Committee on the Basic Science Foundations of Medically Assisted Conception, Institute of Medicine and National Research Council

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• 1 Front Matter; 2 Summary/Scope of the Study; 3 I. In Vitro Fertilization and Embryo Transfer and Social Concerns; 4 II. Advances in the Practive and Science Base of Medically Assisted Conception; 5 III. Barriers to Progress in In Vitro Fertilization and Embryo Transfer; 6 IV. Research Agenda and Recommendations; 7 Appendix A: Papers Presented at Workshop; 8 Technologies for Assisted Conception/Embryo Transfer in Agricultural and Veterinary Practice; 9 Ovarian Stimulation in Non-Human Primates; 10 Responses to Gonadotropins in Domestic Animals; 11 Membrane Models: Evolution From the Fluid-Mosaic Standby; 12 Mammalian Oocyte Maturation: Mechanisms for Regulation and Prospects for Practical Application of In Vitro Technology; 13 Intragonadal Control of Testis Function; 14 Paracrine Regulation in the Ovary; 15 Experimental Approaches to the Study of Early Developmental Failure in Human Reproduction; 16 The Fertilizing Sperm: Structure, Maturation and Function; 17 Molecular Events Pre- and Post-Fertilization of Mouse Eggs: Oocyte Maturation, Egg Activation, and Polyspermy Block; 18 Glycolytic Pathway in Preimplantation Mammalian Embryos; 19 Regulative Potential of Micromanipulated Embryos; 20 Uterine Receptivity, Maternal Recognition of Pregnancy and Early Embryonic Loss; 21 Towards a Cellular and Molecular Understanding of Implantation in the Human: Implications for Assisted Reproductive Technologies