Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors

Inbunden, Engelska, 2020

Del 169 i serien Progress in Molecular Biology and Translational Science

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Beskrivning

Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scienti?c importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine ?-synthase, and Oligomerization of Porphobilinogen Synthase.

Includes comprehensive coverage of molecular biology
Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided
Contains contributions from renowned experts in the field of molecular biology

Produktinformation

Utgivningsdatum:2020-01-17
Mått:152 x 229 x undefined mm
Vikt:720 g
Format:Inbunden
Språk:Engelska
Serie:Progress in Molecular Biology and Translational Science
Antal sidor:348
Förlag:Elsevier Science
ISBN:9780128179291

Utforska kategorier

Biokemi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik

Mer om författaren

Dr.Jesús Giraldo currently teaches at Universitat Autònoma de Barcelona in Barcelona, Spain. Dr. Francisco Ciruela currently teaches at University of Barcelona, Barcelona, Spain.

Recensioner i media

"This is a very important book that covers protein oligomerization in health and disease and provides essential knowledge of the oligomeric protein biology, which is critical to allow pharmacologic interventions in diseases associated with oligomeric protein malfunction. This is a unique book dedicated to fully explaining all about protein oligomerization." --Doody

Innehållsförteckning

1. Fluorescence microscopy methods for the study of protein oligomerizationRoberto Arturo Petazzi, Amit Koikkarah Aji and Salvatore Chiantia2. Computational prediction and redesign of aberrant protein oligomerizationJaime Santos, Valentín Iglesias and Salvador Ventura3. Porphobilinogen synthase: An equilibrium of different assemblies in human healthEileen K. Jaffe4. Prediction and targeting of GPCR oligomer interfacesCarlos A.V. Barreto, Salete J. Baptista, António José Preto, Pedro Matos-Filipe, Joana Mourão, Rita Melo and Irina Moreira5. Integrated structural modeling and super-resolution imaging resolve GPCR oligomersFrancesca Fanelli, Aylin C. Hanyaloglu and Kim Jonas6. Exploring functional consequences of GPCR oligomerization requires a different lensKyla Bourque, Jace Jones-Tabah, Dominic Devost, Paul B.S. Clarke and Terence E. Hébert7. Continuing challenges in targeting oligomeric GPCR-based drugsJoaquin Botta, Julia Appelhans and Peter J. McCormick8. Adenosine A2A-dopamine D2 receptor-receptor interaction in neurons and astrocytes: Evidence and perspectivesDiego Guidolin, Manuela Marcoli, Cinzia Tortorella, Guido Maura and L. Francesco Agnati9. Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug actionFaron-Górecka Agata, Kuśmider Maciej, Solich Joanna, Górecki Andrzej and Dziedzicka-Wasylewska Marta10. Oligomerization of G protein-coupled receptors: Still doubted?Sergi Ferré, Francisco Ciruela, Vicent Casadó and Leonardo Pardo