"From beginning to end this is a book of highest quality in content and readability. Moreover, it defines many areas for future research in mammalian embryology." Science

• Preface; Contributors; Part I. Cellular Aspects: 1. Potency, lineage, and allocation in preimplantation mouse embryos Roger A. Pedersen; 2. Time and space in the mouse early embryo: a cell biological approach to cell diversification Martin H. Johnson and Bernard Maro; 3. Comparative aspects of embryo manipulation in mammals Virginia E. Papaioannou and Karl M. Elbert; 4. Development of extraembryonic cell lineages in the mouse embryo Janet Rossant; 5. Analysis of tissue fate and prospective potency in the egg cylinder Rosa Beddington; Part II. Molecular and Biochemical Aspects: 6. Regulation of gene expression during mammalian spermatogenesis Norman B. Hecht; 7. Molecular aspects of mammalian oocyte growth and maturation Richard M. Schultz; 8. Utilization of genetic information in the preimplantation mouse embryo Gilbert A. Schultz; 9. Metabolic aspects of the physiology of the preimplantation embryo Peter L. Kaye; 10. Role of cell surface molecules in early mammalian development Jean Richa and Davor Solter; 11. Cell-lineage-specific gene expression in development Eileen D. Adamson; 12. X-chromosome regulation in oogenesis and early mammalian development Verne M. Chapman; Part III. Toward a Genetic Understanding of Development: 13. Evidences and consequences of differences between maternal and paternal genomes during embryogenesis in the mouse M. Azim H. Surani; 14. Mutations and chromosomal abnormalities: How are they useful for studying genetic control of early mammalian development? Terry Magnuson; 15. Production of permanent cell lines from early embryos and their use in studying developmental problems Elizabeth J. Robertson and Allan Bradley; 16. Integration and expression of genes introduced into mouse embryos Erwin F. Wagner and Colin L. Stewart; Index.