Sandeep Kumar Singh – författare
1 580 kr
Skickas inom 10-15 vardagar
1 567 kr
Skickas inom 10-15 vardagar
1 654 kr
Skickas inom 10-15 vardagar
Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.
Discusses underlying cellular and molecular mechanisms altered in protein-associated neurodegenerative disordersDescribes methods for detection and analysis of protein aggregatesFeatures advancements in therapeutics and emerging techniques to treat these disordersCovers implications in a variety of neurodegenerative diseases, including Alzheimer's, Parkinson’s, ALS, Creutzfeldt-Jakob disease, Cystic fibrosis, Gaucher's disease, and Polyglutamine diseases, including Huntington’s and other related proteinopathies1 967 kr
Skickas inom 10-15 vardagar
Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases.
Covers basic mechanisms of genome-editing tools and their therapeutic potentialHighlights current research progress and the therapeutic strategies to use genome-editing tools against neurodegenerative diseases
Includes research on genome-editing tool development from the basic concept to clinical trials
1 716 kr
Kommande
1 426 kr
Skickas inom 10-15 vardagar
1 716 kr
Skickas inom 10-15 vardagar
1 963 kr
Skickas inom 10-15 vardagar
1 702 kr
Kommande
1 653 kr
Kommande
1 786 kr
Skickas inom 5-8 vardagar
2 158 kr
Skickas inom 10-15 vardagar
131 kr
Skickas inom 5-8 vardagar