Clinical Applications of Magnetic Nanoparticles

Professor Nguyen TK Thanh, FRSC, MInstP (http://www.ntk-thanh.co.uk) held a prestigious Royal Society University Research Fellowship (2005-2014). She was appointed a Full Professor in Nanomaterials in 2013 at Biophysics Group, Department of Physics and Astronomy, University College London, UK. She leads a very dynamic group conducting cutting edge interdisciplinary and innovative research on the design, and synthesis of magnetic and plasmonic nanomaterials for biomedical applications. A very strong feature of her research program is the development of new chemical methods and in collaboration with chemical engineers to produce the next generation of nanoparticles with very high magnetic moment, and novel hybrid and multifunctional nanostructures. Detailed mechanistic studies of their formation by sophisticated and advanced analysis of the nanostructure allows tuning of the physical properties at the nanoscale; these can subsequently be exploited for diagnosis and treatment of various diseases. The studies are conducted to provide insight for future material design approaches. It will also help to identify the critical process parameters that can be manipulated in order to obtain the suitable physical properties for the intended applications. She was the sole editor of the book: "MAGNETIC NANOPARTICLES: FROM FABRICATION TO CLINICAL APPLICATIONS" published by CRC Press/Taylor and Francis: http://www.crcpress.com/product/isbn/9781439869321. In 2016, she was a Guest Editor of The Royal Society Interface Focus on "Multifunctional nanostructures for diagnosis and therapy of diseases". She has published over 80 peer reviewed journal articles and book chapters with over 4000 citations so far. She has been Visiting Professors at various Universities in France, Japan, China and Singapore. She has been an invited speaker at nearly 200 institutes and scientific meetings. She has a leadership role in professional communities by chairing and organising 30 high profile international conferences such as American Chemistry Society symposia in 2018, 2012, 2010; Royal Society of Chemistry UK Colloids Conferences in 2017, 2014, 2011; European Material Research Society Symposia in 2016, 2013; ICMAT Singapore in 2015, 2013; Faraday Discussions in 2014 and being a member of advisory boards in Europe, USA and Japan. She served in Joint Committee of the Royal Society of Chemistry Colloid & Interface Science Group and the Society of Chemical Industry Colloid & Surface Chemistry Group (2008-2017). She is an elected member of The Royal Society of Chemistry Faraday Division Council and currently serving in Awards Committee and was a representative member of Joint Colloids Groups (2013-2016). She is a workgroup leader of EU COST Action TD1402 on Multifunctional Nanoparticles for Magnetic Hyperthermia and Indirect Radiation Therapy (RADIOMAG). She is a Co-chair of the 13th International Conference on the Scientific and Clinical Applications of Magnetic Carriers in June 2020, London, UK.

• Fabrication and Characterisation of MNPsControlling the size and the shape of uniform magnetic iron oxide nanoparticles for biomedical applicationsMagnetic Nanochains: properties, synthesis and prospectsMagnetisation dynamics for magnetic particle detection at the nano-scaleBiofunctionalisation of MNPs for Biomedical ApplicationChallenge of functionalisation of MNPsIron oxide nanoparticles embedded in polymer vesicles as contrast agent for MRIEncapsulation of drugs in functionalized nanoparticles MNPsEx-vivo Application of MNPsWorking Principles of Magnetic Separation for Biomedical Diagnostic ApplicationsMagnetic separation in integrated micro analytical systemsMagnetic-Plasmonic Hybrid Nanoparticles for Organelle SeparationMagnetic nanoparticles based biosensing. Metallic nanoparticles (carbon coated)In-vivo Application of MNPsImmunotoxicity and safety considerations for iron oxide nanoparticlesImpact of core and functionalized magnetic nanoparticles on human healthMechanisms of macrophage recognition of iron oxide nanoparticlesBioheat modelingDesigning Magnetic Nanoparticles for Cancer Treatment using Magnetic HyperthermiaNanoparticles for nanorobotic agents dedicated to cancer therapySmart nanoparticles an the effects in magnetic hyperthermia in vivoNon-invasive guidance scheme of magnetic nanoparticles for drug targeting in Alzheimer’s diseaseDevelopment of magnetic porous PDMS for on-demand drug delivery applicationsFerrofluid for hyperthermia and targeted and sustained drug deliveryMagnetic Particle Transport through Complex MediaMagnetic nanoparticles for neural engineeringMRIMultimodal imaging of magnetic nanoparticles: applications and methodologiesRed Blood Cell constructs to prolong in vivo the life span of iron-based MRI/MPI contrasting agentsAnimal Studies of Magnetic NanoparticlesBio-inspired magnetic nanoparticles for biomedical applicationsMicrowheel for blood clotStimuli regulated Cancer Theranostics Based on Magnetic NanoparticlesRegulatory and CommercialisationGood Manufacturing Practices (GMP) of Magnetic nanoparticlesCommericalisation of new variety of magnetic particles to the global market