ATP: From Neurotransmission to Cancer Therapy delivers a comprehensive discussion of extracellular ATP biology and its communication role in both homeostasis and pathologic states. It explores the function of ATP across the nervous, sensory, musculoskeletal, cutaneous cardiovascular, pulmonary, gastrointestinal, urinary, reproductive, exocrine, haematopoietic and immune systems. The book considers ATP in the context of various disease states, including cardiovascular, respiratory, psychiatric, inflammatory and neurodegenerative disorders, as well as pain and sensory disorders, infectious diseases, and cancer. ATP in humans is explored alongside other species, including rodents, fish, and plants. This is the latest volume in the "e;Molecular Mediators in Health and Disease"e; series. With contributions from specialists across pharmacology, physiology, biophysics, biochemistry, immunology, anatomy, molecular biology, therapeutics, and other critical fields, this volume provides a broad and detailed overview of ATP which will be helpful to researchers working in these areas and beyond. - Considers extracellular ATP across various organs including the lung, heart, liver and kidneys- Investigates ATP across a range of conditions such as age-related disorders, cardiovascular disease, respiratory disease and psychiatric disorders- Explores the biochemistry and molecular biology of extracellular ATP signalling- Looks at the history of ATP and its discovery in addition to future perspectives
