Pesticides and Neurotoxicant Exposures

Dr. Gogia is a Post-Doctoral Associate at Yale. Having completed her PhD degree at the University of Dayton, and Cornell University’s International Agriculture and Rural Development Program (IARD) she was awarded the Gerald L. Willis Award of Excellence for Outstanding Teaching in 2019. Her current work focuses on understanding cellular and molecular mechanisms underlying polyglutamine diseases, namely the identification and validation of genetic modifiers which can serve as potential therapeutic targets and can ameliorate the onset or progression of neurodegenerative diseases. Dr. Prasann Kumar, assistant professor cum research intensive faculty in theDepartment of Agronomy, School of Agricultural (ICAR-Accredited), LovelyProfessional University, Punjab, specializes in stress physiology, plant tissue culture,physiology of plant?microbe/pathogen interaction, and biodiversity management.Dr. Kumar has completed the International Agricultural Rural DevelopmentProgramme from Cornell University, Ithaca, New York, United States. He hasreceived a doctorate from Banaras Hindu University, Varanasi. He also hasauthored 40 books published by national and international publishers, which finda place in national as well as various Overseas Institutions’ libraries. He hasguided 19 MSc students for their thesis.

• Section 1: Introduction to Pesticides and Neurotoxicity1. Pesticides and Human Health: An Overview2. Neurotoxic Effects of Pesticides: Mechanisms and Pathways3. Classification of Pesticides and Their Neurotoxic Potential4. Routes of Pesticide Exposure and Bioaccumulation5. Epidemiological Evidence of Pesticide-Induced NeurotoxicitySection 2: Pesticides Classes and Their Neurotoxic Effects6. Organophosphates and Acetylcholinesterase Inhibition7. Carbamates: Mechanisms of Neurotoxicity8. Organochlorines and Their Impact on the Nervous System9. Pyrethroids: Effects on Ion Channels and Neurotransmission10. Neonicotinoids and Their Influence on the Central Nervous System11. Herbicides and Neurodegeneration: The Case of Paraquat and Glyphosate12. Fungicides and Neurotoxicity: A Neglected Risk?13. Rodenticides and Their Impact on Brain Function14. Biopesticides: Safer Alternatives or Hidden Neurotoxins?Section 3: Cellular and Molecular Mechanisms of Pesticide-Induced Neurotoxicity15. Oxidative Stress, Reactive oxygen species and Mitochondrial Dysfunction in Pesticide Toxicity16. Neuroinflammation and Glial Cell Activation in Pesticide Exposure17. Neurotransmitter Dysregulation Induced by Pesticides18. Epigenetic Modifications in Pesticide-Induced Neurotoxicity19. Blood-Brain Barrier Disruption Mechanisms by Pesticides20. Autophagy, Apoptosis, and Cell Death Pathways in Pesticide ToxicitySection 4: Pesticides and Neurodevelopmental Disorders21. Prenatal and Early-Life Pesticide Exposure: Impacts on Brain Development22. Pesticides and Autism Spectrum Disorders: Evidence and Mechanisms23. Attention Deficit Hyperactivity Disorder (ADHD) and Pesticide Exposure24. Pesticides and Cognitive Impairments in ChildrenSection 5: Pesticides and Neurodegenerative Diseases25. Pesticides and Alzheimer’s Disease: Risk Factors and Mechanisms26. Parkinson’s Disease and Pesticide Exposure: A Strong Association?27. Amyotrophic Lateral Sclerosis (ALS) and Neurotoxicity of Pesticides28. Multiple Sclerosis and Pesticides: Possible LinksSection 6: Biomarkers and Detection of Pesticide-Induced Neurotoxicity29. Biomarkers of Pesticide Exposure in the Nervous System30. Neuroimaging, Computational and Artificial Intelligence Approaches in Pesticide Toxicity Assessment31. Advances in Toxicogenomics for Evaluating Pesticide-Induced NeurotoxicitySection 7: Mitigation Strategies and Future Directions32. Precision agriculture and Artificial Intelligence driven pest management to reduce pesticide dependency33. Detoxification Pathways and Neuroprotection Against Pesticides34. Dietary and Nutritional Interventions for Reducing Neurotoxic Effects35. Regulatory Policies and Risk Assessment of Neurotoxic Pesticides36. Eco-Friendly Alternatives: Reducing the Neurotoxic Burden of Pesticides37. Public Awareness and Education on Pesticide Neurotoxicity38. Novel Therapeutic Strategies for Pesticide-Induced Neurotoxicity39. Innovations in Pesticide Formulation for Reduced Neurotoxicity40. Artificial Intelligence and Big Data in Neurotoxicology Research41. Future Perspectives on Pesticide Use and Neurotoxic Risks