Allergic and Immunologic Diseases

Christopher Chang, MD, PhD, is Chief of Immunology, Allergy and Pediatric Rheumatology at Joe DiMaggio Children's Hospital and Memorial Healthcare System. He holds appointments as Professor of Medicine at the University of California, Davis, Professor of Allergy and Immunology at Nova Southeastern University, and Professor of Pediatrics at Florida Atlantic and Florida International Universities. His research focuses on immunodysregulation, primary immunodeficiencies, autoimmunity, epigenetics, atopic dermatitis, and food allergy, with a special interest in artificial intelligence in medicine. He serves as Medical Director of Pediatric Research at Joe DiMaggio Children's Hospital and is Editor-in-Chief of Clinical Reviews in Allergy and Immunology and the Journal of Evidence-based Integrative Medicine. He is a Fellow of the AAAAI and a Regent of the ACAAI.

"...a comprehensive resource on allergic and immunologic diseases that includes all need-to-know information from basics to clinical practice,… an in-depth reference guide on the fundamental aspects of basic and clinical allergic and immunologic diseases…. [A] few features of this book [are] fascinating. First, the table of contents has detailed subheadings; second, each chapter has a section entitled "how to use this chapter"; and finally, the "clinical pearls" section highlights the important teaching points of each chapter. This book is a valuable resource on allergic and immunologic diseases. It shares the expertise of over 100 contributors in a two-volume collection. Those who care for allergic patients will find this book practical and beneficial on a day-to-day basis." --©Doody’s Review Service, 2023, Massoud Mahmoudi, DO, PhD (University of California San Francisco)

• Section A: Background1. A history of allergy and immunology2. The development of clinical laboratory methods in the diagnosis of human disease3. Discoveries with significant impact in how we diagnosis and treat diseases4. Taking an allergy and immunology history and physical5. Basic genetics and epigenetics for the immunologist and allergist6. Immunological studies – utility and limitations7. Future developments and how they will impact the practice of medicineSection B: Diagnosis of allergic diseases8. Epicutaneous and intradermal skin testing9. The interpretation of epicutaneous and intradermal skin testing for foods10. The use of in vitro methods to evaluate allergy11. Food challenges12. Testing for the physical urticarias13. Techniques to evaluate asthma14. Drug allergy testing15. Sinus diseases and rhinolaryngoscopy16. Approach to the rash from an allergy/immunology perspective17. Patch testing and the evaluation of contact allergy18. Skin biopsies and their utility19. The evaluation of mast cell related disorders20. The evaluation of a patient with urticaria and angioedema21. Evaluating the patient with eosinophilia or eosinophilic disease22. Unproven and controversial testing methods in allergy and immunologySection C: Evaluation of immune function23. Testing for primary immunodeficiency24. Testing the innate immune system25. Testing the adaptive immune system26. Periodic fever syndromes and autoinflammatory diseases27. Immunological dysfunction disorders28. The AIDS workup29. Basic workup for autoimmune diseases30. Neuroimmunology31. Genetic testingSection D: Treatment of allergic and immunologic diseases32. Immunotherapy to environmental allergens33. Drug allergy desensitization methods34. Oral, sublingual and dermatologic immunotherapy to food allergens35. Conventional medications for the treatment of allergic diseases36. The new biologicals in allergy37. Action plans and quality of life evaluations38. The treatment of atopic dermatitis39. The recognition and treatment of anaphylaxis40. Treatment of venom and other insect allergies41. Drugs and treatment modalities for itch and hives42. Integrative medicine in allergy and immunologySection E: Treatment of immunological disorders43. Treatment of the patient with PIDD44. Management of autoinflammatory syndromes and periodic fevers45. Immunomodulatory pharmaceuticals for the treatment of immune dysfunction46. Bone marrow transplant for the patient with monogenic PIDD47. The immunological management of the solid-organ transplant patient48. Apheresis49. Pharmaceuticals for AIDS50. Gene therapy