Geometric Induction of Bone Formation

Ugo Ripamonti is a leader in the field of tissue induction and differentiation in postnatal osteogenesis. His principal achievement is the demonstration of the induction of bone formation in non-human primate models. In 1994 he was appointed professor at the Medical School University of the Witwatersrand, Johannesburg, in South Africa, leading its newly founded Bone Research Laboratory. He has written more than 200 publications, given more than 120 invited lectures at international symposia, and organized a series of workshops and symposia at the World Biomaterials Congresses and the International Conferences on Bone Morphogenetic Proteins.

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• Preface/Introduction The Geometric Induction of Bone Formation Ugo Ripamonti and Hari A Reddi Chapter 1 The New Frontiers in Bone Tissue Engineering: Functionalized Biomimetic Surfaces beyond Morphogens and Stem Cells Ugo Ripamonti and Laura C. RodenChapter 2 The Induction of Bone Formation: When and Why Bone Forms and Sometime Repair and Regenerate: The Enigmatic Myth of Bone Tissue Engineering and the Dream of Regenerative Medicine Ugo Ripamonti Chapter 3 The Induction of Bone Formation and the Osteogenic Proteins of the Transforming Growth Factor-β Supergene Family: Pleiotropism and Redundancy Ugo RipamontiChapter 4 Coral-Derived Hydroxyapatite-Based Macroporous Bioreactors Initiate the Spontaneous Induction of Bone Formation in Heterotopic Extraskeletal Sites: Morphological Time Studies Ugo RipamontiChapter 5 Concavities of Crystalline Sintered Hydroxyapatite-Based Macroporous Bioreactors Initiate the Spontaneous Induction of Bone Formation Ugo RipamontiChapter 6 Molecular Pathways Regulating the Geometric Induction of Bone Formation: Synthetizing and Embedding Osteogenic Proteins into Nanotopographic Geometries Raquel Duarte and Ugo RipamontiChapter 7 The Spontaneous Induction of Bone Formation by Intrinsically Osteoinductive Bioreactors for Human Patients: Osteoinductive Hydroxyapatite-Coated Titanium Implants Ugo Ripamonti