Rita Cornelis, Department of Analytical Chemistry, Ghent University, The Netherlands.

"...should definitely be available in the reference library of every university or organization where speciation studies are carried out."  (Applied Organometallic Chemistry, November 2007)

• List of Contributors viiPreface ixAcknowledgments xiTechnical Abbreviations and Acronyms xiii1 Introduction 12 Element by Element Review 52.1 Introduction 52.2 Speciation of Aluminum 72.2.1 Speciation of Aluminum in the Environment 72.2.2 Speciation of Aluminum in Food: Sources, Including Potable Water 202.2.3 Speciation of Aluminum in Clinical Aspects (Health & Disease) 272.2.4 Speciation of Aluminum in Occupational Health 402.3 Speciation of Antimony 472.4 Speciation of Arsenic 692.4.1 Arsenic and Arsenic Species in Environment and Human Nutrition 692.4.2 Arsenic Speciation in Human Tissues 862.5 Speciation of Cadmium 942.5.1 Speciation of Cadmium in the Environment and Food 942.5.2 Speciation of Cadmium in Health and Disease 1072.6 Speciation of Chromium 1202.6.1 Speciation of Chromium in Environment and Food 1202.6.2 Speciation of Chromium in Occupational Exposure and Clinical Aspects 1362.7 Speciation of Cobalt 1582.8 Speciation of Copper 1742.8.1 Speciation of Copper in the Environment 1742.8.2 Speciation of Copper in Clinical and Occupational Aspects 1872.9 Speciation of Iron 2002.9.1 Speciation of Iron in the Environment 2002.9.2 Iron Speciation in Biomedicine 2182.10 Speciation of Lead 2392.10.1 Environmental Speciation of Lead 2392.10.2 Speciation of Lead in Food and Wine 2472.10.3 Speciation of Lead in Occupational Exposure and Clinical Health Aspects  2522.11 Speciation of Manganese 2772.12 Speciation of Mercury: Environment, Food, Clinical, and Occupational Health 2812.13 Speciation of Molybdenum 3052.14 Speciation of Nickel 3102.15 Speciation of Platinum, Palladium, Gold and Rhodium 3272.15.1 Importance of Platinum Group Elements and Gold Speciation in the Environment and Medicine 3272.15.2 Speciation of Platinum Group Elements and Gold in Occupational Exposure 3382.16 Speciation of Selenium 3462.17 Speciation of Silicon 3662.18 Speciation of Sulfur 3782.19 Speciation of Thallium 4082.20 Speciation of Tin 4222.21 Speciation of Vanadium 4642.22 Speciation of Zinc 4882.23 Speciation of Actinides 5092.24 Speciation of Halogen Compounds 5642.25 Volatile Metal Compounds of Biogenic Origin 5982.26 Metal Complexes of Humic Substances 6212.27 Selected Examples of Important Metal–Protein Species 6383 Modeling of Elemental Species 6513.1 Thermodynamic Modeling of Trace Element Partitioning in the Environment: New Concepts and Outlook 6513.2 Modeling in Nutrition The Metabolism of Selenium, Copper, Zinc and Calcium Using Stable Isotopes in Humans 6903.3 Modeling of Trace Element Species in Health and Disease 7133.3.1 Pharmacokinetic Approach and Mathematical Modeling 7153.3.2 Modeling of Biological Ligand Binding 7284 Speciation and the Emerging Legislation 737Index 745

Rita Cornelis, Department of Analytical Chemistry, Ghent University, The Netherlands.

"...should definitely be available in the reference library of every university or organization where speciation studies are carried out."  (Applied Organometallic Chemistry, November 2007)

• List of Contributors viiPreface ixAcknowledgments xiTechnical Abbreviations and Acronyms xiii1 Introduction 12 Element by Element Review 52.1 Introduction 52.2 Speciation of Aluminum 72.2.1 Speciation of Aluminum in the Environment 72.2.2 Speciation of Aluminum in Food: Sources, Including Potable Water 202.2.3 Speciation of Aluminum in Clinical Aspects (Health & Disease) 272.2.4 Speciation of Aluminum in Occupational Health 402.3 Speciation of Antimony 472.4 Speciation of Arsenic 692.4.1 Arsenic and Arsenic Species in Environment and Human Nutrition 692.4.2 Arsenic Speciation in Human Tissues 862.5 Speciation of Cadmium 942.5.1 Speciation of Cadmium in the Environment and Food 942.5.2 Speciation of Cadmium in Health and Disease 1072.6 Speciation of Chromium 1202.6.1 Speciation of Chromium in Environment and Food 1202.6.2 Speciation of Chromium in Occupational Exposure and Clinical Aspects 1362.7 Speciation of Cobalt 1582.8 Speciation of Copper 1742.8.1 Speciation of Copper in the Environment 1742.8.2 Speciation of Copper in Clinical and Occupational Aspects 1872.9 Speciation of Iron 2002.9.1 Speciation of Iron in the Environment 2002.9.2 Iron Speciation in Biomedicine 2182.10 Speciation of Lead 2392.10.1 Environmental Speciation of Lead 2392.10.2 Speciation of Lead in Food and Wine 2472.10.3 Speciation of Lead in Occupational Exposure and Clinical Health Aspects  2522.11 Speciation of Manganese 2772.12 Speciation of Mercury: Environment, Food, Clinical, and Occupational Health 2812.13 Speciation of Molybdenum 3052.14 Speciation of Nickel 3102.15 Speciation of Platinum, Palladium, Gold and Rhodium 3272.15.1 Importance of Platinum Group Elements and Gold Speciation in the Environment and Medicine 3272.15.2 Speciation of Platinum Group Elements and Gold in Occupational Exposure 3382.16 Speciation of Selenium 3462.17 Speciation of Silicon 3662.18 Speciation of Sulfur 3782.19 Speciation of Thallium 4082.20 Speciation of Tin 4222.21 Speciation of Vanadium 4642.22 Speciation of Zinc 4882.23 Speciation of Actinides 5092.24 Speciation of Halogen Compounds 5642.25 Volatile Metal Compounds of Biogenic Origin 5982.26 Metal Complexes of Humic Substances 6212.27 Selected Examples of Important Metal–Protein Species 6383 Modeling of Elemental Species 6513.1 Thermodynamic Modeling of Trace Element Partitioning in the Environment: New Concepts and Outlook 6513.2 Modeling in Nutrition The Metabolism of Selenium, Copper, Zinc and Calcium Using Stable Isotopes in Humans 6903.3 Modeling of Trace Element Species in Health and Disease 7133.3.1 Pharmacokinetic Approach and Mathematical Modeling 7153.3.2 Modeling of Biological Ligand Binding 7284 Speciation and the Emerging Legislation 737Index 745

Rita Cornelis, Department of Analytical Chemistry, Ghent University, The Netherlands.

"...should definitely be available in the reference library of every university or organization where speciation studies are carried out."  (Applied Organometallic Chemistry, November 2007)

• List of Contributors viiPreface ixAcknowledgments xiTechnical Abbreviations and Acronyms xiii1 Introduction 12 Element by Element Review 52.1 Introduction 52.2 Speciation of Aluminum 72.2.1 Speciation of Aluminum in the Environment 72.2.2 Speciation of Aluminum in Food: Sources, Including Potable Water 202.2.3 Speciation of Aluminum in Clinical Aspects (Health & Disease) 272.2.4 Speciation of Aluminum in Occupational Health 402.3 Speciation of Antimony 472.4 Speciation of Arsenic 692.4.1 Arsenic and Arsenic Species in Environment and Human Nutrition 692.4.2 Arsenic Speciation in Human Tissues 862.5 Speciation of Cadmium 942.5.1 Speciation of Cadmium in the Environment and Food 942.5.2 Speciation of Cadmium in Health and Disease 1072.6 Speciation of Chromium 1202.6.1 Speciation of Chromium in Environment and Food 1202.6.2 Speciation of Chromium in Occupational Exposure and Clinical Aspects 1362.7 Speciation of Cobalt 1582.8 Speciation of Copper 1742.8.1 Speciation of Copper in the Environment 1742.8.2 Speciation of Copper in Clinical and Occupational Aspects 1872.9 Speciation of Iron 2002.9.1 Speciation of Iron in the Environment 2002.9.2 Iron Speciation in Biomedicine 2182.10 Speciation of Lead 2392.10.1 Environmental Speciation of Lead 2392.10.2 Speciation of Lead in Food and Wine 2472.10.3 Speciation of Lead in Occupational Exposure and Clinical Health Aspects  2522.11 Speciation of Manganese 2772.12 Speciation of Mercury: Environment, Food, Clinical, and Occupational Health 2812.13 Speciation of Molybdenum 3052.14 Speciation of Nickel 3102.15 Speciation of Platinum, Palladium, Gold and Rhodium 3272.15.1 Importance of Platinum Group Elements and Gold Speciation in the Environment and Medicine 3272.15.2 Speciation of Platinum Group Elements and Gold in Occupational Exposure 3382.16 Speciation of Selenium 3462.17 Speciation of Silicon 3662.18 Speciation of Sulfur 3782.19 Speciation of Thallium 4082.20 Speciation of Tin 4222.21 Speciation of Vanadium 4642.22 Speciation of Zinc 4882.23 Speciation of Actinides 5092.24 Speciation of Halogen Compounds 5642.25 Volatile Metal Compounds of Biogenic Origin 5982.26 Metal Complexes of Humic Substances 6212.27 Selected Examples of Important Metal–Protein Species 6383 Modeling of Elemental Species 6513.1 Thermodynamic Modeling of Trace Element Partitioning in the Environment: New Concepts and Outlook 6513.2 Modeling in Nutrition The Metabolism of Selenium, Copper, Zinc and Calcium Using Stable Isotopes in Humans 6903.3 Modeling of Trace Element Species in Health and Disease 7133.3.1 Pharmacokinetic Approach and Mathematical Modeling 7153.3.2 Modeling of Biological Ligand Binding 7284 Speciation and the Emerging Legislation 737Index 745