Market-Driven Development of Inhaled Drug Products

Translating Research into Marketable Drug Products

Häftad, Engelska, 2027

2 034 kr

Kommande

Beskrivning

Market-Driven Development of Inhaled Drug Products: Translating Research into Marketable Drug Products addresses the rapidly evolving field of pulmonary drug delivery, which has gained prominence for treating respiratory diseases and systemic therapies, including COVID-19. Despite its promise, inhaled drug development faces complex challenges such as respiratory physiology constraints, limited excipient approvals, and the necessity for drug-device combination products. This reference fills a critical gap by translating cutting-edge research into practical product development strategies. The content spans foundational topics including inhalation dosimetry, pulmonary pharmacokinetics, and safety studies, progressing to drug discovery, device influence, preclinical models, and regulatory frameworks. It further covers excipient selection, patient compliance, device engineering innovations including 3D printing, and packaging considerations. Contributions from leading experts worldwide provide a multidisciplinary perspective essential for navigating the complexities of inhaled drug development. Market-Driven Development of Inhaled Drug Products: Translating Research into Marketable Drug Products benefits pharmaceutical scientists and engineers by offering an integrated approach to inhaled therapy development. It supports improving product development cycles, regulatory submissions, and clinical trial designs while addressing patient adherence challenges. This reference is an indispensable resource for advancing inhaled therapeutics from concept to market.

Addresses the full inhaled drug product development lifecycle from research to market
Integrates physiology, device engineering, and patient compliance considerations
Provides comprehensive regulatory and safety perspectives for inhaled therapies
Includes case studies and recent advances for practical application
Emphasizes translational approaches bridging preclinical and clinical development

Produktinformation

Utgivningsdatum:2027-03-01
Mått:191 x 235 x undefined mm
Vikt:450 g
Format:Häftad
Språk:Engelska
Antal sidor:400
Förlag:Elsevier Science
ISBN:9780443444012

Utforska kategorier

Tillverkningsindustri inom Ekonomi och Ledarskap
Farmakologi inom Medicin

Mer om författaren

Dr. Vivek Gupta received his Ph.D. in pharmaceutical sciences from Texas Tech University Health Sciences Center, Amarillo, TX. He is currently an assistant professor of industrial pharmacy and pharmaceutics at St. John’s University in New York City. He has more than 10 years of experience in formulation design for novel drug delivery systems for non-invasive delivery of therapeutics, pharmacokinetic and pharmacodynamic characterization of delivery systems for enhanced lung accumulation and bioavailability. Dr. Vivek Gupta’s current research is focused on drug discovery and delivery of novel therapeutic agents for rare disorders of the cardiopulmonary system including pulmonary fibrosis, pulmonary hypertension, and mesothelioma, a rare form of lung cancer associated with asbestos exposure. Dr. Gupta has published 45 journal articles and book chapters in his research field.

Innehållsförteckning

1. IntroductionPart I – Foundations of Inhaled Drug Product Development2. Dosimetry in Inhaled Product Development3. Inhalation Safety Studies4. Pulmonary Drug Disposition5. Pharmacokinetic-Pharmacodynamic Relationships in the LungPart II – Development of Inhaled Products6. Drug Discovery and Drug Development7. Influence of the Inhalation Delivery Device8. Pre-Clinical Studies9. Uses and Limitations of Animal Models10. Regulatory AspectsPart III – Practical Inhaled Drug Product Development11. Excipient Selection12. Excipient Safety and Toxicological Profile & Functional Excipients13. Medicine Compliance14. Device Development15. Packaging and DistributionPart IV – Conclusions16. The Current Status of Inhaled Drug Product Development