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    1. Medicin
    2. Medicin: icke kliniska discipliner
    3. Fysiologi

    ETHNOPHARMACOLOGICAL STRATEGIE

    Evidence-Based Molecular Mechanisms and Clinical Outcomes

    AvDebidas Ghosh,Krishnendu Adhikary

    Häftad, Engelska, 2027

    1 773 kr

    Kommande

    Beskrivning

    Ethnopharmacological Strategies for Diabetes-Associated Reproductive Co-morbidities: Evidence-Based Molecular Mechanisms and Clinical Outcomes is a comprehensive, interdisciplinary reference addressing the complex link between diabetes mellitus and infertility in both men and women. This edited volume synthesizes molecular insights into diabetes-induced reproductive dysfunction-such as oxidative stress, inflammation, endocrine disruption, and tissue damage-with evidence-based evaluations of medicinal plants and their bioactive phytochemicals. It bridges laboratory research and clinical trials to highlight how plant-derived compounds can regulate glycemic control, restore hormonal balance, reduce oxidative damage, and improve gametogenesis. Targeting clinicians, researchers, and postgraduate students in biomedical and pharmaceutical sciences, the book offers detailed therapeutic profiles, safety assessments, and translational applications. By consolidating fragmented knowledge, it empowers healthcare professionals and scientists to develop integrative, cost-effective strategies for managing diabetes-related infertility.

    • Integrates a molecular-to-clinical framework connecting biochemical and molecular mechanisms of diabetes-induced infertility with clinical evidence to understand the underlying causes and therapeutic rationale
    • Includes Male and Female Reproductive Health addresses infertility in both genders, covering hormonal regulation, gametogenesis, oxidative stress, and inflammation, ensuring a holistic understanding of diabetes-associated reproductive issues
    • Offers actionable clinical guidance, diagnostic considerations, combination therapy strategies, and a roadmap for future research to facilitate real-world application and innovation

    Produktinformation

    • Utgivningsdatum:2027-04-01
    • Mått:191 x 235 x undefined mm
    • Format:Häftad
    • Språk:Engelska
    • Antal sidor:240
    • Förlag:Elsevier Science
    • ISBN:9780443490903

    Utforska kategorier

    • Fysiologi inom Medicin
    • Endokrinologi inom Medicin

    Mer om författaren

    Prof. Debidas Ghosh is a distinguished academician and researcher specializing in Nutrigenomics, Molecular Medicine, Public Health, and Endocrinology. With over three decades of experience, his expertise spans physiology, environmental science, and biomedical research. He has led numerous funded projects focusing on molecular mechanisms underlying health and disease, including endocrine system regulation and metabolic disorders. Prof. Ghosh’s work integrates nutritional genomics with endocrine function to advance understanding of disease prevention and management. He is also skilled in mentoring research in endocrinology, molecular biology, and public health, contributing significantly to scientific innovation and education in these fields. He has published extensively, with 164 international and 31 national journal articles, and authored four reference books. Honors include the P.B. Sen Gold Medal, UGC Research Award, Indo-Tunisia Bilateral Fellowship, and multiple "Siksha Ratna" awards. he has mentored over 40 Ph.D. scholars and holds two registered patents. he remains a leading figure in biomedical research. Dr. Krishnendu Adhikary is Assistant Professor and Head of the Department of Medical Lab Technology at Paramedical College, Durgapur, West Bengal, India. He holds an M.Sc. in Human Physiology with a specialization in Neurophysiology from the University of Calcutta. Dr. Adhikary’s research focuses on regenerative medicine, particularly diabetic wound healing and tissue regeneration. He has published 50 research papers, in peer-reviewed international journals, authored 10 book chapters, and holds 9 Indian and 1 UK design patents, with additional patents pending. He has edited six books with major academic publishers. He is the recipient of the Junior Scientist and Young Scientist Awards from the National Environmental Science Academy, and has earned numerous presentation prizes at national and international conferences. With nine years of teaching experience, Dr. Adhikary is skilled in Human Physiology, Biochemistry, Histopathology, Cytology, Molecular Medicine, Immunology, Endocrinology, Neurophysiology, and Ocular Physiology, mentoring over 10 student projects and dissertations. Dr. Riya Sarkar, Assistant Professor in the Department of Medical Laboratory Technology at Dr. B. C. Roy Academy of Professional Courses, Durgapur, West Bengal. Received B.Sc. in Botany and M.Sc. in Bio-Medical Laboratory Science and Management. Awarded the University Gold Medal in 2017 for securing first rank in postgraduate program. Ph.D. at Vidyasagar University. Her research contributions include several publications journals, , and contributed to 10 International book chapters. Dr. Sarkar has reviewed many manuscripts for Elsevier journals. In addition to academic and research work, she has been appointed as an external paper setter and examiner for BMLT examinations of multiple institutions. Teaching areas of Dr. Sarkar are hematology, histology, histopathology, pathology, serology, endocrinology, blood banking, biochemistry, and molecular biology. With over seven years of research experience, her work primarily focuses on diabetes and the therapeutic potential of phytomolecules in managing diabetes-induced male infertility Dr. Rajkumar Maiti, Associate Professor of Physiology at Bankura Christian College, West Bengal, India. He holds a Ph.D. from Vidyasagar University, where he also earned his B.Sc., M.Sc. in Physiology, and B.Ed. His expertise spans Physiology, Human Biology, and Phytochemistry, with research focused on herbal hypoglycemic drug development, oxidative stress, and translational integration of traditional and modern medicine. He has published over 63 peer-reviewed articles and two book chapters. He has received multiple honors, including the Prof. B. B. Sarkar Memorial Oration and several awards from the National Environmental Science Academy. He holds an Indian patent for a special bed design aiding aged and incontinent patients. Active in professional societies, he contributes to curriculum development and research governance, serving as Convenor and member of Undergraduate Boards of Studies at several universities. Dr. Maiti is dedicated to advancing physiological science and herbal medicine through education and research leadership.

    Innehållsförteckning

    • 1. Global Epidemiology and Socioeconomic Burden of Diabetes-Associated Infertility2. Pathophysiological Mechanisms Linking Diabetes Mellitus to Reproductive Dysfunction3. Oxidative Stress and Mitochondrial Bioenergetic Failure in Reproductive Cells4. Chronic Inflammation and Cytokine-Mediated Reproductive Impairment5. Advanced Glycation End Products, RAGE Signaling, and Reproductive Tissue Damage6. Endocrine Dysregulation in Male and Female Diabetic Infertility7. Male Reproductive Alterations: Sperm Dysfunction, DNA Damage, and Seminal Oxidative Stress8. Female Reproductive Alterations: Ovarian Reserve, Oocyte Quality, and Luteal Insufficiency9. Endometrial Receptivity and Embryo Implantation Failure in Diabetes Mellitus10. Comprehensive Inventory of Medicinal Plants with Dual Antidiabetic and Fertility-Promoting Activities11. Antioxidant-Rich Phytochemicals Targeting Oxidative Stress in Reproductive Tissues12. Phytochemicals Modulating Hormonal Profiles and Insulin Sensitivity13. Anti-Inflammatory Phytoconstituents in the Restoration of Reproductive Health14. Experimental Evidence from Animal Models of Diabetes-Related Infertility15. Human Clinical Trials on Medicinal Plants for Diabetes-Induced Infertility16. Synergistic and Polyherbal Formulations for Fertility Restoration in Diabetes17. Pharmacokinetic and Pharmacodynamic Interactions between Medicinal Plants and Conventional Therapies18. From Plant to Product: Nutraceutical Development for Diabetes-Induced Infertility19. Future Research Priorities and Translational Pathways in Botanical Therapeutics20. Policy, Regulation, and Ethical Dimensions of Medicinal Plant Use in Reproductive Medicine