this book achieves a balance between clinical topics which will appeal to all practising nephrologists, and more fundamental aspects of amyloidosis which will interest anyone trying to unravel this challenging disorder.

• Part I: General aspects of amyloidosios ; 1. Pathpophysiology of amyloidogenesis ; 2. Various clinical types of amyloidosis ; Part II: Clinical characteristics of *B2=microglobulin amyloidosis ; 3. Arthropathy and carpal tunnel syndrome of *B2-microglobulin amyloidosis ; 4. Radiology of dialysis amyloidosis ; 5. Ultrasonography of the joints ; 6. Whole-body scintigraphy ; Part III: Pathology of *B2-microglobulin deposits ; 7. Composition of *B2-microglobulin deposits ; 8. Description, localization, and progression of B2-microglobulin dialysis-related amyloid deposition ; Part IV: Physiopathology of *B2-microglobulin accumulation and deposition ; 9. Characteristics of *B2-microglobulin metabolism ; 10. Involvement of *B2- microglobulin modified with AGEs in dialysis-related amyloidosis ; 11. Factors modifying removal and production of *B2-microglobulin ; 12. Determinants of fibril precipitation and aggregation in amyloid deposits. ; Part IV: Review of the clinical evidence on the prophylactic and therapeutic approaches to *B2-microglobulin amyloidosis ; 13. Prevention and treatment of *B2-microglobulin amyloidosis

this book achieves a balance between clinical topics which will appeal to all practising nephrologists, and more fundamental aspects of amyloidosis which will interest anyone trying to unravel this challenging disorder.

• Part I: General aspects of amyloidosios ; 1. Pathpophysiology of amyloidogenesis ; 2. Various clinical types of amyloidosis ; Part II: Clinical characteristics of *B2=microglobulin amyloidosis ; 3. Arthropathy and carpal tunnel syndrome of *B2-microglobulin amyloidosis ; 4. Radiology of dialysis amyloidosis ; 5. Ultrasonography of the joints ; 6. Whole-body scintigraphy ; Part III: Pathology of *B2-microglobulin deposits ; 7. Composition of *B2-microglobulin deposits ; 8. Description, localization, and progression of B2-microglobulin dialysis-related amyloid deposition ; Part IV: Physiopathology of *B2-microglobulin accumulation and deposition ; 9. Characteristics of *B2-microglobulin metabolism ; 10. Involvement of *B2- microglobulin modified with AGEs in dialysis-related amyloidosis ; 11. Factors modifying removal and production of *B2-microglobulin ; 12. Determinants of fibril precipitation and aggregation in amyloid deposits. ; Part IV: Review of the clinical evidence on the prophylactic and therapeutic approaches to *B2-microglobulin amyloidosis ; 13. Prevention and treatment of *B2-microglobulin amyloidosis

this book achieves a balance between clinical topics which will appeal to all practising nephrologists, and more fundamental aspects of amyloidosis which will interest anyone trying to unravel this challenging disorder.

• Part I: General aspects of amyloidosios ; 1. Pathpophysiology of amyloidogenesis ; 2. Various clinical types of amyloidosis ; Part II: Clinical characteristics of *B2=microglobulin amyloidosis ; 3. Arthropathy and carpal tunnel syndrome of *B2-microglobulin amyloidosis ; 4. Radiology of dialysis amyloidosis ; 5. Ultrasonography of the joints ; 6. Whole-body scintigraphy ; Part III: Pathology of *B2-microglobulin deposits ; 7. Composition of *B2-microglobulin deposits ; 8. Description, localization, and progression of B2-microglobulin dialysis-related amyloid deposition ; Part IV: Physiopathology of *B2-microglobulin accumulation and deposition ; 9. Characteristics of *B2-microglobulin metabolism ; 10. Involvement of *B2- microglobulin modified with AGEs in dialysis-related amyloidosis ; 11. Factors modifying removal and production of *B2-microglobulin ; 12. Determinants of fibril precipitation and aggregation in amyloid deposits. ; Part IV: Review of the clinical evidence on the prophylactic and therapeutic approaches to *B2-microglobulin amyloidosis ; 13. Prevention and treatment of *B2-microglobulin amyloidosis