Calcium: The molecular basis of calcium action in biology and medicine

Inbunden, Engelska, 2000

2 224 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Beskrivning

The final section gives information on new methods and devices for calcium imaging, and illustrates how calcium movement and change can be monitored and ingeniously utilized as a fast, cheap, and accurate drug screening instrument.

Produktinformation

Utgivningsdatum:2000-11-30
Mått:155 x 235 x 46 mm
Vikt:1 314 g
Format:Inbunden
Språk:Engelska
Antal sidor:732
Upplaga:2000
Förlag:Kluwer Academic Publishers
ISBN:9780792364214

Utforska kategorier

Fysiologi inom Medicin
Medicinsk genetik inom Medicin

Innehållsförteckning

From Genes to Drugs.- Ca2+ Release in Muscle Cells.- Calcium Signalling in Neurons Exemplified by Rat Sympathetic Ganglion Cells.- Calcium and Platelets.- Calcium Signalling in Liver Cells.- Intercellular Calcium Signalling in “Non-Excitable” Cells.- The Ca2+-Mobilizing Second Messenger Cyclic ADP-Ribose.- Visinin-Like Proteins (VILIPs) — Emerging Role in Cross-Talk between Cellular Signaling Pathways.- Calcium Binding to Extracellular Matrix Proteins, Functional and Pathological Effects.- The Extracellular Calcium-Sensing Receptor: Molecular Features, Distribution and Its Roles in Physiology and Disease.- Regulation of Inositol 1,4,5-Triphosphate-Induced Ca2+ Release by Ca2+.- Calreticulin and Dynamics of the Endoplasmic Reticulum Lumenal Environment.- Ryanodine-Sensitive Calcium Release Channels.- Calcium Inhibition of Cytoplasmic Streaming.- Penta-EF-Hand (PEF) Proteins and Calsenilin/DREAM: Involvement of the New EF-Hand Calcium-Binding Proteins in Apoptosis and Signal Transduction.- Activation of Programmed Cell Death by Calcium: Protection against Cell Death by the Calcium Binding Protein, Calbindin-D28k.- Calcium and Cellular Ageing.- The Epidermal Growth Factor Receptor and the Calcium Signal.- Annexinopathies.- Autoimmune Disease and Calcium Binding Proteins.- Calcium Antagonists and Calcium Sensitizers.- Calcium-Binding Proteins in Type I Allergy: Elicitors and Vaccines.- Calcium Channelopathies in Nervous System.- Calcium and Diabetes.- Inherited and Acquired Disorders of Extracellular Calcium (Ca02+)-Sensing.- Calcium and Muscle Disease: Pathophysiology of Calpains and Limb-Girdle Muscular Distrophy Type 2a (LGMD2A).- Role of Calcium Channels in Drug Dependence.- S100 Proteins and Fatty Acid Transport Are Altered in Skin Diseases.- Calcium-BindingProteins in Degenerative and Cancer-Related Diseases of the Eye.- Calcium ATPases Genes and Cell Transformation.- Interaction of Dimeric S100B (??) with the Tumor Suppressor Protein p53: A Model for Ca2+-Dependent S100-Target Protein Interactions.- The Interaction of Calmodulin with Novel Target Proteins.- Type II Citrullinemia (Citrin Deficiency): A Mysterious Disease Caused by a Defect of Calcium-Binding Mitochondrial Carrier Protein.- High Calcium Concentrations, Calpain Activation and Cytoskeleton Remodeling in Neuronal Regeneration after Axotomy.- Genetic Factors and the Role of Calcium in Alzheimer’s Disease Pathogenesis.- The Role of Intracellular Calcium Signaling in Motoneuron Function and Disease.- Pharmaceutical Chemistry and Drug Screening.- Calcium in Drug Screening.- Imaging Intracellular Calcium in Living Tissue by Laser-Scanning Confocal Microscopy.- Immature Mouse Oocyte as a Model for Imaging Nuclear Calcium Dynamics.- Single Cell Fluorescence Imaging to Investigate Signaling in Primary Cultured Neurones.- Calcium Complexities: New Fluorescence Techniques for Probing Mitochondria and Other Subcellular Compartments.