Spinal Cord Injury

"Providing the latest information on all aspects of spinal cord injury, this volume supplants a 1992 work published in the Handbook of Clinical Neurology series titled Spinal Cord Trauma. Bridging the gap between bench and bedside, coverage encompasses diagnosis and prognosis; medical, surgical, and rehabilitative management of acute spinal cord injury; therapies for chronic spinal cord injury; and preclinical research." --Reference and Research Book News, October 2013

• SECTION 1 Developmental and Anatomical Perspectives1. Development and maturation of the spinal cord: implications of molecular and genetic defects; 2. Anatomy and biomechanics of the spinal column and cordSECTION 2 Diagnosis and Prognosis3. Clinical diagnosis and prognosis following spinal cord injury; 4. Clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury; 5. Concepts of aging with paralysis: implications for recovery and treatment; 6. Advanced MRI strategies for assessing spinal cord injurySECTION 3 Acute Spinal Cord Injury: Medical, Surgical and Rehabilitative Management7. Advances in the management of spinal cord and spinal column injuries; 8. Spinal cord injuries in children and adolescents; 9. The changing landscape of spinal cord injury; 10. Surgical treatments to restore function control in spinal cord injury; 11. Advances in the rehabilitation management of acute spinal cord injury; 12. Spasticity; 13. Disordered cardiovascular control after spinal cord injury; 14. New concepts in the prevention of pressure sores; 15. Functional electrical stimulation for bladder, bowel and sexual function; 16. Evidence based therapy for recovery of function after spinal cord injury; 17. Functional electrical stimulation: restoration of respiratory function; 18. Spinal cord stimulation: therapeutic benefits and movement generation after spinal cord Injury; 19. Promoting optimal functioning in spinal cord injury: the role of rehabilitation psychologySECTION 4 Chronic Spinal Cord Injury – The Changing Perspective of Neurorestorative Rehabilitation, Activity-Based and Surgical Restoration Therapies20. The changing field of rehabilitation: optimizing spontaneous regeneration and functional recovery; 21. The longitudinal spinal cord injury: lessons from intra spinal plexus, cauda equina and medullary conus lesions; 22. Post-traumatic syringomyelia; 23. Post-traumatic deformity: prevention and management SECTION 5 Preclinical Research - Bridging the Gap Between Bench and Bedside24. Spinal cord injury clinical trials: translational process, review of past and proposed acute trials with reference to recommended trial guidelines; 25. Translating preclinical approaches into human application; 26. Translational spinal cord injury research: preclinical guidelines and challenges; 27. Brain-machine interfaces and transcranial stimulation: future implications for directing functional movement and improving function after spinal injury in humans; 28. Approaches to repairing the damaged spinal cord: overview; 29. Limiting spinal cord injury by pharmacological intervention; 30. Harmful and beneficial effects of inflammation after spinal cord injury: potential therapeutic implications; 31. Defeating inhibition of regeneration by scar and myelin components; 32. Realising the maximum potential of Schwann cells to promote recovery from spinal cord injury; 33. Repair of CNS lesions by transplantation of olfactory ensheathing cells; 34. Cell transplantation: stem cells and precursor cells; 35. Gene therapy, neurotrophic factors and spinal cord regeneration; 36. Scaffolds to promote spinal cord regeneration; 37. Molecular target discovery for neural repair in the functional genomics era; 38. Combination therapies