Eduardo D. Bruera, MD, is Professor and Head of Palliative Care and Rehabilitation Medicine, and the F. T. McGraw Chair in the Treatment of Cancer, at the University of Texas M. D. Anderson Cancer Center, Houston, Texas. Russell K. Portenoy, MD, is Chairman of the Department of Pain Medicine and Palliative Care and holds the Gerald J. and Dorothy R. Friedman Chair in Pain and Palliative Care at Beth Israel Medical Center, New York. He is also chief medical officer of Continuum Hospice Care's Jacob Perlow Hospice, as well as Professor of Neurology and Anesthesiology at the Albert Einstein College of Medicine, Bronx, New York.

'The list of editors and contributing authors reads like a who's who in the field of cancer-pain management … This comprehensive yet practical book contains all the information needed to provide appropriate interventions to relieve pain in patients who have cancer, while also dispelling the myths and concerns that have contributed to the reluctance of physicians to provide such care. This book should be in the library of every physician who comes into contact with patients with pain. It is truly superb.' New England Journal of Medicine

• Part I. Mechanisms and Epidemiology: 1. Nociception: basic principles Rie Suzuki, Shafaq Sikandar and Anthony H. Dickenson; 2. Pathophysiology of malignant bone pain Juan Miguel Jimenez-Andrade, Monica Herrera and Patrick Mantyh; Part II. Epidemiology and Syndromes: 3. Cancer pain epidemiology Irene J. Higginson and Fliss Murtagh; 4. Cancer pain syndromes Mervyn Koh and Russell K. Portenoy; Part III. Assessment: 5. The assessment of cancer pain: measurement strategy Karen O. Anderson; 6. Multidimensional assessment: pain and palliative care Norma O'Leary, Carol Stone and Peter G. Lawlor; 7. Evaluating pain for children with cancer Patricia A. McGrath and Eric J. Crawford; 8. Pain syndromes in cancer survivors Rosemary C. Polomano, Michael Ashburn and John T. Farrar; Part IV. Pharmacological Treatment: 9. Pharmacology of analgesia: basic principles Charles E. Inturrisi; 10. Pharmacogenetic considerations in the treatment of cancer pain Pål Klepstad; 11. Pharmacology of opioid analgesia: clinical principles Carla Ripamonti and Claudia Bareggi; 12. Opioid side effects and management Maxine De La Cruz and Eduardo Bruera; 13. Antipyretic analgesics Burkhard Hinz and Kay Brune; 14. Adjuvant analgesic drugs Russell K. Portenoy and Mervyn Koh; 15. Neuraxial analgesia L. Holford and Michael Cousins; Part V. Other Interventional Strategies: 16. Neural blockade for cancer pain Rebecca Chan and Oscar de Leon-Cassasola; 17. Neurosurgical treatment of cancer pain Robert W. Hurley and Fred A. Lenz; Part VI. Rehabilitation and Psychological Interventions: 18. Psychological interventions for cancer pain Francis J. Keefe, Amy P. Abernethy, Jane L. Wheeler and Tamara J. Somers; 19. Rehabilitation medicine interventions Jack B. Fu, Ki Y. Shin and Theresa A. Gillis; Part VII. The Role of Antineoplastic Therapies in Pain Control: 20. Palliative radiotherapy Alysa Fairchild and Edward Chow; 21. Palliative systemic antineoplastic therapy Michael J. Fisch; 22. Cancer pain management in the chemically dependent patient Steven D. Passik, Lara K. Dhingra and Kenneth L. Kirsh; Part VIII: Pain in Special Populations: 23. Cancer pain in children Richard Hain; 24. Managing cancer pain in the elderly Marvin Omar Delgado-Guay and David Wollner; Part IX. Difficult Pain Problems: 25. Cancer pain and depression William S. Breitbart, Wendy G. Lichtenthal, Hayley Pessin and Gloria Lee; 26. Neuropathic pain Ricardo A. Cruciani, E. Alessandra Strada and Helena Knotkova; 27. Breakthrough pain Sebastiano Mercadante; 28. Bone pain Badi El Osta and Eduardo Bruera; Part X. Systems of Care: 29. Integrating cancer pain management into hospice practice and institution-based palliative care programs Sandra P. Gomez and Paul W. Walker; 30. Pain in medical illness: ethical foundations Pauline Lesage and Russell K. Portenoy; 31. Understanding clinical trials in pain research John T. Farrar and Scott D. Halpern; 32. Legal and regulatory aspects of opioid treatment: the United States experience June L. Dahl; 33. Role of family caregivers in cancer pain management Myra Glajchen; 34. Cancer pain and palliative care in the developing world Roberto Wenk, Daniela Mosoiu and M. R. Rajagopal.