Approx.280 pages- Discusses underlying cellular and molecular mechanisms altered in protein-associated neurodegenerative disorders- Describes methods for detection and analysis of protein aggregates- Features advancements in therapeutics and emerging techniques to treat these disorders- Covers implications in a variety of neurodegenerative diseases, including Alzheimer''s, Parkinson''s, ALS, Creutzfeldt-Jakob disease, Cystic fibrosis, Gaucher''s disease, and Polyglutamine diseases, including Huntington''s and other related proteinopathies