Biology of Aging Accelerators

Dr. Sandeep Kumar Singh is Assistant Professor in the All India Institute of Medical Sciences (AIIMS), Nagpur, India. He obtained his PhD in Biotechnology from Banaras Hindu University and conducted postdoctoral research in the Department of Neurobiology at the University of Chicago. Dr. Singh brings 17 years of experience in neuroscience, molecular biology, neurodegenerative diseases, aging, nutraceuticals, and nanomedicines. He is a member of several scientific societies, including the American Academy of Neurology, International Society of Neurochemistry, Society of Neurochemistry, Indian Academy of Neurosciences, and Alzheimer’s and related Disorders Society of India. Dr. Singh has published five books, including Elsevier’s A New Era in Alzheimer’s Research and Genome Editing for Neurodegenerative Diseases.Shailendra Kumar Mishra is co-founder of Indian Scientific Education and Technology (ISET) Foundation, a non-profit/non-governmental organization that persuades toward the science promotion. He is Molecular Human Genetics postgraduate, skilled in DNA Sequencing, Polymerase Chain Reaction (PCR), DNA & Plasmid isolation, Gel electrophoresis, Molecular hybridization, DNA elution from agarose gel, bacterial transformation, quantitation of DNA, DNA sequencing technique and versed in various diagnostic techniques. He did Master of Science in Molecular and Human Genetics from Jiwaji University, India, and research project from Banaras Hindu University, India. He has published his articles in some international and national journals such as Journal of Alzheimer’s Disease and Parkinsonism and Nature India. His major interest is to understand the aging process through molecular basis that could be beneficial to cure age-related diseases.

• 1. Aging: Concept of Biological Aging, Historical Perspective, and Impact of Aging on Health and Society2. Hallmarks of Aging: Exhibiting Characteristics That May or May Not Contribute to Accelerated Aging3. Aging Accelerators: Basic Concept, Key Accelerators in Human Biology, and Molecular Basis of Aging Accelerators4. Biological Clocks and Accelerated Aging: Understanding the Timers of Life5. Mechanisms of Aging Accelerators: Cellular Senescence, DNA Damage, Epigenetic Changes, Mitochondrial Dysfunction, and Stem Cell Exhaustion6. Diverse Timelines: How Different Organs Age at Different Rates7. Accelerated Aging: The Brain's Role as the Body's Aging Integrator8. Oxidative Stress: How It Accelerates Aging9. Obesity Accelerates Aging10. Chronic Inflammation as an Accelerator of Aging11. Stress, Anxiety Disorder, and Depression Accelerate Aging12. Physical and Environmental Factors Accelerate Aging13. Role of Socioeconomic, Social, Demographic, and Biological Factors in Accelerating Aging14. Dietary and Lifestyle Factors Accelerate Aging15. Mitogenic Factors Accelerate Aging16. Vitamin D Deficiency as Potential Factor to Accelerate Aging17. Pharmacological and Nutraceutical Interventions to Prohibit Accelerated Aging18. Lifestyle Modification and Dietary Supplements to Prevent Accelerated Aging19. SIRTain Regulators of Accelerated Aging20. Regenerative Medicine and Genetic Therapies as Regulators of Accelerated Aging21. Current Research Trends, Emerging Technologies, and Future Directions for Prevention of Accelerated Aging