Basic Physiology of the Growth Hormone/Insulin-Like Growth Factor Axis.- Experimental Models for Understanding the Role of Insulin-like Growth Factor-I and Its Receptor During Development.- Insulin-like Growth Factor Binding Proteins in Development.- Growth Hormone, Insulin-like Growth Factors and the Female Reproductive System.- Skeletal Muscle.- Cardiovascular and Respiratory Systems.- Hematopoiesis.- Brain Development.- Regulation of Vertebrate Sensory Organ Development: A Scenario for Growth Hormone and Insulin-Like Growth Factors Action.- Role of Insulin-Like Growth Factors in Neuronal Plasticity and Neuroprotection.- Aging and Life Span.- Interactions of Insulin-Like Growth Factor-I and Estrogen in the Brain.- Cancer.- Genetic Basis of Proportional Short Stature.- Future Perspectives.