Diagnostic, Prognostic, and Therapeutic Role of MicroRNAs in Head and Neck Cancer

Early diagnosis of HNSCC can cause improved treatment, treatment response rates and reduction in mortality rates. Recently, miRNA-based diagnostics and therapeutics have gained considerable attention among the scientific community. MiRNAs are known to have great potential as biomarkers for early diagnosis, prediction, and prognosis of HNSCC, and play a role in development of targeted gene therapy.Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for diagnosis, prognosis, and treatment of HNSCC. It encompasses various miRNA-based point of care diagnostics and drug delivery systems for HNSCC along with the information on the clinical trials of miRNAs for improved clinical outcomes in HNSCC patients. The book provides a comprehensive overview of currently available miRNAs associated with HNSCC and their extensive application for early diagnosis, prognosis, and treatment. This book will help scientists and clinicians to win the battle against HNSCC.- Covers the role of the tumor microenvironment in head and neck cancer- Provides information on oncogenic and tumor suppressor miRNAs dysregulated in HNSCC patients- Elucidates the role of miRNAs in metastasis, recurrence, and chemoresistance in HNSCC- Includes the current state-of-art in miRNA-based clinical trials for head