New Developments in Redox Biology: Fundamental Roles in Health and Disease offers a comprehensive exploration of the influence of the redox system and the complex relationships between oxidative stress, biological development, health and disease. Divided into three sections, it explores the role of the redox system across developmental biology, non-communicable diseases, and infectious diseases. The first section includes chapters exploring oxygen availability in embryonic development, the influence of stress factors and intra-cellular signalling during embryogenesis, and how stem cells maintain homeostasis under oxidative stress. Section two considers topics such as the origin of cancer stem cells related to hypoxia, redox-related biomarkers in tumorigenesis and metabolic disorders, and the role of oxidation and reduction systems in autoimmune disorders and neurodegeneration. The final section focuses on redox regulation in infectious illness and includes chapters on redox biomarkers in host-pathogen interaction, the role of redox control in zoonotic diseases, and the significance of hypoxia on the ability of microbial pathogens to invade the gut. Antiviral drugs and the use of redox regulation in their mechanism of action is also explored. New Developments in Redox Biology: Fundamental Roles in Health and Disease offers a multidisciplinary approach to the topic, providing valuable insights to those seeking to expand their expertise in redox biology and its implications for human health and disease. In particular, researchers and advanced students working across molecular biology, cell biology, biochemistry, developmental biology and related fields will find this book useful.- Explores the fundamental role of redox biology in developmental processes and cellular homeostasis- Investigates the impact of oxidative stress on non-communicable diseases, including cancer, metabolic, and autoimmune disorders- Examines redox regulation in infectious diseases and host-pathogen interactions- Provides detailed insights into redox-related biomarkers and their diagnostic and therapeutic potential- Equips readers with cutting-edge knowledge on redox biology through multi-omics approaches
