New Developments in Redox Biology

Fundamental Roles in Health and Disease

Häftad, Engelska, 2025

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Beskrivning

New Developments in Redox Biology: Fundamental Roles in Health and Disease serves as a vital resource for understanding the profound impact of the redox system on human biology. In the book, readers are introduced to the intricate balance of oxidative stress, the delicate mechanisms of antioxidant defense, and their pivotal roles in cellular function. This book meticulously unpacks the connections between redox biology and the progression of health, aging, and disease, offering researchers and enthusiasts alike a window into these complex physiological processes.

Aside from illuminating oxidative dynamics, this book delves into emerging trends, therapeutic potential, and the integration of redox principles in developing medical interventions, highlighting its relevance in advancing human health.

Explores the fundamental role of redox biology in developmental processes and cellular homeostasis
Investigates the impact of oxidative stress on non-communicable diseases, including cancer, metabolic, and autoimmune disorders
Examines redox regulation in infectious diseases and host-pathogen interactions
Provides detailed insights into redox-related biomarkers and their diagnostic and therapeutic potential
Equips readers with cutting-edge knowledge on redox biology through multi-omics approaches

Produktinformation

Utgivningsdatum:2025-08-05
Mått:191 x 235 x 27 mm
Vikt:1 030 g
Format:Häftad
Språk:Engelska
Antal sidor:508
Förlag:Elsevier Science
ISBN:9780443438844

Utforska kategorier

Biologi inom Naturvetenskap och teknik

Mer om författaren

Dr. Asim K. Duttaroy is a professor at the Faculty of Medicine, University of Oslo, Oslo, Norway. His research programs focus on the roles of food components on growth and development, as well as in the prevention of diseases such as diabetes and cardiovascular disease. He is also investigating the roles of the antiplatelet and antihypertensive properties of fruits and vegetables. His discoveries of antithrombotic factors in tomatoes and kiwifruits are patented internationally, and three companies (Provexis Limited in the United Kingdom, IDIA AS in Norway, and Genimen Pharmacon in India) are working to commercialize these discoveries. He has published over 265 original contributions and reviews, 6 books, and several book chapters and editorials, and he is the Editor-in-Chief of the journal Food & Nutrition Research, as well as a guest editor of several journals such as Nutrients and Frontiers in Physiology. Dr. Atala Bihari Jena has a PhD in Biotechnology and over 7 years of experience in redox biology. He is an MK-Bhan Fellow at the National Center for Cell Science, Savitribai Phule Pune University, India and his main research expertise centres on oxidative stress, antioxidant enzymes, antioxidants, and the cellular redox system in health and disease.

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Innehållsförteckning

Section I: The redox theory of developmental biology1. The role of oxygen availability in embryonic development2. Balancing of oxidants via antioxidant enzymes in developmental biology3. Antioxidant-mediated O2 sensing epigenetic regulation4. Genetic basis of phenotypic plasticity in embryo under stress5. Cellular signalling cascade regulating embryonic development under oxidative stress6. Intra-cellular signalling cascade shielding against oxidative stress7. Stem cell homeostasis and differentiation under oxidative stress8. Multi-omics signature to oxidative response in cell growth & developmentSection II: Redox biology modulating non-communicable diseases9. Origin of cancer stem cells concerning hypoxia10. Redox-related biomarkers in tumorigenesis11. Metabolic disorder and its underlying redox biomarkers12. Redox regulation of autoimmune disorders13. Altered redox regulatory mechanisms in neurodegeneration14. Chronic inflammatory disorders and their redox control reaction15. Redox-related biomarkers in cardiovascular and immune-mediated inflammatory diseasesSection III: Impact of redox regulation on infectious biology16. Major redox biomarkers in host-pathogen interaction17. Redox control in the pathophysiology of zoonoses18. Antiviral therapeutics and their redox regulation19. The impact of hypoxia on intestinal invasion by bacterial pathogens20. Natural antioxidant therapeutics against microbial infection21. Redox profiling of pathogenic infection in poultry farms