In this issue of Neuroimaging Clinics, guest editor Dr. Ana M. Franceschi brings her considerable expertise to the topic of Molecular Neuroimaging: Recent Advances in Clinical Practice. Top experts provide an introduction to PET/MRI, followed by up-to-date discussions of key topics such as radiopharmaceuticals in molecular neuroimaging: radiotracers in development; dementia and neurodegenerative disease: FTLD spectrum; neuro-oncology: intracranial metastatic disease; spine PET/MRI; theranostics in the CNS; and more.