Professor Peter Grieder is Professor Emeritus of the Physikalisches Institut, University of Bern. His research activities cover high energy phenomena, extensive air showers and neutrino astronomy. He developed the ASICO air shower simulation program system which later on was renamed CORSIKA that is widely used today with a variety of modern event generators, developed by many different authors. He was co-initiator together with Prof. Fred Reines, Nobel Laureate, and colleagues from other institutions of the pioneering DUMAND neutrino telescope project in Hawaii, which was the template for all presently existing and planned giant neutrino telescopes. He was also guest professor for many years at the University of Hawaii and is author of numerous scientific articles and several books. Teresa Montaruli is Professor of Astronomy at the University of Geneva working on high-energy multi-messenger astrophysics and in particular on the IceCube experiment, the Cherenkov Telescope Array and the LHAASO experiment. Prof Montaruli's earliest research was part of the MACRO experiment at Laboratori Nazionali del Gran Sasso. She also worked with the ANTARES neutrino detector in the Mediterranean Sea, the VERITAS gamma-ray telescope array in Arizona, and the High-Altitude Water Cherenkov Experiment in Mexico. In 2001, Prof Montaruli won the Shakti P. Duggal Award of the Commission on Cosmic Rays of the International Union of Pure and Applied Physics, for significant contributions to cosmic-ray physics. In 2009 she was named a Fellow of the American Physical Society for fundamental contributions, both experimental and theoretical, to the understanding of cosmic and atmospheric neutrino fluxes, neutrino mass, and the spectra of dark matter annihilations.

• 1. Motivation and Introduction2. The Evolution of Astronomy: from Visual to Neutrino Astronomy3. The Cosmic Radiation4. Interactions Relevant for Cosmic Ray Propagation5. Extensive Air Showers6. Anisotropy and Time Variation of the Cosmic Radiation7. Anisotropies at UH Energies, Point Sources and GZK Cutoff: Hadron Astronomy8. Interpretation of Cosmic Ray Data and Phenomena9. Propagation of Energetic Cosmic Rays in Space10. Sources of Ultrahigh Energy Cosmic Rays11. Muons and their Properties12. Neutrinos and their Properties13. Neutrino Production in Astrophysical Objects14. Neutrino Detection Methods and Telescope Types15. Ground, Balloon and Satellite Based Neutrino Telescopes16. Deep-Water/Ice Optical Cherenkov Neutrino Telescopes17. Radio Cherenkov Neutrino Telescopes18. Acoustic Detection of High Energy Neutrinos in Liquids and Solids19. Next Generation Telescopes20. Neutrino Astronomy Results21. Interpretation of Data and ConclusionsAppendixesA. The AtmosphereB. Galactic and Extragalactic Data Relevant for Cosmic RaysC. Heliospheric Data and RelationsD. Miscellaneous Data: FiguresE. Mathematical Methods, Relations and FormulasF. Complementary Relations, Data and TablesG. List of SymbolsH. Abbreviations and Acronyms

Professor Peter Grieder is Professor Emeritus of the Physikalisches Institut, University of Bern. His research activities cover high energy phenomena, extensive air showers and neutrino astronomy. He developed the ASICO air shower simulation program system which later on was renamed CORSIKA that is widely used today with a variety of modern event generators, developed by many different authors. He was co-initiator together with Prof. Fred Reines, Nobel Laureate, and colleagues from other institutions of the pioneering DUMAND neutrino telescope project in Hawaii, which was the template for all presently existing and planned giant neutrino telescopes. He was also guest professor for many years at the University of Hawaii and is author of numerous scientific articles and several books. Teresa Montaruli is Professor of Astronomy at the University of Geneva working on high-energy multi-messenger astrophysics and in particular on the IceCube experiment, the Cherenkov Telescope Array and the LHAASO experiment. Prof Montaruli's earliest research was part of the MACRO experiment at Laboratori Nazionali del Gran Sasso. She also worked with the ANTARES neutrino detector in the Mediterranean Sea, the VERITAS gamma-ray telescope array in Arizona, and the High-Altitude Water Cherenkov Experiment in Mexico. In 2001, Prof Montaruli won the Shakti P. Duggal Award of the Commission on Cosmic Rays of the International Union of Pure and Applied Physics, for significant contributions to cosmic-ray physics. In 2009 she was named a Fellow of the American Physical Society for fundamental contributions, both experimental and theoretical, to the understanding of cosmic and atmospheric neutrino fluxes, neutrino mass, and the spectra of dark matter annihilations.

• 1. Motivation and Introduction2. The Evolution of Astronomy: from Visual to Neutrino Astronomy3. The Cosmic Radiation4. Interactions Relevant for Cosmic Ray Propagation5. Extensive Air Showers6. Anisotropy and Time Variation of the Cosmic Radiation7. Anisotropies at UH Energies, Point Sources and GZK Cutoff: Hadron Astronomy8. Interpretation of Cosmic Ray Data and Phenomena9. Propagation of Energetic Cosmic Rays in Space10. Sources of Ultrahigh Energy Cosmic Rays11. Muons and their Properties12. Neutrinos and their Properties13. Neutrino Production in Astrophysical Objects14. Neutrino Detection Methods and Telescope Types15. Ground, Balloon and Satellite Based Neutrino Telescopes16. Deep-Water/Ice Optical Cherenkov Neutrino Telescopes17. Radio Cherenkov Neutrino Telescopes18. Acoustic Detection of High Energy Neutrinos in Liquids and Solids19. Next Generation Telescopes20. Neutrino Astronomy Results21. Interpretation of Data and ConclusionsAppendixesA. The AtmosphereB. Galactic and Extragalactic Data Relevant for Cosmic RaysC. Heliospheric Data and RelationsD. Miscellaneous Data: FiguresE. Mathematical Methods, Relations and FormulasF. Complementary Relations, Data and TablesG. List of SymbolsH. Abbreviations and Acronyms

Professor Peter Grieder is Professor Emeritus of the Physikalisches Institut, University of Bern. His research activities cover high energy phenomena, extensive air showers and neutrino astronomy. He developed the ASICO air shower simulation program system which later on was renamed CORSIKA that is widely used today with a variety of modern event generators, developed by many different authors. He was co-initiator together with Prof. Fred Reines, Nobel Laureate, and colleagues from other institutions of the pioneering DUMAND neutrino telescope project in Hawaii, which was the template for all presently existing and planned giant neutrino telescopes. He was also guest professor for many years at the University of Hawaii and is author of numerous scientific articles and several books. Teresa Montaruli is Professor of Astronomy at the University of Geneva working on high-energy multi-messenger astrophysics and in particular on the IceCube experiment, the Cherenkov Telescope Array and the LHAASO experiment. Prof Montaruli's earliest research was part of the MACRO experiment at Laboratori Nazionali del Gran Sasso. She also worked with the ANTARES neutrino detector in the Mediterranean Sea, the VERITAS gamma-ray telescope array in Arizona, and the High-Altitude Water Cherenkov Experiment in Mexico. In 2001, Prof Montaruli won the Shakti P. Duggal Award of the Commission on Cosmic Rays of the International Union of Pure and Applied Physics, for significant contributions to cosmic-ray physics. In 2009 she was named a Fellow of the American Physical Society for fundamental contributions, both experimental and theoretical, to the understanding of cosmic and atmospheric neutrino fluxes, neutrino mass, and the spectra of dark matter annihilations.

• 1. Motivation and Introduction2. The Evolution of Astronomy: from Visual to Neutrino Astronomy3. The Cosmic Radiation4. Interactions Relevant for Cosmic Ray Propagation5. Extensive Air Showers6. Anisotropy and Time Variation of the Cosmic Radiation7. Anisotropies at UH Energies, Point Sources and GZK Cutoff: Hadron Astronomy8. Interpretation of Cosmic Ray Data and Phenomena9. Propagation of Energetic Cosmic Rays in Space10. Sources of Ultrahigh Energy Cosmic Rays11. Muons and their Properties12. Neutrinos and their Properties13. Neutrino Production in Astrophysical Objects14. Neutrino Detection Methods and Telescope Types15. Ground, Balloon and Satellite Based Neutrino Telescopes16. Deep-Water/Ice Optical Cherenkov Neutrino Telescopes17. Radio Cherenkov Neutrino Telescopes18. Acoustic Detection of High Energy Neutrinos in Liquids and Solids19. Next Generation Telescopes20. Neutrino Astronomy Results21. Interpretation of Data and ConclusionsAppendixesA. The AtmosphereB. Galactic and Extragalactic Data Relevant for Cosmic RaysC. Heliospheric Data and RelationsD. Miscellaneous Data: FiguresE. Mathematical Methods, Relations and FormulasF. Complementary Relations, Data and TablesG. List of SymbolsH. Abbreviations and Acronyms