Scott Stroup is Professor of Psychiatry at the University of North Carolina, Chapel Hill, USA. He was co-Principal Investigator of the CATIE Schizophrenia Study. Jeffrey A. Lieberman is Chairman, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, Director, New York State Psychiatric Institute and Director, Lieber Center for Schizophrenia Research Psychiatrist-in-Chief at New York Presbyterian Hospital and Columbia University Medical Center, New York, USA.

'… important and timely …' Doody's

• List of contributors; Acknowledgements; Introduction; 1. Study design and protocol development process T. Scott Stroup, Joseph P. McEvoy and Jeffrey A. Lieberman; 2. Statistical considerations Sonia M. Davis, Gary G. Koch, Robert A. Rosenheck and Vicki G. Davis; 3. Effectiveness and efficacy: staying on treatment and symptom reduction Joseph P. McEvoy, T. Scott Stroup and Jeffrey A. Lieberman; 4. Cost-effectiveness and cost-benefit analysis Robert A. Rosenheck and Douglas L. Leslie; 5. Psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study Marvin S. Swartz; 6. Neurocognition Richard S. E. Keefe; 7. Vocational outcomes Sandra G. Resnick and Robert A. Rosenheck; 8. Family outcomes Deborah A. Perlick, Richard Kaczynski and Robert A. Rosenheck; 9. Extrapyramidal side effects Stanley N. Caroff, Del D. Miller and Robert A. Rosenheck; 10. Metabolic side effects and risk of cardiovascular disease Jonathan M. Meyer, Donald C. Goff and Joseph P. McEvoy; 11. Substance use in persons with schizophrenia: incidence, baseline correlates, and effects on outcome Fred Reimherr, Marvin S. Swartz and John L. Olsen; 12. Violence in schizophrenia: prevalence, correlates, and treatment effectiveness Jeffrey Swanson and Richard Van Dorn; 13. Genetic investigations in the CATIE sample James J. Crowley and Patrick F. Sullivan; 14. Human subjects considerations T. Scott Stroup and Paul Appelbaum; 15. Population pharmacokinetics of antipsychotics Kristin L. Bigos, Robert R. Bies, Stephen R. Marder and Bruce G. Pollock; 16. Implications for research design and study implementation T. Scott Stroup and Jeffrey A. Lieberman; 17. Conclusion and implications for practice and policy Robert A. Rosenheck, T. Scott Stroup and Jeffrey A. Lieberman.

Scott Stroup is Professor of Psychiatry at the University of North Carolina, Chapel Hill, USA. He was co-Principal Investigator of the CATIE Schizophrenia Study. Jeffrey A. Lieberman is Chairman, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, Director, New York State Psychiatric Institute and Director, Lieber Center for Schizophrenia Research Psychiatrist-in-Chief at New York Presbyterian Hospital and Columbia University Medical Center, New York, USA.

'… important and timely …' Doody's

• List of contributors; Acknowledgements; Introduction; 1. Study design and protocol development process T. Scott Stroup, Joseph P. McEvoy and Jeffrey A. Lieberman; 2. Statistical considerations Sonia M. Davis, Gary G. Koch, Robert A. Rosenheck and Vicki G. Davis; 3. Effectiveness and efficacy: staying on treatment and symptom reduction Joseph P. McEvoy, T. Scott Stroup and Jeffrey A. Lieberman; 4. Cost-effectiveness and cost-benefit analysis Robert A. Rosenheck and Douglas L. Leslie; 5. Psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study Marvin S. Swartz; 6. Neurocognition Richard S. E. Keefe; 7. Vocational outcomes Sandra G. Resnick and Robert A. Rosenheck; 8. Family outcomes Deborah A. Perlick, Richard Kaczynski and Robert A. Rosenheck; 9. Extrapyramidal side effects Stanley N. Caroff, Del D. Miller and Robert A. Rosenheck; 10. Metabolic side effects and risk of cardiovascular disease Jonathan M. Meyer, Donald C. Goff and Joseph P. McEvoy; 11. Substance use in persons with schizophrenia: incidence, baseline correlates, and effects on outcome Fred Reimherr, Marvin S. Swartz and John L. Olsen; 12. Violence in schizophrenia: prevalence, correlates, and treatment effectiveness Jeffrey Swanson and Richard Van Dorn; 13. Genetic investigations in the CATIE sample James J. Crowley and Patrick F. Sullivan; 14. Human subjects considerations T. Scott Stroup and Paul Appelbaum; 15. Population pharmacokinetics of antipsychotics Kristin L. Bigos, Robert R. Bies, Stephen R. Marder and Bruce G. Pollock; 16. Implications for research design and study implementation T. Scott Stroup and Jeffrey A. Lieberman; 17. Conclusion and implications for practice and policy Robert A. Rosenheck, T. Scott Stroup and Jeffrey A. Lieberman.

Scott Stroup is Professor of Psychiatry at the University of North Carolina, Chapel Hill, USA. He was co-Principal Investigator of the CATIE Schizophrenia Study. Jeffrey A. Lieberman is Chairman, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, Director, New York State Psychiatric Institute and Director, Lieber Center for Schizophrenia Research Psychiatrist-in-Chief at New York Presbyterian Hospital and Columbia University Medical Center, New York, USA.

'… important and timely …' Doody's

• List of contributors; Acknowledgements; Introduction; 1. Study design and protocol development process T. Scott Stroup, Joseph P. McEvoy and Jeffrey A. Lieberman; 2. Statistical considerations Sonia M. Davis, Gary G. Koch, Robert A. Rosenheck and Vicki G. Davis; 3. Effectiveness and efficacy: staying on treatment and symptom reduction Joseph P. McEvoy, T. Scott Stroup and Jeffrey A. Lieberman; 4. Cost-effectiveness and cost-benefit analysis Robert A. Rosenheck and Douglas L. Leslie; 5. Psychosocial functioning in patients with chronic schizophrenia: findings from the NIMH CATIE study Marvin S. Swartz; 6. Neurocognition Richard S. E. Keefe; 7. Vocational outcomes Sandra G. Resnick and Robert A. Rosenheck; 8. Family outcomes Deborah A. Perlick, Richard Kaczynski and Robert A. Rosenheck; 9. Extrapyramidal side effects Stanley N. Caroff, Del D. Miller and Robert A. Rosenheck; 10. Metabolic side effects and risk of cardiovascular disease Jonathan M. Meyer, Donald C. Goff and Joseph P. McEvoy; 11. Substance use in persons with schizophrenia: incidence, baseline correlates, and effects on outcome Fred Reimherr, Marvin S. Swartz and John L. Olsen; 12. Violence in schizophrenia: prevalence, correlates, and treatment effectiveness Jeffrey Swanson and Richard Van Dorn; 13. Genetic investigations in the CATIE sample James J. Crowley and Patrick F. Sullivan; 14. Human subjects considerations T. Scott Stroup and Paul Appelbaum; 15. Population pharmacokinetics of antipsychotics Kristin L. Bigos, Robert R. Bies, Stephen R. Marder and Bruce G. Pollock; 16. Implications for research design and study implementation T. Scott Stroup and Jeffrey A. Lieberman; 17. Conclusion and implications for practice and policy Robert A. Rosenheck, T. Scott Stroup and Jeffrey A. Lieberman.