Tom Strachan is Emeritus Professor of Human Molecular Genetics at Newcastle University, UK. Together with a former colleague, Andrew Read, he writes the popular Human Molecular Genetics textbook, now in its Fifth Edition.Anneke Lucassen is Professor of Genomic Medicine and Director of the Centre for Personalised Medicine at the University of Oxford, UK

This excellent book is a must-have for any library, or anyone deeply interested in genetics and genomics in medicine. The writing is detailed yet easily understandable, and readers will come away much more knowledgeable on thesubject. This second edition is a much needed and exceptionally well-executed update to the original version.- Mark F. Sanders, PhD, UC Davis College of Biological Sciences

• 1. Fundamentals of DNA, Chromosomes, and Cells 2. Fundamentals of Gene Structure, Gene Expression, and Human Genome Organization 3. Principles Underlying Core DNA Technologies 4. Principles of Genetic Variation 5. Single-gene Disorders: Inheritance Patterns, Phenotype Variability, and Allele Frequencies 6. Principles of Gene Regulation and Epigenetics 7. How Genetic Variation in DNA and Chromosomes Causes Disease8. Identifying Disease Genes and Genetic Susceptibility to Complex Disease9. Genetic Approaches to Treating Disease 10. Cancer Genetics and Genomics11. Genetic and Genomic Testing in Healthcare: Practical and Ethical Aspects

Tom Strachan is Emeritus Professor of Human Molecular Genetics at Newcastle University, UK. Together with a former colleague, Andrew Read, he writes the popular Human Molecular Genetics textbook, now in its Fifth Edition.Anneke Lucassen is Professor of Genomic Medicine and Director of the Centre for Personalised Medicine at the University of Oxford, UK

This excellent book is a must-have for any library, or anyone deeply interested in genetics and genomics in medicine. The writing is detailed yet easily understandable, and readers will come away much more knowledgeable on thesubject. This second edition is a much needed and exceptionally well-executed update to the original version.- Mark F. Sanders, PhD, UC Davis College of Biological Sciences

• 1. Fundamentals of DNA, Chromosomes, and Cells 2. Fundamentals of Gene Structure, Gene Expression, and Human Genome Organization 3. Principles Underlying Core DNA Technologies 4. Principles of Genetic Variation 5. Single-gene Disorders: Inheritance Patterns, Phenotype Variability, and Allele Frequencies 6. Principles of Gene Regulation and Epigenetics 7. How Genetic Variation in DNA and Chromosomes Causes Disease8. Identifying Disease Genes and Genetic Susceptibility to Complex Disease9. Genetic Approaches to Treating Disease 10. Cancer Genetics and Genomics11. Genetic and Genomic Testing in Healthcare: Practical and Ethical Aspects

Tom Strachan is Emeritus Professor of Human Molecular Genetics at Newcastle University, UK. Together with a former colleague, Andrew Read, he writes the popular Human Molecular Genetics textbook, now in its Fifth Edition.Anneke Lucassen is Professor of Genomic Medicine and Director of the Centre for Personalised Medicine at the University of Oxford, UK

This excellent book is a must-have for any library, or anyone deeply interested in genetics and genomics in medicine. The writing is detailed yet easily understandable, and readers will come away much more knowledgeable on thesubject. This second edition is a much needed and exceptionally well-executed update to the original version.- Mark F. Sanders, PhD, UC Davis College of Biological Sciences

• 1. Fundamentals of DNA, Chromosomes, and Cells 2. Fundamentals of Gene Structure, Gene Expression, and Human Genome Organization 3. Principles Underlying Core DNA Technologies 4. Principles of Genetic Variation 5. Single-gene Disorders: Inheritance Patterns, Phenotype Variability, and Allele Frequencies 6. Principles of Gene Regulation and Epigenetics 7. How Genetic Variation in DNA and Chromosomes Causes Disease8. Identifying Disease Genes and Genetic Susceptibility to Complex Disease9. Genetic Approaches to Treating Disease 10. Cancer Genetics and Genomics11. Genetic and Genomic Testing in Healthcare: Practical and Ethical Aspects