Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.

Discusses underlying cellular and molecular mechanisms altered in protein-associated neurodegenerative disordersDescribes methods for detection and analysis of protein aggregatesFeatures advancements in therapeutics and emerging techniques to treat these disordersCovers implications in a variety of neurodegenerative diseases, including Alzheimer's, Parkinson’s, ALS, Creutzfeldt-Jakob disease, Cystic fibrosis, Gaucher's disease, and Polyglutamine diseases, including Huntington’s and other related proteinopathies

Approx.280 pages- Discusses underlying cellular and molecular mechanisms altered in protein-associated neurodegenerative disorders- Describes methods for detection and analysis of protein aggregates- Features advancements in therapeutics and emerging techniques to treat these disorders- Covers implications in a variety of neurodegenerative diseases, including Alzheimer''s, Parkinson''s, ALS, Creutzfeldt-Jakob disease, Cystic fibrosis, Gaucher''s disease, and Polyglutamine diseases, including Huntington''s and other related proteinopathies

Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest research findings, shedding light on the mechanisms by which heavy metals cause neuronal damage and contribute to disease progression. By integrating various perspectives and collating diverse studies, this book serves as an invaluable resource for those seeking to understand the profound impact of heavy metals on neurological health. In addition to detailing the mechanisms involved, the book highlights the importance of early detection and preventive measures.It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease.Provides a comprehensive overview of how heavy metals interact with biological systems, particularly the nervous systemExplains the mechanisms through which metals contribute to neurodegenerative diseasesHighlights the public health implications of heavy metal exposure, including its impact on vulnerable populations such as children and older people

Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest research findings, shedding light on the mechanisms by which heavy metals cause neuronal damage and contribute to disease progression. By integrating various perspectives and collating diverse studies, this book serves as an invaluable resource for those seeking to understand the profound impact of heavy metals on neurological health. In addition to detailing the mechanisms involved, the book highlights the importance of early detection and preventive measures.It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease. - Provides a comprehensive overview of how heavy metals interact with biological systems, particularly the nervous system- Explains the mechanisms through which metals contribute to neurodegenerative diseases- Highlights the public health implications of heavy metal exposure, including its impact on vulnerable populations such as children and older people

Pesticides and Neurotoxicant Exposures: Impacts of Neurodevelopment and Long-Term Brain Health explores neuroscience research, revealing how chronic pesticide exposure contributes to neurodegenerative diseases and cognitive decline. This new volume synthesizes findings on the mechanisms of pesticide-induced neurotoxicity and its impact on brain health. Targeted at researchers, clinicians, and policymakers, the book explores gaps in knowledge and the urgent need for improved regulation to protect vulnerable populations. By bridging scientific insights with public health, the book aims to advance understanding and prevention of pesticide-related neurological disorders.Identifies the link between pesticides and neurological disordersExplores research, risk assessment tools, and practical strategies for understanding, monitoring, and mitigating pesticides' neurotoxic effectsProvides a comprehensive and interdisciplinary approach to understanding pesticides and neurotoxicityOffers case studies, relating scientific research to real world applications

Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.

Discusses underlying cellular and molecular mechanisms altered in protein-associated neurodegenerative disordersDescribes methods for detection and analysis of protein aggregatesFeatures advancements in therapeutics and emerging techniques to treat these disordersCovers implications in a variety of neurodegenerative diseases, including Alzheimer's, Parkinson’s, ALS, Creutzfeldt-Jakob disease, Cystic fibrosis, Gaucher's disease, and Polyglutamine diseases, including Huntington’s and other related proteinopathies

Approx.280 pages- Discusses underlying cellular and molecular mechanisms altered in protein-associated neurodegenerative disorders- Describes methods for detection and analysis of protein aggregates- Features advancements in therapeutics and emerging techniques to treat these disorders- Covers implications in a variety of neurodegenerative diseases, including Alzheimer''s, Parkinson''s, ALS, Creutzfeldt-Jakob disease, Cystic fibrosis, Gaucher''s disease, and Polyglutamine diseases, including Huntington''s and other related proteinopathies

Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest research findings, shedding light on the mechanisms by which heavy metals cause neuronal damage and contribute to disease progression. By integrating various perspectives and collating diverse studies, this book serves as an invaluable resource for those seeking to understand the profound impact of heavy metals on neurological health. In addition to detailing the mechanisms involved, the book highlights the importance of early detection and preventive measures.It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease.Provides a comprehensive overview of how heavy metals interact with biological systems, particularly the nervous systemExplains the mechanisms through which metals contribute to neurodegenerative diseasesHighlights the public health implications of heavy metal exposure, including its impact on vulnerable populations such as children and older people

Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest research findings, shedding light on the mechanisms by which heavy metals cause neuronal damage and contribute to disease progression. By integrating various perspectives and collating diverse studies, this book serves as an invaluable resource for those seeking to understand the profound impact of heavy metals on neurological health. In addition to detailing the mechanisms involved, the book highlights the importance of early detection and preventive measures.It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease. - Provides a comprehensive overview of how heavy metals interact with biological systems, particularly the nervous system- Explains the mechanisms through which metals contribute to neurodegenerative diseases- Highlights the public health implications of heavy metal exposure, including its impact on vulnerable populations such as children and older people

Pesticides and Neurotoxicant Exposures: Impacts of Neurodevelopment and Long-Term Brain Health explores neuroscience research, revealing how chronic pesticide exposure contributes to neurodegenerative diseases and cognitive decline. This new volume synthesizes findings on the mechanisms of pesticide-induced neurotoxicity and its impact on brain health. Targeted at researchers, clinicians, and policymakers, the book explores gaps in knowledge and the urgent need for improved regulation to protect vulnerable populations. By bridging scientific insights with public health, the book aims to advance understanding and prevention of pesticide-related neurological disorders.Identifies the link between pesticides and neurological disordersExplores research, risk assessment tools, and practical strategies for understanding, monitoring, and mitigating pesticides' neurotoxic effectsProvides a comprehensive and interdisciplinary approach to understanding pesticides and neurotoxicityOffers case studies, relating scientific research to real world applications