Bacterial Survival in the Hostile Environment

Dr. Ashutosh Kumar is an active researcher and scientific writer in his field for over 14 years and presently working at Department of Microbiology, Tripura University (A Central University), Suryamaninagar, Agartala, Tripura, India. He received MSc and PhD degree in Biotechnology from University of Hyderabad, India. He did his postdoctoral research at TIFR-National Centre for Biological Sciences Bangalore, Indian Institute of Technology Delhi and Jamia Hamdard, New Delhi, India. He also worked as a Visiting Research Scientist at Robert Koch Institute Berlin, Germany. He has made significant contributions to the study of virulence mechanisms and strategies of survival, adaptation, and persistence of Mycobacterium tuberculosis. He was involved in identification of an enzyme from M. tuberculosis that promote biofilm formation and drugs that enhanced the potency of two current anti-tuberculosis antibiotics. He received many scholarships, awards, and fellowship during his education. He has many publications in international journals and books. Dr. Tenguria is an active researcher and currently working as Project Scientist in Cedars-Sinai Medical Center, Los Angeles, CA USA. He has been actively involved in research and training of graduate and undergraduate students. He received his MSc in Life Sciences from University of Rajasthan, Jaipur and PhD in Biotechnology from University of Hyderabad, Hyderabad, India. He received his postdoctoral training from Purdue University, Indiana, USA and Cedars-Sinai Medical Center (UCLA), Los Angeles, California, USA. Currently, he is working in the area of molecular innate immunity to unravel molecular signaling mechanics for sensing danger (infectious pathogens) signals through cytosolic receptors of the innate immune system of human and mouse hosts. With his doctoral and postdoctoral fellowships and research in the area of host-microbe interactions, bacterial survival and pathogenesis, he made seminal contributions by publishing in international Jr (Cell Host-Microbe, Nature Commun, Frontiers).

• Chapter 1. Mycobacterium tuberculosis adaptation to host environmentChapter 2. Modulation of host pathways by Mycobacterium tuberculosis for survivalChapter 3. Signaling nucleotides in bacteriaChapter 4. The fish immune armaments in response to pathogen invasion—a tour inside the macrophagesChapter 5. Essential proteins for the survival of bacteria in hostile environmentChapter 6. Kinases and phosphatases in bacterial survival in hostile environmentChapter 7. Antimicrobial resistance—a serious global threatChapter 8. Combination of virulence and antibiotic resistance: a successful bacterial strategy to survive under hostile environmentsChapter 9. Mechanisms of biofilm-based antibiotic resistance and tolerance in Mycobacterium tuberculosisChapter 10. Biofilms: cities of microorganismsChapter 11. Biofilm: a coordinated response of bacteria against stressesChapter 12. The bacterial communication system and its interference as an antivirulence strategyChapter 13. Microbial adaptations in extreme environmental conditionsChapter 14. Adaptation strategies of piezophilic microbesChapter 15. Survival and adaptation strategies of microorganisms in the extreme radiationChapter 16. Adaptation strategies of thermophilic microbes