Jason Sheehan, MD, PhD, FACS, FAANS, is the Vice Chair and Harrison Distinguished Professor of Neurological Surgery at the University of Virginia (UVA). He also serves as the Neurosciences Service Line Director at UVA. Dr. Sheehan is the current chair of the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) Section on Tumors. He is serves as the Editor-In-Chief of the Journal of Neuro-Oncology.Dr. Sheehan has published more than 500 peer-reviewed publications and two-dozen chapters or books. He has received numerous awards including the Leksell Radiosurgery Award, the Integra Foundation Award, the Synthes Skull Base Award, the Robert Florin Award for Neurosurgery Socioeconomics, the AANS American Brain Tumor Foundation Young Investigator Award, the AANS/CNS Tumor Section Basic Science Research Gold Medal, and the Crutchfield Gage Research Award. He has interests in image guided neurosurgical procedures including stereotactic radiosurgery and MR guided focused ultrasound for the management of complex intracranial pathologies such as brain tumors and arteriovenous malformations.L. Dade Lunsford, MD serves as the Lars Leksell Professor and Distinguished Professor at the Department of Neurological Surgery at the University of Pittsburgh. He is also director of the Center for Image-Guided Neurosurgery at the University of Pittsburgh Medical Center and an internationally recognized authority on stereotactic surgery, radiosurgery, and minimally invasive surgery. He has authored or coauthored more than 1000 scientific reports and 16 books.

• Chapter 1 A Short History of Gamma Knife RadiosurgeryJeremy GanzChapter 2 History of LINAC and Proton RadiosurgeryHenry Ruiz-Garcia, Steve Herchko, Jason P. Sheehan, and Daniel M. TrifilettiChapter 3 The History of CyberKnifeMaleeha Ahmad, Antonio Meola, and Steven D. ChangChapter 4 Radiobiology of Stereotactic RadiosurgeryIbrahim Abu-Gheida, Ehsan H. Balagamwala, Samuel T. Chao, and John H. SuhChapter 5 Radiology Considerations for RadiosurgeryPrem Batchala, David Joyner, and Joseph DonahueChapter 6 Physics of Stereotactic RadiosurgeryDavid Schlesinger, Brian Wang, and Stanley BenedictChapter 7 Critical Structures and Tolerances for Intracranial Stereotactic RadiosurgeryPhillip Wall, Matthew S. Susko, Steve E. Braunstein, and Lijun MaChapter 8 Radiosurgery Pathological FundamentalsGyörgy T. Szeifert and L. Dade LunsfordChapter 9 Stereotactic Radiosurgery for Arteriovenous MalformationsL. Dade Lunsford, Andrew Faramand, Hideyuki Kano, and Ajay NiranjanChapter 10 SRS of CavernomasGábor Nagy and Andras A. KemenyChapter 11 Stereotactic Radiosurgery for Dural Arteriovenous FistulasCheng-Chia Lee, Huai-Che Yang, Yong-Sin Hu, Chung-Jung Lin, Hsiu-Mei Wu, Wan-Yuo Guo, Wen-Yuh Chung, and David HC PanChapter 12 Stereotactic Radiosurgery for MeningiomasSonia Ajmera, Andrew I. Yang, and John Y. K. LeeChapter 13 Solitary Fibrous Tumor (Hemangiopericytoma)Johnnie Hodge, David E. Arsanious, Stylianos Pikis, and Christopher P. CifarelliChapter 14 SRS for Nonfunctioning Pituitary AdenomasTafadzwa L. Chaunzwa, Marc R. Bussière, Jay S. Loeffler, and Helen A. ShihChapter 15 Stereotactic Radiosurgery for Functioning Pituitary AdenomasAdomas Bunevicius and Jason SheehanChapter 16 Stereotactic Radiosurgery for CraniopharyngiomasStylianos Pikis, Adomas Bunevicius, and Jason SheehanChapter 17 SRS for Chordomas and ChondrosarcomasGhusn Al Sideiri, Farid El Hefnawi, and Gene BarnettChapter 18 Stereotactic Radiosurgery for Glomus TumorsManjul Tripathi, Harsh Deora, Nishanth Sadashiva, Chirag K Ahuja, and Narendra KumarChapter 19 Stereotactic Radiosurgery for HemangioblastomasAjay Niranjan and L. Dade LunsfordChapter 20 Stereotactic Radiosurgery for Vestibular SchwannomaHirotaka Hasegawa, Bruce E. Pollock, and Michael J. LinkChapter 21 SRS for Vestibular Schwannomas in Neurofibromatosis Type 2Shibin SunChapter 22 Stereotactic Radiosurgery for Nonvestibular SchwannomasAnne-Marie Langlois and David MathieuChapter 23 Stereotactic Radiosurgery for Facial NeuralgiasAndrew Ajisebutu and Anthony M. KaufmannChapter 24 Radiosurgery for Movement DisordersTony R. Wang, Srinivas Chivukula, and Nader PouratianChapter 25 SRS for OCDRoberto Martínez-Álvarez, Nuria Martínez-Moreno, Cristina Torres-Díaz, and Mónica Lara-AlmuniaChapter 26 Stereotactic Radiosurgery for Hypothalamic HamartomasPantaleo Romanelli and Alfredo ContiChapter 27 Radiosurgical Modulation for EpilepsyJean Régis and Hussein HamdiChapter 28 Radiosurgery for Ocular DisordersRoman Liscak and Gabriela SimonovaChapter 29 Stereotactic Radiosurgery for Pediatric Brain Tumors and Arteriovenous MalformationsYavuz Samanci and Selcuk PekerChapter 30 Stereotactic Radiosurgery and Hypofractionated Stereotactic Radiotherapy for GliomasJoseph Tsai and Simon S LoChapter 31 Stereotactic Radiosurgery for the Management of One to Five Brain MetastasesApril Vassantachart, Jason C. Ye, Gabriel Zada, and Eric L. ChangChapter 32 Stereotactic Radiosurgery for ≥5 Brain MetastasesBernadine Donahue, Jason Gurewitz, Carolina Benjamin, Kenneth Bernstein Joshua Silverman,Erik Sulman, and Douglas KondziolkaChapter 33 Hypofractionated Stereotactic Radiosurgery for Brain MetastasesMichael H. Wang, Sten Myrehaug, Hany Soliman, Chia-Lin Tseng, Jay Detsky, Zain Husain, Mary Jane Lim-Fat, Sunit Das, Nir Lipsman, Simon S. Lo, Lijun Ma, Mark Ruschin, and Arjun SahgalChapter 34 Stereotactic Radiosurgery and ImmunotherapyRupesh Kotecha, Raees Tonse, Camilo E. Fadul, and Manmeet S. AhluwaliaChapter 35 Repeat Stereotactic Radiosurgery for Brain MetastasisAhmed Halima, John H. Suh, Simon S. Lo, Lilyana Angelov, Erin S. Murphy, and Samuel T. ChaoChapter 36 Recognition and Management of Adverse Radiation EffectsStephanie Cheok, James E. Hansen, and Veronica L. Chiang

Jason Sheehan, MD, PhD, FACS, FAANS, is the Vice Chair and Harrison Distinguished Professor of Neurological Surgery at the University of Virginia (UVA). He also serves as the Neurosciences Service Line Director at UVA. Dr. Sheehan is the current chair of the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) Section on Tumors. He is serves as the Editor-In-Chief of the Journal of Neuro-Oncology.Dr. Sheehan has published more than 500 peer-reviewed publications and two-dozen chapters or books. He has received numerous awards including the Leksell Radiosurgery Award, the Integra Foundation Award, the Synthes Skull Base Award, the Robert Florin Award for Neurosurgery Socioeconomics, the AANS American Brain Tumor Foundation Young Investigator Award, the AANS/CNS Tumor Section Basic Science Research Gold Medal, and the Crutchfield Gage Research Award. He has interests in image guided neurosurgical procedures including stereotactic radiosurgery and MR guided focused ultrasound for the management of complex intracranial pathologies such as brain tumors and arteriovenous malformations.L. Dade Lunsford, MD serves as the Lars Leksell Professor and Distinguished Professor at the Department of Neurological Surgery at the University of Pittsburgh. He is also director of the Center for Image-Guided Neurosurgery at the University of Pittsburgh Medical Center and an internationally recognized authority on stereotactic surgery, radiosurgery, and minimally invasive surgery. He has authored or coauthored more than 1000 scientific reports and 16 books.

• Chapter 1 A Short History of Gamma Knife RadiosurgeryJeremy GanzChapter 2 History of LINAC and Proton RadiosurgeryHenry Ruiz-Garcia, Steve Herchko, Jason P. Sheehan, and Daniel M. TrifilettiChapter 3 The History of CyberKnifeMaleeha Ahmad, Antonio Meola, and Steven D. ChangChapter 4 Radiobiology of Stereotactic RadiosurgeryIbrahim Abu-Gheida, Ehsan H. Balagamwala, Samuel T. Chao, and John H. SuhChapter 5 Radiology Considerations for RadiosurgeryPrem Batchala, David Joyner, and Joseph DonahueChapter 6 Physics of Stereotactic RadiosurgeryDavid Schlesinger, Brian Wang, and Stanley BenedictChapter 7 Critical Structures and Tolerances for Intracranial Stereotactic RadiosurgeryPhillip Wall, Matthew S. Susko, Steve E. Braunstein, and Lijun MaChapter 8 Radiosurgery Pathological FundamentalsGyörgy T. Szeifert and L. Dade LunsfordChapter 9 Stereotactic Radiosurgery for Arteriovenous MalformationsL. Dade Lunsford, Andrew Faramand, Hideyuki Kano, and Ajay NiranjanChapter 10 SRS of CavernomasGábor Nagy and Andras A. KemenyChapter 11 Stereotactic Radiosurgery for Dural Arteriovenous FistulasCheng-Chia Lee, Huai-Che Yang, Yong-Sin Hu, Chung-Jung Lin, Hsiu-Mei Wu, Wan-Yuo Guo, Wen-Yuh Chung, and David HC PanChapter 12 Stereotactic Radiosurgery for MeningiomasSonia Ajmera, Andrew I. Yang, and John Y. K. LeeChapter 13 Solitary Fibrous Tumor (Hemangiopericytoma)Johnnie Hodge, David E. Arsanious, Stylianos Pikis, and Christopher P. CifarelliChapter 14 SRS for Nonfunctioning Pituitary AdenomasTafadzwa L. Chaunzwa, Marc R. Bussière, Jay S. Loeffler, and Helen A. ShihChapter 15 Stereotactic Radiosurgery for Functioning Pituitary AdenomasAdomas Bunevicius and Jason SheehanChapter 16 Stereotactic Radiosurgery for CraniopharyngiomasStylianos Pikis, Adomas Bunevicius, and Jason SheehanChapter 17 SRS for Chordomas and ChondrosarcomasGhusn Al Sideiri, Farid El Hefnawi, and Gene BarnettChapter 18 Stereotactic Radiosurgery for Glomus TumorsManjul Tripathi, Harsh Deora, Nishanth Sadashiva, Chirag K Ahuja, and Narendra KumarChapter 19 Stereotactic Radiosurgery for HemangioblastomasAjay Niranjan and L. Dade LunsfordChapter 20 Stereotactic Radiosurgery for Vestibular SchwannomaHirotaka Hasegawa, Bruce E. Pollock, and Michael J. LinkChapter 21 SRS for Vestibular Schwannomas in Neurofibromatosis Type 2Shibin SunChapter 22 Stereotactic Radiosurgery for Nonvestibular SchwannomasAnne-Marie Langlois and David MathieuChapter 23 Stereotactic Radiosurgery for Facial NeuralgiasAndrew Ajisebutu and Anthony M. KaufmannChapter 24 Radiosurgery for Movement DisordersTony R. Wang, Srinivas Chivukula, and Nader PouratianChapter 25 SRS for OCDRoberto Martínez-Álvarez, Nuria Martínez-Moreno, Cristina Torres-Díaz, and Mónica Lara-AlmuniaChapter 26 Stereotactic Radiosurgery for Hypothalamic HamartomasPantaleo Romanelli and Alfredo ContiChapter 27 Radiosurgical Modulation for EpilepsyJean Régis and Hussein HamdiChapter 28 Radiosurgery for Ocular DisordersRoman Liscak and Gabriela SimonovaChapter 29 Stereotactic Radiosurgery for Pediatric Brain Tumors and Arteriovenous MalformationsYavuz Samanci and Selcuk PekerChapter 30 Stereotactic Radiosurgery and Hypofractionated Stereotactic Radiotherapy for GliomasJoseph Tsai and Simon S LoChapter 31 Stereotactic Radiosurgery for the Management of One to Five Brain MetastasesApril Vassantachart, Jason C. Ye, Gabriel Zada, and Eric L. ChangChapter 32 Stereotactic Radiosurgery for ≥5 Brain MetastasesBernadine Donahue, Jason Gurewitz, Carolina Benjamin, Kenneth Bernstein Joshua Silverman,Erik Sulman, and Douglas KondziolkaChapter 33 Hypofractionated Stereotactic Radiosurgery for Brain MetastasesMichael H. Wang, Sten Myrehaug, Hany Soliman, Chia-Lin Tseng, Jay Detsky, Zain Husain, Mary Jane Lim-Fat, Sunit Das, Nir Lipsman, Simon S. Lo, Lijun Ma, Mark Ruschin, and Arjun SahgalChapter 34 Stereotactic Radiosurgery and ImmunotherapyRupesh Kotecha, Raees Tonse, Camilo E. Fadul, and Manmeet S. AhluwaliaChapter 35 Repeat Stereotactic Radiosurgery for Brain MetastasisAhmed Halima, John H. Suh, Simon S. Lo, Lilyana Angelov, Erin S. Murphy, and Samuel T. ChaoChapter 36 Recognition and Management of Adverse Radiation EffectsStephanie Cheok, James E. Hansen, and Veronica L. Chiang

Jason Sheehan, MD, PhD, FACS, FAANS, is the Vice Chair and Harrison Distinguished Professor of Neurological Surgery at the University of Virginia (UVA). He also serves as the Neurosciences Service Line Director at UVA. Dr. Sheehan is the current chair of the American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) Section on Tumors. He is serves as the Editor-In-Chief of the Journal of Neuro-Oncology.Dr. Sheehan has published more than 500 peer-reviewed publications and two-dozen chapters or books. He has received numerous awards including the Leksell Radiosurgery Award, the Integra Foundation Award, the Synthes Skull Base Award, the Robert Florin Award for Neurosurgery Socioeconomics, the AANS American Brain Tumor Foundation Young Investigator Award, the AANS/CNS Tumor Section Basic Science Research Gold Medal, and the Crutchfield Gage Research Award. He has interests in image guided neurosurgical procedures including stereotactic radiosurgery and MR guided focused ultrasound for the management of complex intracranial pathologies such as brain tumors and arteriovenous malformations.L. Dade Lunsford, MD serves as the Lars Leksell Professor and Distinguished Professor at the Department of Neurological Surgery at the University of Pittsburgh. He is also director of the Center for Image-Guided Neurosurgery at the University of Pittsburgh Medical Center and an internationally recognized authority on stereotactic surgery, radiosurgery, and minimally invasive surgery. He has authored or coauthored more than 1000 scientific reports and 16 books.

• Chapter 1 A Short History of Gamma Knife RadiosurgeryJeremy GanzChapter 2 History of LINAC and Proton RadiosurgeryHenry Ruiz-Garcia, Steve Herchko, Jason P. Sheehan, and Daniel M. TrifilettiChapter 3 The History of CyberKnifeMaleeha Ahmad, Antonio Meola, and Steven D. ChangChapter 4 Radiobiology of Stereotactic RadiosurgeryIbrahim Abu-Gheida, Ehsan H. Balagamwala, Samuel T. Chao, and John H. SuhChapter 5 Radiology Considerations for RadiosurgeryPrem Batchala, David Joyner, and Joseph DonahueChapter 6 Physics of Stereotactic RadiosurgeryDavid Schlesinger, Brian Wang, and Stanley BenedictChapter 7 Critical Structures and Tolerances for Intracranial Stereotactic RadiosurgeryPhillip Wall, Matthew S. Susko, Steve E. Braunstein, and Lijun MaChapter 8 Radiosurgery Pathological FundamentalsGyörgy T. Szeifert and L. Dade LunsfordChapter 9 Stereotactic Radiosurgery for Arteriovenous MalformationsL. Dade Lunsford, Andrew Faramand, Hideyuki Kano, and Ajay NiranjanChapter 10 SRS of CavernomasGábor Nagy and Andras A. KemenyChapter 11 Stereotactic Radiosurgery for Dural Arteriovenous FistulasCheng-Chia Lee, Huai-Che Yang, Yong-Sin Hu, Chung-Jung Lin, Hsiu-Mei Wu, Wan-Yuo Guo, Wen-Yuh Chung, and David HC PanChapter 12 Stereotactic Radiosurgery for MeningiomasSonia Ajmera, Andrew I. Yang, and John Y. K. LeeChapter 13 Solitary Fibrous Tumor (Hemangiopericytoma)Johnnie Hodge, David E. Arsanious, Stylianos Pikis, and Christopher P. CifarelliChapter 14 SRS for Nonfunctioning Pituitary AdenomasTafadzwa L. Chaunzwa, Marc R. Bussière, Jay S. Loeffler, and Helen A. ShihChapter 15 Stereotactic Radiosurgery for Functioning Pituitary AdenomasAdomas Bunevicius and Jason SheehanChapter 16 Stereotactic Radiosurgery for CraniopharyngiomasStylianos Pikis, Adomas Bunevicius, and Jason SheehanChapter 17 SRS for Chordomas and ChondrosarcomasGhusn Al Sideiri, Farid El Hefnawi, and Gene BarnettChapter 18 Stereotactic Radiosurgery for Glomus TumorsManjul Tripathi, Harsh Deora, Nishanth Sadashiva, Chirag K Ahuja, and Narendra KumarChapter 19 Stereotactic Radiosurgery for HemangioblastomasAjay Niranjan and L. Dade LunsfordChapter 20 Stereotactic Radiosurgery for Vestibular SchwannomaHirotaka Hasegawa, Bruce E. Pollock, and Michael J. LinkChapter 21 SRS for Vestibular Schwannomas in Neurofibromatosis Type 2Shibin SunChapter 22 Stereotactic Radiosurgery for Nonvestibular SchwannomasAnne-Marie Langlois and David MathieuChapter 23 Stereotactic Radiosurgery for Facial NeuralgiasAndrew Ajisebutu and Anthony M. KaufmannChapter 24 Radiosurgery for Movement DisordersTony R. Wang, Srinivas Chivukula, and Nader PouratianChapter 25 SRS for OCDRoberto Martínez-Álvarez, Nuria Martínez-Moreno, Cristina Torres-Díaz, and Mónica Lara-AlmuniaChapter 26 Stereotactic Radiosurgery for Hypothalamic HamartomasPantaleo Romanelli and Alfredo ContiChapter 27 Radiosurgical Modulation for EpilepsyJean Régis and Hussein HamdiChapter 28 Radiosurgery for Ocular DisordersRoman Liscak and Gabriela SimonovaChapter 29 Stereotactic Radiosurgery for Pediatric Brain Tumors and Arteriovenous MalformationsYavuz Samanci and Selcuk PekerChapter 30 Stereotactic Radiosurgery and Hypofractionated Stereotactic Radiotherapy for GliomasJoseph Tsai and Simon S LoChapter 31 Stereotactic Radiosurgery for the Management of One to Five Brain MetastasesApril Vassantachart, Jason C. Ye, Gabriel Zada, and Eric L. ChangChapter 32 Stereotactic Radiosurgery for ≥5 Brain MetastasesBernadine Donahue, Jason Gurewitz, Carolina Benjamin, Kenneth Bernstein Joshua Silverman,Erik Sulman, and Douglas KondziolkaChapter 33 Hypofractionated Stereotactic Radiosurgery for Brain MetastasesMichael H. Wang, Sten Myrehaug, Hany Soliman, Chia-Lin Tseng, Jay Detsky, Zain Husain, Mary Jane Lim-Fat, Sunit Das, Nir Lipsman, Simon S. Lo, Lijun Ma, Mark Ruschin, and Arjun SahgalChapter 34 Stereotactic Radiosurgery and ImmunotherapyRupesh Kotecha, Raees Tonse, Camilo E. Fadul, and Manmeet S. AhluwaliaChapter 35 Repeat Stereotactic Radiosurgery for Brain MetastasisAhmed Halima, John H. Suh, Simon S. Lo, Lilyana Angelov, Erin S. Murphy, and Samuel T. ChaoChapter 36 Recognition and Management of Adverse Radiation EffectsStephanie Cheok, James E. Hansen, and Veronica L. Chiang