Zodwa Dlamini – författare

Navigating Head and Neck Cancer offers an in-depth, multidimensional exploration of head and neck cancer, designed to provide crucial insights for healthcare professionals, researchers, and students. Beginning with a solid foundation in the epidemiology of head and neck cancer, the book then transitions to discussing the latest technological advancements in diagnosis and treatment. Emphasizing a holistic approach, it delves into comprehensive cancer care with a focus on survivorship and quality of life considerations. The book also highlights the psychosocial impacts of head and neck cancer, advocating for the integration of palliative care to address the full spectrum of patient needs.One of the book's strengths is its global perspective, which examines preventive strategies and disparities in access to care across different regions. Contributions from leading experts worldwide ensure a rich and diverse understanding of the challenges and innovations in the field. The book concludes with a forward-looking discussion on emerging technologies and future directions in head and neck cancer management. It explores cutting-edge research areas, such as precision medicine, immunotherapy, and artificial intelligence, setting the stage for future breakthroughs.Through this collaborative effort, Navigating Head and Neck Cancer not only informs but also inspires continued research and innovation, making it an indispensable resource for anyone involved in the fight against head and neck cancer.

Strategies for Overcoming Chemotherapy Resistance in Cervical Cancer: From Molecular Insights to Precision Solutions, Volume 21 highlights different strategies to reverse chemotherapy resistance in cervical cancer. The book puts a strong focus on strategies to reverse chemotherapy resistance as well as strategies for early detection of the resistance, enhancing precision oncology in terms of patient care and maximizing patient management. The book also looks at virally induced resistance to chemotherapy and recommends combination therapies that can maximize the reversal of this resistance.In 10 chapters, the book not only gives an overview of cervical cancer and chemotherapy as treatment, but also investigates resistance to chemotherapy and treatment for resistance. It defines treatment mechanisms, options, and limitations to beat chemotherapy resistance and the reversal of the resistance mechanisms. It gives insights into future directions of cervical cancer treatment using epigenetic silencing, chemotherapy splicing, the involvement of MicroRNAs to chemotherapy resistance, and the application of Artificial Intelligence.Discusses strategies to reverse and detect resistance to chemotherapy at an early stageInvestigates the applications of Artificial Intelligence in the study of cervical chemotherapy resistancePresents research and applications developed to overcome cancer resistance

Colorectal Cancer Treatment Resistance: Mechanisms, Insights, Advances and Solutions provide insights, knowledge, and potential solutions for healthcare professionals, researchers, and individuals affected by colorectal cancer. The book discusses innovative therapies, personalized medicine, and the latest scientific advancements in the field, all aimed at enhancing the effectiveness of treatment and improving the prognosis for colorectal cancer patients. It elucidates on the broader context of cancer research and treatment strategies that have the potential to impact the overall approach to managing colorectal cancer and, by extension, other types of cancer that may exhibit similar resistance challenges.By studying and addressing resistance mechanisms, researchers and healthcare professionals can work towards improving patient outcomes and the overall quality of cancer care.Focuses on the challenges and strategies associated with overcoming treatment resistance in colorectal cancerExplores the various factors contributing to treatment resistance, such as genetic mutations, tumor heterogeneity, and the tumor microenvironmentDiscusses the different treatment modalities and approaches used in colorectal cancer therapy and how they can be adapted to overcome resistance

The Exposome in Cancer Disparities: Influence of Environmental and Infectious Factors in LMICs examines how environmental and infectious factors drive cancer inequities in low- and middle-income countries (LMICs). The book introduces the exposome as a comprehensive framework to understand complex risk factors, such as environmental toxins, climate change, and infectious agents like HPV and HIV. The book combines scientific insights, real-world case studies, and practical strategies from international experts, highlighting region-specific contributors to cancer disparities. Structured into thematic sections, it offers a holistic view of the challenges faced by LMICs and provides actionable, evidence-based solutions tailored to resource-limited settings.The work emphasizes the importance of multidisciplinary approaches and international collaboration to develop effective prevention and policy strategies. It will benefit researchers, policymakers, and healthcare professionals by deepening understanding of cancer risk factors, fostering global cooperation and guiding targeted interventions to reduce health inequities and improve outcomes worldwide.Introduces the exposome as a transformative framework for understanding the complex interplay of environmental and infectious factors in cancer disparitiesIntegrates scientific insights, case studies, and practical strategies from international experts to provide a holistic and actionable perspectiveEmphasizes the importance of multidisciplinary approaches and international collaboration to develop effective prevention and policy interventions in resource-limited settings

Advancing Brain Cancer Care: Precision, AI Innovation, and African Insights delves into the intricate challenges of brain tumor management, offering cutting-edge solutions tailored to individual patients. Emphasizing the African perspective, it explores the use of innovative technologies to bridge care gaps and improve outcomes in underserved regions. By combining science, technology, and regional expertise, the book offers hope for patients and practitioners alike. Beyond its focus on brain tumor care, the book highlights the ethical considerations of AI integration into healthcare systems. It examines how precision medicine can reshape treatment pathways while addressing inequities in global access to care.Additionally, it provides a deep dive into collaborative efforts across continents, showcasing case studies and actionable insights that push the boundaries of conventional healthcare solutions. This vital resource is both an inspiration and a guide for those committed to advancing cancer care worldwide.Emphasizes the transformative role of precision medicine and artificial intelligence (AI) in tailoring brain tumor treatmentsAddresses critical aspects of brain tumor management, including diagnostics, therapeutic innovations, neurosurgical techniques, and the application of emerging technologies like nanomedicineHighlights unique challenges and opportunities within the African context, ensuring that the content is relevant to both global and local audiences

Precision Oncology in Liver Cancer: Genomics, Infection, and the Exposome in African and Global Contexts explores liver cancer through the lens of precision medicine, integrating molecular profiling, environmental exposures, and targeted therapies. The book presents a multidisciplinary approach, covering infectious drivers like HBV/HCV, environmental carcinogens such as aflatoxins, and emerging tools including genomics, AI, and liquid biopsies. It emphasizes African-specific challenges and innovations, with case studies and comparative global insights. This volume equips researchers, clinicians, and policymakers with evidence-based strategies to address liver cancer disparities, offering a forward-looking framework for equitable cancer care and research in Africa and globally.Integrates infection, genomics, and exposome science to provide a holistic understanding of liver cancer etiology and progressionPresents African case studies alongside global comparisons to contextualize challenges and showcase regionally relevant solutionsIncludes future-focused chapters on AI, multi-omics, and ethical frameworks to guide innovation and equitable implementation

This book explores the relationship between the gut microbiome and cancer, illuminating various facets from fundamental roles to personalized therapies. It provides a comprehensive overview of the impact of the gut microbiome on cancer development, offering potential for innovative diagnostic and treatment approaches. The book discusses the role of dysbiosis in cancer development, the influence of the microbiome on treatment responses, and strategies to modulate the microbiome for enhanced therapies. It reviews the influence of the gut microbiome on immunotherapy resistance and chemoresistance in cancer patients. Additionally, the book presents gut microbiome biomarkers for cancer diagnosis and prognosis, the implication of the gut-brain axis on cancer development and progression, and the impact of diet and lifestyle on the microbiome. Towards the end, the book investigates the role of the gut microbiome in pediatric cancer and provides an outlook on the future challenges, technological advancements, and ethical considerations of gut microbiome research in the context of personalized cancer therapies. This book is intended for cancer researchers, medical oncologists, clinicians, pharmacologists, translational investigators, and medical students.

This book delves into the complexities of melanoma, offering an in-depth examination of the disease alongside the latest advancements in diagnosis and treatment. The initial chapter provides a comprehensive overview of melanoma, covering its fundamentals and introducing the latest technologies shaping the understanding of the disease. The book introduces advanced molecular diagnostics in identifying targetable mutations and tailoring therapies for personalized and effective melanoma treatment. Additionally, it investigates the role of artificial intelligence in melanoma diagnostics and the advancements in imaging technologies for the monitoring and assessment of melanoma. It also reviews novel, innovative immunotherapeutic approaches designed to enhance the body's immune response against melanoma cells. Further, the book delves into the development and application of targeted therapies and nanomedicine in treating melanoma. A dedicated chapter highlights the advantages of a multi-omics approach, integrating genomic, proteomic, and other omics data to achieve a holistic understanding of melanoma. Toward the end, the book examines the potential of combination therapies to improve treatment outcomes in melanoma. The book is a valuable source for cancer researchers, medical oncologists, and clinicians. Key FeaturesProvides a comprehensive overview of melanoma, covering its fundamentals and introducing the latest diagnostics and treatment strategies.Investigates the transformative impact of artificial intelligence in melanoma diagnostics.Focuses on immunotherapeutic advancements against melanoma.Investigates the advancements in targeted therapies and nanomedicine.Explores the synergy of genomics and proteomics in a comprehensive multi-omics approach to melanoma treatment.

The book provides a comprehensive examination of pancreatic cancer, integrating global insights with an African-focused perspective. Understanding Pancreatic Cancer: Global Strategies and African Perspectives is structured into five parts, each addressing key aspects of the disease, from epidemiology to future innovations in care. Part I (Chapters 1 and 2) explores the global and African contexts, highlighting disparities in prevalence, diagnosis, and healthcare infrastructure. Part II (Chapter 3) delves into the biological and molecular mechanisms of pancreatic cancer, including genetic mutations and emerging therapeutic targets. Part III (Chapters 4 and 5) focuses on precision medicine and early detection, discussing advances such as artificial intelligence (AI) and biomarker-driven approaches. Part IV (Chapters 6-8) covers treatment strategies, from conventional therapies to novel interventions like immunotherapy and targeted treatments. Finally, Part V (Chapters 9-11) emphasizes the importance of advocacy, research, and policy reforms, outlining strategies for improving patient outcomes and shaping the future of pancreatic cancer care.By bridging scientific advancements with real-world challenges, this book serves as an essential resource for researchers, clinicians, and policymakers working to enhance pancreatic cancer diagnosis, treatment, and prevention—both in Africa and globally.Key FeaturesExamines pancreatic cancer worldwide, with a focus on Africa’s unique challenges and healthcare disparities.Explores molecular mechanisms, precision medicine, and AI-driven early detection.Covers surgery, chemotherapy, immunotherapy, and targeted therapies.Highlights research, healthcare policies, and strategies to improve patient care.

This book provides a comprehensive and integrated view of lung cancer, combining global evidence with African-specific perspectives. It examines the epidemiology, histological subtypes, and multifactorial causes of the disease, with in-depth coverage of genomic alterations, molecular signatures, and population-specific variations in Africa. The chapters explore the combined impact of environmental exposures, tobacco smoke, air pollution, asbestos, silica, radon, and indoor pollutants and infectious agents, including viruses, bacteria, and parasites, as drivers of lung carcinogenesis. The volume also addresses the role of the exposome, chronic infections, immune modulation, and the lung microbiome in shaping disease risk, treatment response, and survival outcomes. The book also presents the advances in molecular diagnostics, biomarker discovery, precision oncology, and AI-enabled healthcare innovations alongside the influence of social determinants such as poverty, education, cultural factors, and healthcare access. With a focus on prevention, early detection, and equitable access to care, the book highlights African-led research, public health policies, and system-level solutions to reduce disparities and improve outcomes.Key Features: Offers a comprehensive integration of global evidence with African-specific perspectives on lung cancerExplores epidemiology, histological subtypes, and multifactorial causes, including environmental and infectious driversHighlights genomic alterations, molecular signatures, and population-specific variations relevant to AfricaExamines the role of the exposome, chronic infections, immune modulation, and lung microbiome in carcinogenesis and outcomesProvides evidence-based recommendations for prevention, policy, and health system strengtheningThis book is intended for researchers, clinicians, policymakers, and students in cancer research, molecular biology, epidemiology, public health, and related biomedical and health sciences fields, globally, with particular relevance for those engaged in advancing lung cancer research and care in Africa and other resource-constrained settings.

This book highlights the use of artificial intelligence (AI), big data and precision oncology for medical decision making in cancer screening, diagnosis, prognosis and treatment.

This book highlights the use of artificial intelligence (AI), big data and precision oncology for medical decision making in cancer screening, diagnosis, prognosis and treatment.

This book analyses the ability of technological advancements to represent, enhance, and empower multidisciplinarity in the context of Society 5.0. and next generation medicine. New technologies allow patients to communicate with medical personnel anytime, anywhere and shape the terrain of healthcare ecosystem at an unprecedented rate. Five main trends become apparent in this process: Hybrid care models combining virtual and in-person services, digitization of healthcare specialties, increased Artificial intelligence (AI) adoption, health systems moving to the cloud and advanced precision medicine.In its chapters the book dissects the important roles for technologies in areas such as digital twinning, big data, Internet of Things, AI, cyber-physical systems, blockchain technology to lead the healthcare digitalization envisioned in Society 5.0. Throughout the book the authors discuss how to incorporate these new technologies legally, ethically, safely, and securely and in keeping with the highest standards of human rights. It also advocates for the need for careful oversight and mindful allocation of resources and energy for sustainable development.This book, written by experts in the field from academia and industry, will appeal to researchers, healthcare professionals, policy makers, teachers and students interested in the ways healthcare is reorganized based on digital transformation efforts and the rethinking of care, including technologies.

This book analyses the ability of technological advancements to represent, enhance, and empower multidisciplinarity in the context of Society 5.0. and next generation medicine. New technologies allow patients to communicate with medical personnel anytime, anywhere and shape the terrain of healthcare ecosystem at an unprecedented rate. Five main trends become apparent in this process: Hybrid care models combining virtual and in-person services, digitization of healthcare specialties, increased Artificial intelligence (AI) adoption, health systems moving to the cloud and advanced precision medicine.In its chapters the book dissects the important roles for technologies in areas such as digital twinning, big data, Internet of Things, AI, cyber-physical systems, blockchain technology to lead the healthcare digitalization envisioned in Society 5.0. Throughout the book the authors discuss how to incorporate these new technologies legally, ethically, safely, and securely and in keeping with the highest standards of human rights. It also advocates for the need for careful oversight and mindful allocation of resources and energy for sustainable development.This book, written by experts in the field from academia and industry, will appeal to researchers, healthcare professionals, policy makers, teachers and students interested in the ways healthcare is reorganized based on digital transformation efforts and the rethinking of care, including technologies.

This book addresses the pressing problem of drug resistance in the treatment of breast cancer.

This book addresses the pressing problem of drug resistance in the treatment of breast cancer. It provides a comprehensive understanding of the complex mechanisms underlying drug resistance and presents the latest advances in therapeutic approaches to overcome this enormous challenge.The book begins with an introduction to the biology of breast cancer, treatment modalities and the mechanisms of drug resistance. This includes the principles of drug resistance in targeted, immune-, endocrine and chemotherapy. In the following sections, the authors present innovative strategies to overcome drug resistance and new research directions, among others the role of the microbiome in drug resistance, molecular profiling of patients for personalized medical care, and new drug delivery systems. Finally, the book concludes with a discussion of the differences in the prevalence and treatment success of breast cancer between high- and low-income countries.  This book is an informative resource for students, researchers, and clinicians in the field of breast cancer research and oncology in general.

This book is an in-depth examination of the current state of the art and new advances in prostate cancer care and offers a fresh perspective with insights from Africa.At its core, the book tackles pivotal questions such as the mechanisms behind prostate cancer development, the significance of early detection, and how diagnostic advancements can lead to personalized treatment plans. It delves into genomic discoveries that are paving the way for targeted therapies and examines how immunotherapy is reshaping treatment paradigms. Furthermore, it explores surgical innovations and the role of radiopharmaceuticals in advancing prostate cancer management. The discussion extends to integrative care models that emphasize holistic patient well-being and strategies for enhancing survivorship. Unique about this book is that the authors provide insights from Africa into the prevalence and management of prostate cancer and place this in a global context. Aimed at healthcare professionals involved in oncology and prostate cancer research, including physicians, nurses and medical researchers, this book serves as an indispensable guide to the basic biological concepts of prostate cancer and its treatment in the clinic.