Alexander W. Clowes (1946–2015), vascular surgeon, internationally renowned scientist in vascular biology, teacher and mentor, held the Gavora-Schilling Endowed Chair of Vascular Surgery at the University of Washington School of Medicine. Clowes was a Director and President of The Clowes Fund.

"The book is written in a clear but engaging manner, neither fawning nor clinical. Readers should find it informative and enlightening, showing the personal lives behind some very public endeavors."—The Franklin Daily Journal"The Doc and the Duchess is . . . a labor of love and yet another treasure that the Clowes family has bequeathed to the Indianapolis community."—Indiana Magazine of History"The Doc and the Duchess is a must-read for anyone interested in drug development, medical history, and diabetes. Clowes gives us a thorough, compelling, and important book, offering unprecedented insight into his grandfather, whose extraordinary gift for inspiring scientists to work together long predated modern concepts of networking and teambuilding.  The letters, interviews, and family lore illuminate an original thinker with a personality as irresistible on the page as it must have been in person."—Thea Cooper, author of Breakthrough: Elizabeth Hughes, the Discovery of Insulin, and the Making of a Medical Mira"This well-researched book celebrates the lives of George H. A. and Edith Clowes. GHA Clowes' advanced research made Eli Lilly and Company a world leader in the development of insulin and played a critical role in Lilly's development into a global pharmaceutical company."—Michael Bliss, author of The Discovery of Insulin"Vividly told, the book captures the personalities of the protagonists, contains scientifically sophisticated explanations about the development of marketable insulin, and invokes the evolving environment—economic, medical, social, and familial—in which the story takes place."—Strobe Talbott, author of The Great Experiment"This is a fascinating story about an incredible man, his wife, and his family.  Everyone interested in the early days after the discovery of insulin will want to read this book."—Irl B. Hirsch, M.D., Professor of Medicine and Diabetes Treatment and Teaching Chair, University of Washington Scho"A delight to read—well written and authoritative. This is an insider's story, lovingly told."—Leonard Warren, author of Maclure of New Harmony

• Foreword / John LechleiterAcknowledgementsIntroduction: A Warm Embrace1. Growing Up in Victorian England2. The Search for a Cure of Cancer3. Edith Whitehill Hinkel 4. Alec and Edith5. 1914: The End of an Era6. In the Borderline Fields of Medicine 7. Lilly and the Insulin Story8. From Small to Large Scale Production of Insulin9. Expansion of the Research Programs10. Woods Hole, MBL, and the Pursuit of Cancer11. The Duchess, The Doc and The Boys12. Alec and Edith: Indianapolis Benefactors13. A Legacy: In Others' EyesAppendix I: Publications of George Henry Alexander ClowesAppendix II: Chronology of Ancestry NotesWorks CitedIndex

Alexander W. Clowes (1946–2015), vascular surgeon, internationally renowned scientist in vascular biology, teacher and mentor, held the Gavora-Schilling Endowed Chair of Vascular Surgery at the University of Washington School of Medicine. Clowes was a Director and President of The Clowes Fund.

"The book is written in a clear but engaging manner, neither fawning nor clinical. Readers should find it informative and enlightening, showing the personal lives behind some very public endeavors."—The Franklin Daily Journal"The Doc and the Duchess is . . . a labor of love and yet another treasure that the Clowes family has bequeathed to the Indianapolis community."—Indiana Magazine of History"The Doc and the Duchess is a must-read for anyone interested in drug development, medical history, and diabetes. Clowes gives us a thorough, compelling, and important book, offering unprecedented insight into his grandfather, whose extraordinary gift for inspiring scientists to work together long predated modern concepts of networking and teambuilding.  The letters, interviews, and family lore illuminate an original thinker with a personality as irresistible on the page as it must have been in person."—Thea Cooper, author of Breakthrough: Elizabeth Hughes, the Discovery of Insulin, and the Making of a Medical Mira"This well-researched book celebrates the lives of George H. A. and Edith Clowes. GHA Clowes' advanced research made Eli Lilly and Company a world leader in the development of insulin and played a critical role in Lilly's development into a global pharmaceutical company."—Michael Bliss, author of The Discovery of Insulin"Vividly told, the book captures the personalities of the protagonists, contains scientifically sophisticated explanations about the development of marketable insulin, and invokes the evolving environment—economic, medical, social, and familial—in which the story takes place."—Strobe Talbott, author of The Great Experiment"This is a fascinating story about an incredible man, his wife, and his family.  Everyone interested in the early days after the discovery of insulin will want to read this book."—Irl B. Hirsch, M.D., Professor of Medicine and Diabetes Treatment and Teaching Chair, University of Washington Scho"A delight to read—well written and authoritative. This is an insider's story, lovingly told."—Leonard Warren, author of Maclure of New Harmony

• Foreword / John LechleiterAcknowledgementsIntroduction: A Warm Embrace1. Growing Up in Victorian England2. The Search for a Cure of Cancer3. Edith Whitehill Hinkel 4. Alec and Edith5. 1914: The End of an Era6. In the Borderline Fields of Medicine 7. Lilly and the Insulin Story8. From Small to Large Scale Production of Insulin9. Expansion of the Research Programs10. Woods Hole, MBL, and the Pursuit of Cancer11. The Duchess, The Doc and The Boys12. Alec and Edith: Indianapolis Benefactors13. A Legacy: In Others' EyesAppendix I: Publications of George Henry Alexander ClowesAppendix II: Chronology of Ancestry NotesWorks CitedIndex