Zodwa Dlamini is a Professor of Molecular Oncology and the founding Director and the Executive Head of the Pan African Cancer Research Institute (PACRI) in South Africa. She is the Director of South African Medical Research Council (SAMRC) Precision Oncology Research Unit (PORU). She is the DSI/NRF SARChI Chair in Precision Oncology and Cancer Prevention (POCP). She is a member of the American Association for Cancer Research (AACR) Advisory Group on Sub-Saharan Africa. She is a member of the AACR Pathology Resources in Africa Advisory Group. Professor Dlamini is a member of the African Organisation for Research and Training in Cancer (AORTIC) Research Committee Scientific Advisory Board. She is an elected member of the Academy of Science of South Africa. Professor Dlamini is an overseas Fellow of the Royal Society of Medicine (London). She is the Associate Editor for Frontiers in Oncology: Cancer Genetics Section

• Part 1: Understanding Colorectal Cancer Drug Resistance1. Unraveling the Mystery of Treatment Resistance in colorectal cancer2. Mechanisms of Treatment Resistance in Colorectal Cancer3. Biomarkers and Predictive Factors in Colorectal Cancer Treatment Resistance4. Targeted Therapies and Precision Medicine in Colorectal Cancer Drug ResistancePart 2: Innovative Approaches to Overcoming Drug Resistance5. Overcoming Chemotherapy Resistance in Colorectal Cancer6. Emerging Treatment Approaches for Colorectal Cancer Treatment Resistance7. Immunotherapy and Immunomodulation in Colorectal Cancer Treatment Resistance8. Splicing-Associated Drug Resistance in colorectal cancer: Targeting splicing signatures9. Nanomedicine Innovations: Conquering Colorectal Cancer Drug ResistancePart 3: Molecular Factors and Therapeutic Strategies10. MicroRNAs in Colorectal Cancer Drug Resistance11. Long Non-coding RNAs and Drug Resistance in Colorectal Cancer12. Surgical Interventions and Minimally Invasive Techniques in Treatment-resistant Colorectal Cancer13. Clinical Trials and Research Advances in Colorectal Treatment ResistancePart 4: Future Perspectives and Advanced Research14. Artificial Intelligence and Colorectal Cancer Drug Resistance15. Microbiome and Colorectal Cancer Drug Resistance16. Virally Induced Colorectal Cancer Drug Resistance17. Future Horizons and Hope in Colorectal Cancer Drug Resistance