles as promising tool for anticancer therapeutics16. Polymersomes as promising tool for anticancer therapeutics17. Other polymers (Poly sulfonic acids, Poly carboxylic acids, Poly boronic acid, Poly silamine, etc.) nanoparticles as promising tool for anticancer therapeutics18. Conclusion and future prospective of polymeric nanoparticles as cancer therapeutics