Helmut Kettenmann, PhD, Research Group Leader, Cellular Neurosciences, Max-Delbrück-Centrum for Molecular Neuroscience, Berlin, Germany. Bruce R. Ransom, MD, PhD, Warren and Jermaine Magnuson Professor and Chair, Department of Neurology, University of Washington School of Medicine, Seattle, WA

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• Foreword to Ed. 3 ; Introduction ; Section 1. Properties of Neuroglial Cells ; Evolution of glial cells: insights from invertebrate glia ; 1 Evolution of glial cells, Christian Klambt ; 2 Invertebrate glia, Marc R. Freeman ; 3 Non-mammalian, vertebrate glia, Bruce Appel ; Morphology, Ultrastructure and Identification ; 4 ASTROCYTES AND EPENDYMAL GLIA, Andreas Reichenbach and Hartwig Wolburg ; 5 Radial glial cells, Magdalena Gotz ; 6 STRUCTURE AND FUNCTION OF OLIGODENDROCYTES, Arthur M. Butt ; 7 Schwann cells and myelin, by Rudolf Martini and Agnes Patzko ; 8 Microglial Cells, Wolfgang J. Streit ; 9 Pericytes of the central nervous system, Martin Krueger and Ingo Bechmann ; 10 NG2 Cells (Polydendrocytes), Akiko Nishiyama ; 11 Glial Cells in autonomic and sensory ganglia, Menachem Hanani and David C. Spray ; Lineage and development ; 12 Astrocyte Development, James E. Goldman ; 13 Lineage and development: Oligodendrocytes, Katsuhiko Ono and Kazuhiro Ikenaka ; 14 THE SCHWANN CELL LINEAGE: CELLULAR TRANSITIONS DURING DEVELOPMENT AND AFTER INJURY, Kristjan R.Jessen and Rhona Mirsky ; 15 MICROGLIA LINEAGE AND DEVELOPMENT, Marco Prinz ; Physiological Properties ; 16 Physiology of astrocytes: Ion channels and ion transporters, Christian Steinhauser, Gerald Seifert, and Joachim W. Deitmer ; 17 Release of gliotransmitters and transmitter receptors in astrocytes, Helmut Kettenmann and Robert Zorec ; 18 Storage and release of non-transmitter signaling molecules from macroglia, OLIVER VON BOHLEN UND HALBACH AND KLAUS UNSICKER ; 19 Physiology of microglia, Mami Noda & Alexei Verkhratsky ; 20 Physiology of Oligodendrocytes, Vittorio Gallo and Jean-Marie Mangin ; 21 Physiological Properties of NG2+ Glial Cells, Dwight E. Bergles ; 22 Cytokine, chemokine and growth factor receptors and signaling, H.W.G.M. Boddeke, B.J.L. Eggen, and K.P.H. Biber ; 23 Lipids, lipid mediators and other signaling molecules, Hideki Hayashi ; 24 Gap Junctions and Hemichannels, Bruce R. Ransom and Christian Giaume ; 25 Purinergic Mechanisms in Glial Cells, Margaret S. Ho and Shumin Duan ; 26 Calcium signalling in neuroglia, Alexei Verkhratsky & Vladimir Parpura ; 27 The Central Role of Astrocytes in Neuroenergetics, Pierre J. Magistretti and Luc Pellerin ; Genomic Profiles ; 28 The Astrocyte Transcriptome, Ditte Lovatt and Maiken Nedergaard ; 29 Gene expression patterns of oligodendrocyte progenitor cells and oligodendroglia, Fraser J. Sim and Steven A. Goldman ; Section 2. Functions of Neuroglial Cells ; Astrocytes ; 30 Outer Subventricular Zone Radial Glial Cells, Xiaoqun Wang and Arnold R. Kriegstein ; 31 Glial control of synaptogenesis, Nicola J. Allen ; 32 Neuron Migration and Axon Guidance, Andreas Faissner ; 33 The Role of Glia in the Formation and Function of the Blood-Brain Barrier, Istvan Krizbai, Imola Wilhelm, Hans-Christian Bauer and Hannelore Bauer ; 34 Control of the extracellular ionic environment and volume, Eva Sykova ; 35 Amino Acid Neurotransmitter Synthesis and Removal, Arne Schousboe, Lasse K. Bak, Karsten K. Madsen and Helle S. Waagepetersen ; 36 Glycogen and Energy Metabolism, Angus Brown ; 37 Astrocyte regulation of neurovascular control, Clare Howarth, Grant R.J. Gordon and Brian A. MacVicar ; 38 Modulation of synaptic function and network activity, Andrea Volterra ; 39 Astrocytic modulation of mammalian synapses circuits and behaviors, Michael M. Halassa and Philip G. Haydon ; 40 Adult neurogenesis, Gerd Kempermann ; 41 Modulation of neuroendocrine systems, Stephane H. R. Oliet ; Oligodendrocytes/Schwann cells ; 42 Myelin, Impulse Conduction, and the Pathophysiology of Demyelination, Lakshmi Bangalore and Stephen G. Waxman ; 43 Transcription factors in myelinating cells, Michael Wegner ; 44 Factors controlling myelin formation , Ruth Stassart, Sandra Goebbels, Klaus-Armin Nave ; 45 Regulation of Myelination by Functional Activity, R. Douglas Fields ; 46 Iron and Glia, James R. Connor ; Microglia ; 47 Role of microglia in the normal brain, Frank Kirchhoff ; 48 Factors controlling microglial activation, Uwe-Karsten Hanisch ; 49 Roles of activated microglia, Kelly R Miller, Stefan Prokop & Frank L Heppner ; 50 Immune functions of microglia, Trevor Owens ; Section 3. Role of glial cells in disease ; Mechanisms of glial injury ; 51 Astrocyte Responses to CNS Injury and Disease, Michael V. Sofroniew ; 52 Metabolic injury of oligodendrocytes and myelin, Peter K. Stys ; 53 Interaction of microglia with neurons and astrocytes under lesioned neuronal conditions, Kazuyuki Nakajima and Shinichi Kohsaka ; 54 Schwann cells and injury, Violetta Zujovic and Alexandros A. Lavdas ; Recovery of Neural Function ; 55 NERVE REGENERATION IN THE PERIPHERAL NERVOUS SYSTEm, Tessa Gordon and Olawale AR Sulaiman ; 56 Nerve fibre regeneration in the CNS of higher vertebrates, Anita D. Buchli and, Martin E. Schwab ; 57 GLIAL CELL TRANSPLANTATION FOR CNS REPAIR, Anne Baron-Van Evercooren and Rebecca Matsas ; Diseases: ; 58 Focal cerebral ischemia: The multifaceted role of glial cells, Ulrich Dirnagl, Bruce R. Ransom, and Josef Priller ; Gliomas: ; 59 Malignant Glioma, Dolores Hambardzumyan, Shannon Donnola and Rebecca Bish ; 60 Glial tumors in Neurofibromatosis and Tuberous Sclerosis Complex, Anthony J. Apicelli and David H. Gutmann ; Demyelinating diseases ; 61 Multiple Sclerosis, Monika Bradl and Hans Lassmann ; 62 Genetic mutations affecting myelin formation, Steven S. Scherer, M. Laura Feltri, and Lawrence Wrabetz ; Neurodegenerative Diseases ; 63 Amyotrophic Lateral Sclerosis (ALS), Rita Sattler and Jeffrey Rothstein ; 64 Alzheimer's disease, Andrew Kraft and Jin-Moo Lee ; 65 Huntington disease, Parkinson disease and other neurodegenerative diseases, Thomas Moller ; Infectious diseases ; 66 Glia in Bacterial and Viral CNS Infections, Gwenn Garden ; Miscellaneous diseases 67 Neuroglia in Hepatic Encephalopathy, Mireille Belanger, Javier Vaquero, and Roger F. Butterworth ; 68 Microglia and Pain, Simon Beggs, Tuan Trang and Michael W. Salter ; 69 Genetic disorders affecting astrocytes, Albee Messing and Michael Brenner ; 70 Epilepsy, Detlev Boison ; 71 Psychiatric Disorders, Josef Priller

Helmut Kettenmann, PhD, Research Group Leader, Cellular Neurosciences, Max-Delbrück-Centrum for Molecular Neuroscience, Berlin, Germany. Bruce R. Ransom, MD, PhD, Warren and Jermaine Magnuson Professor and Chair, Department of Neurology, University of Washington School of Medicine, Seattle, WA

Select Guide Rating

• Foreword to Ed. 3 ; Introduction ; Section 1. Properties of Neuroglial Cells ; Evolution of glial cells: insights from invertebrate glia ; 1 Evolution of glial cells, Christian Klambt ; 2 Invertebrate glia, Marc R. Freeman ; 3 Non-mammalian, vertebrate glia, Bruce Appel ; Morphology, Ultrastructure and Identification ; 4 ASTROCYTES AND EPENDYMAL GLIA, Andreas Reichenbach and Hartwig Wolburg ; 5 Radial glial cells, Magdalena Gotz ; 6 STRUCTURE AND FUNCTION OF OLIGODENDROCYTES, Arthur M. Butt ; 7 Schwann cells and myelin, by Rudolf Martini and Agnes Patzko ; 8 Microglial Cells, Wolfgang J. Streit ; 9 Pericytes of the central nervous system, Martin Krueger and Ingo Bechmann ; 10 NG2 Cells (Polydendrocytes), Akiko Nishiyama ; 11 Glial Cells in autonomic and sensory ganglia, Menachem Hanani and David C. Spray ; Lineage and development ; 12 Astrocyte Development, James E. Goldman ; 13 Lineage and development: Oligodendrocytes, Katsuhiko Ono and Kazuhiro Ikenaka ; 14 THE SCHWANN CELL LINEAGE: CELLULAR TRANSITIONS DURING DEVELOPMENT AND AFTER INJURY, Kristjan R.Jessen and Rhona Mirsky ; 15 MICROGLIA LINEAGE AND DEVELOPMENT, Marco Prinz ; Physiological Properties ; 16 Physiology of astrocytes: Ion channels and ion transporters, Christian Steinhauser, Gerald Seifert, and Joachim W. Deitmer ; 17 Release of gliotransmitters and transmitter receptors in astrocytes, Helmut Kettenmann and Robert Zorec ; 18 Storage and release of non-transmitter signaling molecules from macroglia, OLIVER VON BOHLEN UND HALBACH AND KLAUS UNSICKER ; 19 Physiology of microglia, Mami Noda & Alexei Verkhratsky ; 20 Physiology of Oligodendrocytes, Vittorio Gallo and Jean-Marie Mangin ; 21 Physiological Properties of NG2+ Glial Cells, Dwight E. Bergles ; 22 Cytokine, chemokine and growth factor receptors and signaling, H.W.G.M. Boddeke, B.J.L. Eggen, and K.P.H. Biber ; 23 Lipids, lipid mediators and other signaling molecules, Hideki Hayashi ; 24 Gap Junctions and Hemichannels, Bruce R. Ransom and Christian Giaume ; 25 Purinergic Mechanisms in Glial Cells, Margaret S. Ho and Shumin Duan ; 26 Calcium signalling in neuroglia, Alexei Verkhratsky & Vladimir Parpura ; 27 The Central Role of Astrocytes in Neuroenergetics, Pierre J. Magistretti and Luc Pellerin ; Genomic Profiles ; 28 The Astrocyte Transcriptome, Ditte Lovatt and Maiken Nedergaard ; 29 Gene expression patterns of oligodendrocyte progenitor cells and oligodendroglia, Fraser J. Sim and Steven A. Goldman ; Section 2. Functions of Neuroglial Cells ; Astrocytes ; 30 Outer Subventricular Zone Radial Glial Cells, Xiaoqun Wang and Arnold R. Kriegstein ; 31 Glial control of synaptogenesis, Nicola J. Allen ; 32 Neuron Migration and Axon Guidance, Andreas Faissner ; 33 The Role of Glia in the Formation and Function of the Blood-Brain Barrier, Istvan Krizbai, Imola Wilhelm, Hans-Christian Bauer and Hannelore Bauer ; 34 Control of the extracellular ionic environment and volume, Eva Sykova ; 35 Amino Acid Neurotransmitter Synthesis and Removal, Arne Schousboe, Lasse K. Bak, Karsten K. Madsen and Helle S. Waagepetersen ; 36 Glycogen and Energy Metabolism, Angus Brown ; 37 Astrocyte regulation of neurovascular control, Clare Howarth, Grant R.J. Gordon and Brian A. MacVicar ; 38 Modulation of synaptic function and network activity, Andrea Volterra ; 39 Astrocytic modulation of mammalian synapses circuits and behaviors, Michael M. Halassa and Philip G. Haydon ; 40 Adult neurogenesis, Gerd Kempermann ; 41 Modulation of neuroendocrine systems, Stephane H. R. Oliet ; Oligodendrocytes/Schwann cells ; 42 Myelin, Impulse Conduction, and the Pathophysiology of Demyelination, Lakshmi Bangalore and Stephen G. Waxman ; 43 Transcription factors in myelinating cells, Michael Wegner ; 44 Factors controlling myelin formation , Ruth Stassart, Sandra Goebbels, Klaus-Armin Nave ; 45 Regulation of Myelination by Functional Activity, R. Douglas Fields ; 46 Iron and Glia, James R. Connor ; Microglia ; 47 Role of microglia in the normal brain, Frank Kirchhoff ; 48 Factors controlling microglial activation, Uwe-Karsten Hanisch ; 49 Roles of activated microglia, Kelly R Miller, Stefan Prokop & Frank L Heppner ; 50 Immune functions of microglia, Trevor Owens ; Section 3. Role of glial cells in disease ; Mechanisms of glial injury ; 51 Astrocyte Responses to CNS Injury and Disease, Michael V. Sofroniew ; 52 Metabolic injury of oligodendrocytes and myelin, Peter K. Stys ; 53 Interaction of microglia with neurons and astrocytes under lesioned neuronal conditions, Kazuyuki Nakajima and Shinichi Kohsaka ; 54 Schwann cells and injury, Violetta Zujovic and Alexandros A. Lavdas ; Recovery of Neural Function ; 55 NERVE REGENERATION IN THE PERIPHERAL NERVOUS SYSTEm, Tessa Gordon and Olawale AR Sulaiman ; 56 Nerve fibre regeneration in the CNS of higher vertebrates, Anita D. Buchli and, Martin E. Schwab ; 57 GLIAL CELL TRANSPLANTATION FOR CNS REPAIR, Anne Baron-Van Evercooren and Rebecca Matsas ; Diseases: ; 58 Focal cerebral ischemia: The multifaceted role of glial cells, Ulrich Dirnagl, Bruce R. Ransom, and Josef Priller ; Gliomas: ; 59 Malignant Glioma, Dolores Hambardzumyan, Shannon Donnola and Rebecca Bish ; 60 Glial tumors in Neurofibromatosis and Tuberous Sclerosis Complex, Anthony J. Apicelli and David H. Gutmann ; Demyelinating diseases ; 61 Multiple Sclerosis, Monika Bradl and Hans Lassmann ; 62 Genetic mutations affecting myelin formation, Steven S. Scherer, M. Laura Feltri, and Lawrence Wrabetz ; Neurodegenerative Diseases ; 63 Amyotrophic Lateral Sclerosis (ALS), Rita Sattler and Jeffrey Rothstein ; 64 Alzheimer's disease, Andrew Kraft and Jin-Moo Lee ; 65 Huntington disease, Parkinson disease and other neurodegenerative diseases, Thomas Moller ; Infectious diseases ; 66 Glia in Bacterial and Viral CNS Infections, Gwenn Garden ; Miscellaneous diseases 67 Neuroglia in Hepatic Encephalopathy, Mireille Belanger, Javier Vaquero, and Roger F. Butterworth ; 68 Microglia and Pain, Simon Beggs, Tuan Trang and Michael W. Salter ; 69 Genetic disorders affecting astrocytes, Albee Messing and Michael Brenner ; 70 Epilepsy, Detlev Boison ; 71 Psychiatric Disorders, Josef Priller