David Randall is Honorary Clinical Senior Lecturer, Barts and the London School of Medicine and Dentistry, QMUL; Consultant Physician and Nephrologist, Barts Health NHS Trust, London, UK. John Booth, Honorary Clinical Senior Lecturer, Barts and the London School of Medicine and Dentistry, QMUL; Consultant Physician and Nephrologist, Barts Health NHS Trust, London, United Kingdom Kate Wiles, Honorary Senior Lecturer, Wolfson Institute of Population Health, Queen Mary University of London; Consultant Obstetric Physician, Department of Women's Health, Barts Health NHS Trust, London, UK.

"I suspect this book is equally well known to both undergraduate and postgraduate medics. It was first published in 1987, so I suspect it has been widely used in medical schools as well as by doctors looking to refresh or use it for exams. It also transcends and offers support to primary and secondary care practitioners, and few medical textbooks can claim to cover all these demographic groups.... This book seems to cover an amazing number of topics in significant depth, and all the main specialties are covered as well as young adults and the elderly plus obstetric medicine.... As in keeping with modern textbooks, there is a top-class layout with illustrative figures and boxes and an excellent use of colour and plenty of text that is easy to read.... [it] is quite frankly fantastic, a modern review of clinical medicine with excellent, wide-ranging coverage, and it will appeal to a wide audience, from medical students to established healthcare professionals." Review by Dr Harry Brown, Geriatric Medicine Journal (Pavilion Health Today), January 2026User reviews, Amazon UK:“So in depth yet concise and organised. Perfect for a medical student. Really helped revise for my pre med exams and also do my coursework. Great value for money. Really great structure and layout. Made the content far more readable than what was supplied in lectures.”“Great textbook and if you only have the money to buy one I’d recommend this one.”“Best book for anyone from the Medical Profession. Wish I had found it earlier….”

• PART 1 THE PRACTICE OF MEDICINE1. The art of being a doctor2. Clinical communication3. Medical ethics4. Evidence-based practice5. Human genetics6. Immunity7. Therapeutics and prescribing8. RadiologyPART 2 MEDICINE AND THE WORLD9. Public health10. Global and planetary healthPART 3 ACUTE AND EMERGENCY MEDICINE11. Acute medicine12. Sepsis and the treatment of bacterial infection13. Critical care medicine14. Anaesthesia and perioperative medicine15. Toxicology16. Environmental medicinePART 4 MEDICAL SPECIALTIES17. Cardiology18. Hypertension19. Lipid and metabolic disorders20. Respiratory medicine21. Ear, nose, and throat22. Gastroenterology23. Hepatology24. Biliary tract and pancreatic disease25. Nutrition26. Kidney and urinary tract disease27. Water balance, fluids, and electrolytes28. Neurology29. Stroke medicine30. General hospital psychiatry31. Ophthalmology32. Rheumatology33. Bone disease34. Endocrinology35. Diabetes mellitus36. Metabolic disease37. Obesity38. Haematology39. Haematological oncology40. Venous thromboembolic disease41. Malignant disease42. Infectious disease43. Sexually transmitted infections44. Human immunodeficiency virus45. DermatologyPART 5 MEDICINE THROUGHOUT LIFE46. Young adult medicine47. Sex and gender in medicine48. Obstetric medicine49. Medicine of the older adult50. Palliative care and symptom control