Häftad, Engelska, 2024
Genome Editing for Neurodegenerative Diseases
From Concept to Clinical Trials
Av Sandeep Kumar Singh, Amarish Kumar Yadav, Burkhard Poeggeler, George Perry
2084 kr
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Beskrivning
Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases.
- Covers basic mechanisms of genome-editing tools and their therapeutic potential
- Highlights current research progress and the therapeutic strategies to use genome-editing tools against neurodegenerative diseases
- Includes research on genome-editing tool development from the basic concept to clinical trials
Produktinformation
- Utgivningsdatum: 2024-10-18
- Mått: 152 x 229 x 15 mm
- Vikt: 420 g
- Format: Häftad
- Språk: Engelska
- Antal sidor: 260
- Förlag: Elsevier Science
- ISBN: 9780443238260
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Dr. Sandeep Kumar Singh is Assistant Professor in the All India Institute of Medical Sciences (AIIMS), Nagpur, India. He obtained his PhD in Biotechnology from Banaras Hindu University and conducted postdoctoral research in the Department of Neurobiology at the University of Chicago. Dr. Singh brings 17 years of experience in neuroscience, molecular biology, neurodegenerative diseases, aging, nutraceuticals, and nanomedicines. He is a member of several scientific societies, including the American Academy of Neurology, International Society of Neurochemistry, Society of Neurochemistry, Indian Academy of Neurosciences, and Alzheimer’s and related Disorders Society of India. Dr. Singh has published five books, including Elsevier’s A New Era in Alzheimer’s Research and Genome Editing for Neurodegenerative Diseases.Dr. Amarish K Yadav is a postdoctoral research scholar at North Carolina State University. His current research interest is developing gene-drive systems using CRISPR/Cas9 in Drosophila suzukii. After obtaining his master’s degree in biotechnology, he was awarded his Ph.D. from Banaras Hindu University in 2017. He has worked in collaboration with many neuroscientists and researchers to understand the molecular mechanisms of Alzheimer’s and Parkinson’s diseases progression and therapeutics. Dr. Yadav has published his research findings in peer-reviewed journals and has also authored a book chapter on neurodegenerative diseases modeling in drosophila. Dr. Yadav has participated and presented his research work at various national and international conferences and symposia. Dr. Burkhard Poeggeler (Georg-August-University of Göttingen, Germany) holds a PhD in Biochemistry and has authored over 120 PubMed-indexed publications. His research focuses on neuroprotection, redox biology, and regenerative pharmacology. Dr. George Perry, Ph.D. Professor of Biology and Chemistry Semmes Foundation Distinguished University Chair in Neurobiology He is a neuroscientist known for his work on neuronal oxidation of nucleic acids in Alzheimer's disease. He is distinguished as one of the top Alzheimer’s disease researchers with over 1000 publications, won numerous awards, and is one of the top 100 most-cited scientists.
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