New Frontiers and Applications of Synthetic Biology

Häftad, Engelska, 2022

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Beskrivning

New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more.

This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas.

Offers basic understanding and knowledge in several aspects of synthetic biology
Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more
Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more

Produktinformation

Utgivningsdatum:2022-01-19
Mått:216 x 276 x undefined mm
Vikt:1 250 g
Format:Häftad
Språk:Engelska
Antal sidor:486
Förlag:Elsevier Science
ISBN:9780128244692

Utforska kategorier

Biologi inom Naturvetenskap och teknik

Mer om författaren

Prof. Vijai Singh is currently serving as Head of the Department of Biosciences, School of Science and Dean (Research & Innovation) at Indrashil University, Rajpur, Mehsana, India. Prior to this, he held the position of Associate Professor in the same department at Indrashil University. He has also served as Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, and in the Department of Biotechnology at the Invertis University, Bareilly, India. Earlier of his career, Prof. Singh worked as a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and at the School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He earned his Ph.D. in Biotechnology in 2009 from the ICAR-National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India. His doctoral research focused on the development of molecular and immunoassays for the diagnosis of Aeromonas hydrophila. Prof. Singh’s research interests lies in the design and construction of novel biosynthetic pathways for production of medically and industrially important biomolecules. His laboratory is also actively engaged in developing CRISPR-Cas systems for gene knock out, knock in, gene regulation and diagnostic. With over 15 years of research and teaching experience, his areas of expertise include synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has an extensive academic record, with over 110 articles, 89 book chapters, 26 books and 3 patents to his credits. Prof. Singh has received number of prestigious awards, including the Bioclues Innovation, Research and Development Award (2023) from the BIOCLUES Society, the Vice Chancellor's Best Research Award (2023) from Indrashil University, and the Agathiyar Chemical Biology Award (2023) from the Society of Chemical and Synthetic Biology. At Indrashil University, he currently serves as chairman of the Board of Study, and is a member of the Academic Council of Indrashil University. He also holds the position of the Member Secretary of the Institutional Biosafety Committee (IBSC) at the university. Dr. Singh is actively involved in national and international scientific advisory roles.

Innehållsförteckning

1. An introduction to advanced technologies in synthetic biologyVijai Singh, Gargi Bhattacharjee, Nisarg Gohil, Rupesh Maurya, Navya L. Lam and Khalid J. Alzahrani2. Design and characterization of synthetic promotersBoris Kirov and Slavil Peykov3. Recent development in DNA synthesis technologyIndra Mani4. Advances, challenges, and opportunities in DNA sequencing technologyFrancisco J. Enguita and Ana Lucia Leitao5. Recent developments in genome design and assembly toolsCarlos Barreiro and Carlos Garcıa-Estrada6. Design, building, and challenges in synthetic genomicsMansoor A. Siddiqui, Ashima Sharma and Syed Shams Yazdani7. Synthetic minimal cells and their applicationsAli Yazdizadeh Kharrazi, Amir Zare, Nils Chapin, Seyedkhashayar Ghavami and Amir Pandi8. Small RNA-based systems for sensing and therapeutic applicationsRobert Penchovsky, Georgi Y. Miloshev, Nikolet Pavlova, Katya B. Popova, Aikaterini Valsamatzi-Panagiotou, Lozena A. Otcheva and Martina Traykovska9. High-throughput navigation of the sequence spaceAlaksh Choudhury10. Advances in protein engineering and its application in synthetic biologyRongming Liu, Liya Liang, Maria Priscila Lacerda, Emily F. Freed and Carrie A. Eckert11. Computational tools for design of synthetic genetic circuitsArchit Devarajan, Dhwani Gupta, Kushika Mitra, Shalini S. Deb and Shamlan M.S. Reshamwala12. Computational tools for synthetic gene optimizationNumaan Cheema, Georgios Papamichail and Dimitris Papamichail13. De novo design and synthesis of biomoleculesSubha Sankar Paul, Debarun Dhali, Yazen Yaseen, Upasana Basu, Shilpa Pal, Nihal Mohammed and Heykel Trabelsi14. A retrobiosynthetic approach for production, conversion, sensing, dynamic regulation and degradation of moleculesPablo Carbonell15. Advances in engineering of bacteriophages for therapeutic applicationsChristian Møller-Olsen, Gurneet K. Dhanoa, Tamas Feher and Antonia P. Sagona16. Design of synthetic biology for the detection of microorganismsDong-Dong Yang, Jake Flood, Rongming Liu and Susu He17. Design of synthetic biological devices for detection and targeting human diseasesNedim Haciosmanoglu, Sıla Kose, Julian Ostaku, Ilkay Cisil Koksaldi, Behide Saltepe and Urartu Ozgur Safak Seker18. Engineering cell-based therapiesJuan Luis Blazquez-Roman, Mara Pisani and Velia Siciliano19. Development of next-generation diagnostic tools using synthetic biologyElizabeth J. Vojvoda, Logan R. Burrington and Javin P. Oza20. Advances and application of CRISPR-Cas systemsRongming Liu, Liya Liang, Margaret Habib, Emily F. Freed and Carrie A. Eckert21. Synthetic biology for smart drug biosynthesis and deliverySrinivasan Ganesh Kumar, Ashok Ganesan and Shashi Kumar22. Design and applications of self-assembled soft living materials using synthetic biologyGokce Ozkul, Merve Yavuz, Nedim Hacıosmanoglu, Busra Merve Kırpat and Urartu Ozgur Safak Seker23. Synthetic gene circuits for higher-order information processingKathakali Sarkar and Sangram Bagh24. Cell-free synthetic biology as an emerging biotechnologySeok Hoon Hong and Ana Serratosa Fernandez-Baca25. Recent development and applications of xeno nucleic acidsRupesh Maurya, Nisarg Gohil, Gargi Bhattacharjee, Navya L. Lam, Khalid J. Alzahrani and Vijai Singh26. Developments in the use of microfluidics in synthetic biologyLaila A. Damiati, Safa A. Damiati and Samar Damiati27. Implications of synthetic biology research and development: a structured ethical analysisKevin Smith