Nyhet

NERVE GROWTH FACTOR

From Neuron Development to Neurology

AvAntonino Cattaneo,Simona Capsoni

Häftad, Engelska, 2026

Del i serien Molecular Mediators in Health and Disease: How Cells Communicate

1 741 kr

Kommande

Beskrivning

Nerve growth factor: From Neuron Development to Neurology, the latest release in the Molecular Mediators in Health and Disease series, offers a complete guide to nerve growth factor (NGF) across health and disease. Sections cover key properties, the latest advances, and biomedical applications of this neuropeptide. The book begins with an introduction and historical overview of the discovery of NGF before exploring its molecular characteristics. It then covers NGF in organ function, with chapters discussing the brain, immune system, blood vessels, heart, reproductive organs, teeth, and lungs. NGF pharmacology is then considered, with a focus on NGF as a therapeutic agent.

The final section of the book covers NGF across diseases, including Alzheimer’s disease, cancer, diseases of the eye, chronic pain, and visceral disfunctions. Throughout the book, NGF is considered in the context of both mammalian and non-mammalian biology, making it an ideal reference for researchers working across the fields of cell biology, molecular biology, pharmacology, and other biomedical areas.

Explores the pathways of NGF, its receptors, and physiological functions
Covers NGF in disease, including neurodegenerative disease and cancer
Considers the therapeutic potential of NGF

Produktinformation

Utgivningsdatum:2026-10-01
Mått:191 x 235 x undefined mm
Vikt:450 g
Format:Häftad
Språk:Engelska
Serie:Molecular Mediators in Health and Disease: How Cells Communicate
Antal sidor:480
Förlag:Elsevier Science
ISBN:9780443330889

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Mer om författaren

Antonino Cattaneo is currently Professor of Neurobiology at the Scuola Normale Superiore (Pisa), Italy, where he is the Director of the Biology Lab Bio@SNS. He is the author of numerous publications in peer-reviewed international journals and is recipient of several awards including Domenico Marotta Prize, Italian Academy of Sciences XL, the W. Jansenius Medal, Slovak Academy of Sciences and the “G. Tartufari International Prize for Biology, Accademia Nazionale dei Lincei.He is a member of EMBO (European Molecular Biology Organization) and the Italian Academy of Sciences XL.He is former member of the Council of Scientists of Human Frontier Science Program Organization (HFSPO), for which he has also served for four years as the Chairman of the Grants Review Committee. He has been Visiting Fellow of Trinity College in Cambridge (UK). He is a Team Leader of the European Neuroscience Institute Young Investigator Network.Simona Capsoni has served as Associate Professor of Physiology at University of Ferrara and Scuola Normale Superiore since 2016. Prior to this, in 2010 she joined the Bio@SNS Laboratory of Biology at Scuola Normale Superiore in Pisa (Italy) as contract junior professor where she discovered that NGF and hNGFp can affect the pathophysiology of glial cells, in particular microglia. At the same time, she started the line of research on NGF signalling system in painlessness diseases. She has published numerous papers and her primary research area focuses on the therapeutic application of hNGFp.

Innehållsförteckning

Part I - Introduction to Nerve Growth1. History of Nerve Growth2. Nerve Growth Factor in Normal BiologyPart II – Molecular biology of Nerve Growth3. Production and structure of Nerve Growth4. Measurement of Nerve Growth Factor and its precursor5. Nerve Growth Factor receptorsPart III – Nerve Growth Factor in organ function6. NGF in sensory and sympathetic neurons7. NGF in Brain8. NGF and the immune system9. NGF in blood vessels and heart10. NGF in reproductive organs11. NGF in teeth12. Nerve Growth Factor and the Lung.Part IV – Nerve Growth Factor pharmacology13. TrkA mimetics14. P75NTR receptor blockers15. Antibodies neutralizing NGF or TrkA16. Nerve Growth Factor protein as a therapeutic agentPart V – NGF in non-mammalian biology17. NGF in non-mammalian organismsPart VI - Nerve Growth Factor in Disease18. Nerve Growth Factor and Alzheimer’s disease19. Nerve Growth Factor and diseases of the eye20. Nerve Growth factor and cancer21. Nerve Growth Factor and chronic pain22. Nerve Growth Factor and visceral disfunctions