Kidney Transplantation

Stuart Knechtle, M.D. is the William R. Kenan, Jr. Professor of Surgery and Executive Director of the Duke Transplant Center. He trained in surgery at Duke and in transplant surgery at the University of Wisconsin, Madison where he was appointed as the first Ray D. Owen Professor of Transplantation. He moved to Emory University in 2008 as the Carlos and Marguerite Mason Professor of Liver Transplantation. In 2015 he returned to Duke to establish the Duke Transplant Center and serve as its Executive Director. He holds the William R. Kenan, Jr. Chair in Surgery at Duke. His clinical practice includes kidney, pancreas, and liver transplantation. He directs translational research in transplant immunology and currently serves as Principal Investigator of two NIH-funded clinical trials addressing the challenges of antibody-mediated injury of kidney transplants. He has published over 400 peer reviewed papers, over 60 book chapters, edited four textbooks, and serves on several editorial boards including Annals of Surgery. Lorna Marson is Professor of Transplant Surgery at the University of Edinburgh, and Honorary Consultant Surgeon at the Royal Infirmary of Edinburgh. Lorna held a Clinician Scientist Award from the Academy of Medical Sciences/ Health Foundation from 2003-2008, and continues to work in clinically relevant research in renal transplantation, with translation of a novel agent from bench to bedside. Lorna is Past President of the British Transplantation Society, elected Board member of the European Kidney Transplant Association, and Co-Director of the UK Organ Donation and Transplantation Research Network. She is Associate Medical Director for Research and Development, Organ and Tissues Donation and Transplantation, NHS Blood and Transplant.

"...covers a broad range of topics relevant to kidney transplantation in a single, hardcover volume that includes 43 chapters and is just over 800 pages....this series has intended to serve as a comprehensive guide to the field of kidney transplantation. This book continues to fulfill that goal, with comprehensive discussions of all the basic aspects of transplant medicine..... offers a general overview of a broad range of topics and will be useful to anyone caring for transplant patients, especially those without dedicated training in the field such as students, hospitalists, primary care providers, or general nephrologists and surgeons. The broad nature of the topics covered means sacrificing some in-depth discussions, making this more suited for general practitioners than transplant nephrologists or surgeons. The chapters included here are uniformly well-written and include an abundance of useful references and illustrations.... Overall, the flow of chapters within the textbook is logical, and there are no obvious topics overlooked - an excellent, essential resource." Review by Sam Beavin, MD (University of Kentucky College of Medicine), ©Doody's Review Service 2025. Doody's Score: 88, 3 Stars

• 1. Kidney Transplantation: A History2. The Immunology of Transplantation3. Chronic Kidney Failure: Renal Replacement Therapy4. The Recipient of a Renal Transplant5. Access for Renal Replacement Therapy6. Brain Death and Cardiac Death: Donor Criteria and Care of Deceased Donor7. Medical Evaluation of the Living Donor8. Donor Nephrectomy9. Kidney Preservation10. Histocompatability in Kidney Transplantation11. Surgical Techniques of Kidney Transplantation12. Urological Complications After Kidney Transplant and Transplantation Into an Abnormal Bladder13. Perioperative Care of Patients Undergoing Kidney Transplantation14. Early Course of the Patient With a Kidney Transplant15. Azathioprine and Mycophenolates16. Steroids17. Calcineurin Inhibitors18. mTOR Inhibitors: Sirolimus and Everolimus19. Antilymphocyte Globulin, Monoclonal Antibodies, and Fusion Proteins20. Other Forms of Immunosuppression21. Approaches to the Induction of Tolerance22. Transplantation in the Sensitized Recipient and Across ABO Blood Groups23. Paired Exchange Programs for Living Donors,24. Kidney Allocation25. Pathology of Kidney Transplantation26. Biomarkers for Posttransplant Allograft Monitoring27. Chronic Allograft Failure28. Vascular and Lymphatic Complications After Kidney Transplantation29. Cardiovascular Disease in Renal Transplantation30. Infection in Kidney Transplant Recipients31. Transplantation in a Pandemic: Lessons Learned From COVID-1932. Liver Disease Among Renal Transplant Recipients33. Neurological Complications After Kidney Transplantation34. Cutaneous Disease in Kidney Transplantation Patients35. Cancer in Kidney Failure and Kidney Transplantation36. Pancreas and Kidney Transplantation for Diabetic Nephropathy37. Kidney Transplantation in Children38. Advancing Kidney Transplantation in Low- and Middle-Income Countries: Challenges and Strategies39. Results of Kidney Transplantation40. Psychosocial Aspects of Kidney Transplantation and Living Kidney Donation41. Ethical and Legal Aspects of Kidney Donation42. Xenotransplantation43. Evidence in Transplantation